To study the anti-inflammatory effects of the combinations of active components of Painong powder, a compound traditional Chinese herbal medicine, and the quantitative analysis of their interactions.

Objective Cariprazine is the first orally active dopamine D3-preferring D3/D2 receptor partial agonist as antipsychotic agents.It receives a lot of concern for its remarkable efficacy and broad market prospect.In this article,overall application status of cariprazine patent,which includes the patent application quantity,applicants and technical topics,as well as possible technical obstacles were statistically analyzed.Methods The patent quantitative analysis method was used,combing with pharmacy expertise,to analyze the patent application situation at home and abroad.Results The patent technology of cariprazine involves product,process,new use,component of combination,formulation and general interest.Conclusions The concern of patent situation for cariprazine was high.Patents about different salt and its crystal,analytical method and impurities should be dug up by domestic generic pharmaceutical enterprises for further generic drug development considering the existing technology barrier.