1.Application value of CT in the diagnosis and invasive evaluation of gastrointestinal stromal tumors
Chinese Journal of Postgraduates of Medicine 2014;37(15):38-40
Objective To analyze the application value of CT in the diagnosis and invasive evaluation gastrointestinal stromal tumors (GIST).Methods The clinical data of 72 GIST cases examined by spiral CT scan and confirmed by surgery or pathology were analyzed retrospectively,evaluated the invasiveness by the tumor site,pattern,strengthen forms,plain and dual-phase enhanced CT scan value.Results GIST most commonly occurred in the stomach.Forteen cases were misdiagnosed in 72 cases of GIST patients,diagnosis of 5 cases was not made clearly.The differences between arterial,venous phase and scan difference in the same parts of different GIST classification were statistically significant (t =4.2,3.5,13.1,15.8,P < 0.05).The GIST in the same part of the different risk classification scan,arterial,venous CT values;difference between the arterial and scan,venous and scan,the difference was not statistically significant (t =34.8,28.5,39.4,32.2,40.1,P > 0.05).Reconstructed image could show the relationship among the tumor and its surrounding tissue and tumor feeding artery,the existence of which 33 cases of portal collateral,18 cases with the presence of arteriovenous fistula and 17 cases with liver metastasis.Conclusions Invasive different GIST dual-phase enhanced CT scans show that arteriovenous tumors are significantly enhanced;post-processing techniques can help clear the blood vessels and GIST relations with neighboring vessels and tissue imaging requires multi-disciplinary preoperative information analysis to make the right location and diagnosis.
2.Evaluation of therapeutic effect and safety of the umbilical blood stem cell transplantation on patients with end-stage cirrhosis
Shijun ZHOU ; Ying YE ; Jiabin LI
Acta Universitatis Medicinalis Anhui 2016;51(7):1035-1038
Objective To observe the therapeutic effect and safety of the umbilical blood stem cell transplantation on patients with end-stage cirrhosis.Methods We chose 80 patients diagnosed with end-stage cirrhosis.All the re-lated contraindications were excluded .Communicated with all the patients, 50 patients chose the umbilical blood stem cell transplantation and conservative treatment , and 30 patients only chose conservative treatment .The 50 pa-tients were defined as observation group and the left were defined as control group .After transplantation, clinical symptoms and laboratory data were recorded at the 1 month, 6 month, and 12 month.Results ① 12 months after transplantation, clinical symptoms were improved in 38 cases(76%) in the observation group and that in 12 cases (40%) in the control group.② The laboratory data, including ALB, TBiL, ALT, AST, PTA were improved after transplantation in observation group (P <0.05).No significant difference was found in the control group after thera -py.③ After transplantation, the improvement of ALB, A/G, TBiL, PTA in observation group was higher than the control group(P <0.05).Conclusion After transplantation of the umbilical blood stem cell transplantation , the liver function and life quality of patients are significantly improved .This method is better than conservative treat -ment.The method is safe and effective in the treatment of patients with end -stage cirrhosis.
3.Research and Practice on Medical Humanities Curriculums
Xiaoyan ZHOU ; Shijun YAN ; Yuntao WU
Chinese Journal of Medical Education Research 2003;0(04):-
This article gives insights into a series of research on the purpose, significance, system, execution and as-sessment of Medical Humanities Curriculums, based on the problems of the existing medical education. The MedicalHumanities Curriculums are divided into three major groups: the fundamental, the comprehensive and the practical,detailedly reasoned by their contents and functions.[
4.Percutaneous vertebroplasty:treatment of vertebral osteoporosis fractures with intraosseous cyst
Shijun MI ; Jingchun GAO ; Guangjun ZHOU
Orthopedic Journal of China 2006;0(12):-
[Objective]To determine the efficacy and characteristics of percutaneous vertebroplasty in treating patients with vertebral osteoporosis fractures combined with intraosseous cyst.[Method]Thirteen cases of vertebral osteoporosis fractures combined with intraosseous cyst were performed with percutaneous vertebroplasty.Bone cement containing appropriate proportion allograft bone powder were injected to vertebral body according to the sererity of osteoporosis and the size of intraosseous cyst.[Result]According to standard of World Health Organization about pain,complete pain relief was in 10,partial in 2,and slight in 1 patient.One case developed bone cement leakage into the paravertebral soft tissues during operation,but there were no clinical signs and symptoms.The next vertebral body fracture was found at sixteen days after percutaneous vertebroplasty in 1 case,and percutaneous vertebroplasty was repeated to relieve his pain.This patient was followed-up for 1 year,and no refracture was observed.[Conclusion]Vertebral osteoporosis fractures combined with intraosseous cyst is a special disease in elderly population.Percutaneous vertebroplasty is effective and it shouled be the first option for treatment of patients with vertebral osteoporosis fractures combined with intraosseous cyst.The complications could be reduced by local treatment combined with anti-osteoporosis drugs and correct rehabilitation.
5.The effect of triradiate cartilage injury on hip development
Hongqiang WANG ; Shijun JI ; Yongde ZHOU
Chinese Journal of Orthopaedics 1998;0(12):-
Objective To study the effect of premature physeal fusion of t ri radiate cartilage on hip development. Methods Ten rabbits aged 4 to 5 weeks were used by partial excision of triradiate physeal cartilage on the right hip of ea ch rabbit, and the opposite untreated hip served as control. Postoperative analy sis consisted of radiographic and histological studies. Radiographs of both hips were taken at 2 days and 3, 6, 9 and 12 weeks after surgery to evaluate the dev elopment and stability of hips. All rabbits were sacrificed at 12 weeks postoper atively. The gross and microscopic histological changes of the hip joints were s ubsequently assessed. The statistic analysis was performed by paired student’s t test worked out by SPSS software. Results On the operated hips, bone bridge fo rmed 3 weeks after operation at the site of triradiate cartilage. The medial ace tabular walls became thick, and the acetabula were shallow. At 6 and 9 weeks pos toperatively, the thickness of acetabular walls increased gradually, and irregul ar sclerosis appeared on the acetabular roof. The density of femoral head increa sed in 6 of 10 rabbits. At 12 weeks postoperatively, the acetabular cavity was m ore shallow, and the femoral head appeared flat. Subluxation of hip was observed in 5 rabbits. There was significant difference in approximate acetabular index (AAI), acetabular head index (AHI) and the thickness of acetabular wall between the operated and control hips. The mean value of AAI and AHI on the operated hip s at 12 weeks significantly decreased as compared to that at 2 days. Gross inspe ction confirmed that the acetabular cavity on the operated hips was characterist ically shallow with a marked increase thickness of medial wall. The femoral head became flattened, and the cartilage of both acetabulum and femoral head were th inned. Histological study showed thinning and partial loss of the joint cartilag e layer and irregularity of cartilage cells on the operated hip joints. There we re increased amounts of fibrovascular cells deep to the cartilaginous layer. In addition, the femoral head exhibited a zone of necrosis in its superior pole wit h thinning of the epiphyseal plate. On the control hips, structure of acetabulum and femoral head appeared normal congruity. Conclusion Acetabular triradiate ca rtilage injury might result in bony bar formation and premature fusion of physis . Its main pathologic changes are widening of the acetabular medial wall, shallo wness of the acetabular cavity, and subsequent hip dysplasia and dislocation.
6.Long- term evaluation of intracystic corticosteroid injection in the treatment of simple bone cysts
Lijun ZHANG ; Shijun JI ; Yongde ZHOU
Chinese Journal of Orthopaedics 2000;0(02):-
Objective To evaluate the long- term results of intracystic corticosteroid injection for the treatment of simple bone cysts. Methods Seventy- six children with simple bone cysts treated by intracystic injection of corticosteroid from 1985 to 1995 were followed- up for an average of 8.2 years( 5- 13 years) . Forty- one of the cysts were situated at the proximal end of the humerus, 20 at the proximal end of the femur and 15 at other sites. The mean injection times were 4.2(2- 13 times). Results Forty- two(55.3% ) cysts were healed up completely, 16(21.1% ) basically healed up, 9(11.8% ) healed up partially and 9(11.8% ) failures. Satisfactory and effective rate was 76.4% and 88.2% respectively. Conclusion Intracystic corticosteroid injection appears to be the initial choice of treatment for simple bone cysts, because it is an effective, and non- invasive method which can be carried out easily.
7.Clinical Determination and Reason of Poststroke Dementia
Yanhui YI ; Haifeng PENG ; Shijun ZHOU
Journal of Chinese Physician 2001;0(06):-
Objective To analyze the clinical determination and mechanism of poststroke dementia.Methods 186 consecutively hospitalized patients who at admission after stroke,completed clinical valuation of neural-functional defect and intelligence assessments,and head CT scan.Their intelligene performances were assessed again after three months .Results Frequency of poststroke dementia was 32 5% .Poststroke dementia was related to age,level of education,residential area,hypertension ,hyperlipidemia,the location and severity of stroke,history of coronary heart disease and diabetes.But it unrelated to sex,smoking,alcohol drinking and type of stroke.Conclusions Dementia is frequently occurred after stroke,and multiple risk factors contribute to its occurrence
8.A Study of Relationship Between Intelligence Condition of the Epileptic Patient and ?-GABA in CSF
Haifeng PENG ; Shijun ZHOU ; Hangjun TANG
Journal of Chinese Physician 2001;0(10):-
Objective To explore the relationship between the intelligence condition and the content of ?-aminobutyric acid (GABA) in cerebrospinal fluid (CSF) in epileptic patients.Methods We measured the Intelligence Quotient (IQ) of 40 cases of epileptic patients by using the Wechsler Intellectual Scaled, and tested their CSF-GABA contents by using HPLC.At the same time, factors which might have influence on patient’s IQ were analysed.Results In the 40 cases of epileptic patients, there were 14 cases of patients with FIQ≤89, and occupied 35%.The intelligence condition of epileptic patients was positive relation with the contents of CSF-GABA, education background and patterns of seizure,but was negative relation with the patient's age. Among all factors, content of CSF-GABA was very significant relationship with VIQ, PIQ and FIQ (P
9.CT-guided percutaneous injection of bone cement for treating osteolysis pelvic disease in 9 cases
Shijun MI ; Jingchun GAO ; Shijun ZHAO ; Guangjun ZHOU ; Wanxu GAO ; Jingyu SUN
Chinese Journal of Tissue Engineering Research 2010;14(8):1467-1470
BACKGROUND: Osteolysis has always occurred in pelvis. Percutaneous injection of bone cement stabilized bone fracture, relieved pain or even treated tumor. However, leakage of bone cement might cause severe complications. OBJECTIVE: To explore the therapeutic effect of peroutaneous injection of bone cement on treating osteolysis pelvic disease in 9 cases by the CT guidance. METHODS: By the CT guidance, needing degree was determined firstly. Focal size and scanning layers were used to calculate focal volume and estimate injected dose of bone cement. Three-dimensional targeting device was used to introduce the puncturation. The bone cement which was 0.2-0.5 mL less than the calculated volume was injected into osteolysis site. The accuracy, injected dose, clinical efficacy, and complications were investigated. RESULTS AND CONCLUSION: The following-up ranged from 5 months to 4 years, with mean duration of 1.5 years. At 1-48 hours after operation, symptoms were recovered, including complete recovery (n=6), partial recovery (n=2), and light recovery (n=1). Leakage of bone cement was not detected out around focal region. This suggested that percutaneous injection of bone cement into the erosion site is an effective method to treat pelvic osteolysis disease, characterizing by security, effective, and less invasive.