1.Erectile dysfunction and cancer: current perspective
Renu MADAN ; Chinna Babu DRACHAM ; Divya KHOSLA ; Shikha GOYAL ; Arun Kumar YADAV
Radiation Oncology Journal 2020;38(4):217-225
Erectile dysfunction (ED) is one of the major but underreported concerns in cancer patients and survivors. It can lead to depression, lack of intimacy between the couple, and impaired quality of life. The causes of erectile dysfunction are psychological distress and endocrinal dysfunction caused by cancer itself or side effect of anticancer treatment like surgery, radiotherapy, chemotherapy and hormonal therapy. The degree of ED depends on age, pre-cancer or pre-treatment potency level, comorbidities, type of cancer and its treatment. Treatment options available for ED are various pharmacotherapies, mechanical devices, penile implants, or reconstructive surgeries. A complete evaluation of sexual functioning should be done prior to starting anticancer therapy. Management should be individualized and couple counseling should be an integral part of the anticancer treatment.
2.Erectile dysfunction and cancer: current perspective
Renu MADAN ; Chinna Babu DRACHAM ; Divya KHOSLA ; Shikha GOYAL ; Arun Kumar YADAV
Radiation Oncology Journal 2020;38(4):217-225
Erectile dysfunction (ED) is one of the major but underreported concerns in cancer patients and survivors. It can lead to depression, lack of intimacy between the couple, and impaired quality of life. The causes of erectile dysfunction are psychological distress and endocrinal dysfunction caused by cancer itself or side effect of anticancer treatment like surgery, radiotherapy, chemotherapy and hormonal therapy. The degree of ED depends on age, pre-cancer or pre-treatment potency level, comorbidities, type of cancer and its treatment. Treatment options available for ED are various pharmacotherapies, mechanical devices, penile implants, or reconstructive surgeries. A complete evaluation of sexual functioning should be done prior to starting anticancer therapy. Management should be individualized and couple counseling should be an integral part of the anticancer treatment.
3.Mucoepidermoid carcinoma of the trachea in a 9-year-old male child: case report and review of literature
Deepak Kumar UPPAL ; Renu MADAN ; Nitin J. PETERS ; Amanjit BAL ; Nagarjun BALLARI ; Shikha GOYAL ; Divya KHOSLA
Radiation Oncology Journal 2022;40(3):208-212
Mucoepidermoid carcinoma (MEC) is most common malignancy of minor salivary glands in adults. Pulmonary MEC is extremely uncommon comprising of only 0.1%–0.2% of the primary lung malignancies and <1% of primary bronchial tumors. It is even rarer in children and literature limited to few case reports only. Here we present a case report of a 9-year-old boy diagnosed with primary MEC of trachea along with review of the literature. A 9-year-old male child presented with complaint of dry cough for two years which was later associated with shortness of breath after one year. Bronchoscopic examination revealed a growth arising from right lateral wall of carina occluding 50% of the lumen and detailed histopathological examination revealed it to be a MEC of the trachea. Patient underwent local excision of the tumor with primary anastomosis. In view of positive margins adjuvant radiotherapy of 60 Gy in 30 fractions were given to the tumor bed. Patient tolerated the treatment well and is disease free at 6 months follow-up. Experience with MEC of the trachea in children is limited and optimal treatment protocols have not been defined, with current treatment mainly extrapolated from MEC of the salivary glands.
4.Clinical behaviour and outcome in pediatric glioblastoma: current scenario
Aditya Kumar SINGLA ; Renu MADAN ; Kirti GUPTA ; Shikha GOYAL ; Narendra KUMAR ; Sushant Kumar SAHOO ; Deepak K. UPPAL ; Chirag K. AHUJA
Radiation Oncology Journal 2021;39(1):72-77
Pediatric glioblastoma (pGBM) is a rare entity accounting for only approximately 3% of all childhood brain tumors. Treatment guidelines for pGBM have been extrapolated from those in adult glioblastoma. Rarity of pGBM and underrepresentation of pediatric population in major studies precludes from defining the ideal treatment protocol for these patients. Maximum safe resection is performed in most of the cases followed by postoperative radiotherapy in children over 3 years of age. Benefit of temozolomide is unclear in these patients. Here, we present the clinicopathological details and outcome of six pGBM patients treated at our institute in 2018–2019.
5.Clinical behaviour and outcome in pediatric glioblastoma: current scenario
Aditya Kumar SINGLA ; Renu MADAN ; Kirti GUPTA ; Shikha GOYAL ; Narendra KUMAR ; Sushant Kumar SAHOO ; Deepak K. UPPAL ; Chirag K. AHUJA
Radiation Oncology Journal 2021;39(1):72-77
Pediatric glioblastoma (pGBM) is a rare entity accounting for only approximately 3% of all childhood brain tumors. Treatment guidelines for pGBM have been extrapolated from those in adult glioblastoma. Rarity of pGBM and underrepresentation of pediatric population in major studies precludes from defining the ideal treatment protocol for these patients. Maximum safe resection is performed in most of the cases followed by postoperative radiotherapy in children over 3 years of age. Benefit of temozolomide is unclear in these patients. Here, we present the clinicopathological details and outcome of six pGBM patients treated at our institute in 2018–2019.