Objective To observe the effects of progressive resistance training(PRT)combined with hyperextension traction elastic pressure on pain indexes and rehabilitation outcome in patients with osteoporotic vertebral compression fracture(OVCF)after percutaneous vertebroplasty(PVP).Methods A total of 98 OVCF patients were randomly divided into observation group and control group,with 49 cases in each group.All underwent PVP following preoperative hyperextension traction elastic pressure.After operation,control group was given routine rehabilitation training,while observation group was treated with PRT in addition to routine rehabilitation training.All were intervened for 3 months.The changes of imaging indexes,lumbar pain indexes,lumbar function indexes,bone metabolism indexes and activities of daily living before,at 1 week and 3 months after operation were observed.Results Three months after operation,the anterior vertebral height was higher(P<0.05)and Cobb Angle was lower(P<0.05)in observation group than in control group.Compared with control group,observation group had lower scores on visual analog scale and Oswsetry disability index,obtained higher Japanese Orthopaedic Association score for low back pain,scored higher on activities of daily living scale,and showed lower levels of serum osteocalcin and bone specific alkaline phosphatase(all P<0.05).Conclusion Hyperextension traction elastic pressure before PVP combined with PRT after surgery can better reduce postoperative lumbar pain index,and promote bone growth,further improving lumbar function and activities of daily living in OVCF patients.

Random systematic biopsy is the standard method for diagnosing prostate cancer. As the improvement of multi-parameter magnetic resonance imaging (mpMRI) and its corresponding scoring system, magnetic resonance imaging(MRI)-targeted target biopsy has been an effective alternative to traditional systemic puncture. Prostate imaging reporting and data system(PI-RADS) is the most commonly used MRI-scoring system. The negative rate of prostate cancer in the patient with PI-RADS scores of 1 and 2 was 90.8%(95% CI, 88.1%~93.1%), and the diagnosis rates of clinically meaningful prostate cancer in the patient with PI-RADS scores of 3, 4, and 5 was 20.9%, 58.3% and 80.7%, respectively. That means that MRI targeted prostate biopsy can more effectively detect clinically meaningful prostate cancer on the basis of reducing unnecessary punctures. There are three effective MRI guided target biopsy method for prostate biopsy, including MRI guided target biopsy(MRI-TB), MRI-TRUS fusion target biopsy(FUS-TB) and cognitive fusion target biopsy(COG-TB). Considering the false negative rate and discrepant image quality, MRI-targeted target biopsy still cannot completely replace the traditional systemic puncture. However, it can be seen that the targeted combined system puncture is the future development trend.