1.Epidemiological characteristics of canine Echinococcus infection in Qinghai⁃ Tibet Plateau of China
Hui LIU ; Ning XIAO ; Shijie YANG ; Dong WANG ; Jia PENG
Chinese Journal of Schistosomiasis Control 2017;29(2):129-138
The Qinghai⁃Tibet Plateau is known as one of the highest endemic areas of echinococcosis However,the dog infection rates of Echinococcus granulosus in the plateau regions were similar to other non⁃Tibetan areas with the high endemic,and most of the rates were below 40%. The infected dogs with E. multilocularis were ubiquitous in Ganzi Prefecture of Sichuan Province and Qinghai Province where many survey data were done and available,which was much different from those in non⁃Ti⁃betan areas where the geographical distribution of dogs infected with E. multilocularis was sporadic. The total infection rates of Echinococcus in dogs kept stable from 1983 to 2009 in Ganzi Prefecture of Sichuan Province and did not show much variation from 2000 to 2014 in Qinghai Province as well. Since 2006,the national comprehensive prevention and control strategy and mea⁃
sures against echinococcosis have been launched in China,and significant progress has been made. In the endemic Tibetan area of Sichuan,the general Echinococcus infection rates in dogs were 28.10%,15.87%,19.22%,3.28% and 1.11% from 2009 to 2013,respectively,and the Echinococcus coproantigen⁃positive rate in Gannan Prefecture of Gansu Province and parts of Qing⁃
hai Province also decreased. This paper reviews the literature on the characteristics of dog infections in the Qinghai⁃Tibetan Plateau,so as to provide useful information to support echinococcosis control and prevention there.
2.Flexible spectral imaging color enhancement for determining the demarcation of early gastric cancer and precancerous lesions
Shijie YU ; Yanxia LI ; Lei SHEN ; Weiguo DONG ; Hesheng LUO
Chinese Journal of Digestive Endoscopy 2013;(1):36-38
Objective To evaluate the flexible spectral imaging color enhancement (FICE) system for determine the margin of early gastric cancer and precancerous lesions.Methods From February 2008 to October 2011,a total of 51 patients with early gastric cancer or high-grade intraepithelial neoplasm who received ESD were enrolled and randomly divided into experimental group to determine lesion margin by FICE (n =26) and control group to identify lesion margin by indigo carmine (n =25).Histological complete resection rate (the lateral and vertical margins were free of cancer),operation time,complications,post-ESD ulcer-healing rates and local recurrence were assessed.Results The histological complete resection rate,acute minor bleeding rate and post-ESD abdominal pain rate in experimental group were 2.3% (24/26),88.5% (23/26),15.4% (4/26) and 73.1% (19/26),which were not significantly different from those of control group,i.e.,92.0% (23/25),84.0% (21/25),12.0% (3/25)and 72.0% (18/25) (P>0.05).The mean operation time of in experimental group was shorter than that of control group (P < 0.05).No massive bleeding,delayed bleeding or perforation occurred in either group.Follow-up showed no local residue or recurrence.Conclusion FICE is safe and effective to determine the tumor demarcation of early gastric cancer and high-grade intraepithelial neoplasm,and needs less operation time.
3.Diagnostic value of CT in subarachnoid hemorrhage induced by aneurysm rupture
Tongjun SONG ; Jiangong WEI ; Shiqiang WANG ; Daobin LIU ; Shijie DONG
Chinese Journal of Primary Medicine and Pharmacy 2013;20(4):524-525
Objective To explore the diagnosis value of CT in subarachnoid hemorrhage(SAH) induced by aneurysm rupture.Methods The clinical and CT data of 119 patients with SAH induced by aneurysm rupture were analyzed respectively.Results The CT characteristic of SAH induced by aneurysm rupture was full of hyperderse in sulcus and schizenceplay,or accompaning intracerebral hematoma in the straight gyrus of frontal lobe and the hippocampal gyrus of parietal lobe.Conclusion The CT has important value for diagnosing SAH induced by aneurysm rupture in the location and the nature.But it is indispensable that the CTA or DSA must be done for ascertaining the artery of responsibility of rupturing aneurysm.
4.A STUDY ON LYMPHATIC SYSTEM OF THE RENAL PEDICLE IN CHINESE
Yunhou DONG ; Shijie XU ; Yulan LI ; Chongliang HE ;
Acta Anatomica Sinica 1957;0(04):-
159 kidneys from infant and neonatal cadavers were dissected under stereoscope.The study showed that there were a lot of lymphatics(11.11?2.48) originating fromthe lymphatic network of renal sinus.The lymphatics of renal pedicle variedslightly in diameter (0.25-0.40 mm).The mean value of the diameter oflymphatics in the renal pedicle was 4mm.The mean value of the ratio ofdiameter of lymphatics to that of renal vein on the same side is 90.47%.Therewere positive correlation between them.The renal lymph nodes were scattered singlyin number in each kidney.
5.A Clinical Study On Vindesine in the Interventional Treatment of Hepatic and Pulmonary Carcinomas
Shijie SHI ; Ying ZHAN ; Dong JIANG ; Gun LING ;
Journal of Interventional Radiology 1992;0(01):-
Purpose:To evaluate the efficacy and toxicity of vindercine(VDS)in the interven- tional treatment of hepatic and pulmonary carcinomas.Materials and Methods:30 cases of mid-ad- vanced hepatic and pulmonary carcinomas,among them,13 eases of primary hepatic carcinomas,7 cases of matastic hepatic carinomas and 10 cases of primary pulmonary carcinomas,were treated by selective arterial infusion chemotherapy.The combination chemotherapeutic regimens conpored of VDS together with 5-Fu,MMC,carboplatin or Vp16.Results:The response rate for all cases was 60%,for primary hepatic carcinomas 61.5%,for metastic hepatic carcinoma 42.9% and for primary pulmonary carcinoma 70%.Myelosuppession was the main toxicity and 70% patients had the gastrointertional reac- tions as nusea,vomiting etc.Conclusion:VSD is a more effective drug for pulmonary carcinoma,but for hepatic carcinoma,the efficacy of VDS was unmarkable from other drugs.
6.Effects of Carotid Sympathectomy on Intercurrent Damage of Refractory Cerebral Palsy:204 Cases Report
Shijie WANG ; Yetao CHEN ; Haisheng LIU ; Dong WANG ; Yunpeng WANG ; Huanzong ZUO
Chinese Journal of Rehabilitation Theory and Practice 2008;14(9):858-859
Objective To study the effects of carotid sympathectomy on symptom or intercurrent damage of refractory cerebral palsy.Methods 204 cases with cerebral palsy of mixed type and with intercurrent damage were treated with bilateral carotid sympathectomy.Results 187 cases(91.7%) were followed up successfully,which showed 74.4% of torsion or tension spasm,42% of athetosis,63.6% of cognition language disturbance,81.6% of sialorrhoea,27.6% of strabismus and 88% of deglutition handicap improved.The scores of activity of daily living improved 43.8%.The total incidents effective rate was 82.7%.Conclusion Carotid sympathectomy is an effective and safe microsurgery method for the symptom or intercurrent damage of the refractory cerebral palsy.
7.Evaluation of acute kidney injury network criteria in post-cardiosurgery elderly patients with acute kidney injury
Xiaolei YAN ; Xiaotong HOU ; Yong YANG ; Ping DONG ; Ming JIA ; Jiuhe WAN ; Shijie JIA
Chinese Journal of Geriatrics 2010;29(1):24-26
Objective To evaluate the value of acute kidney injury network (AKIN) criteria for predicting hospital mortality in post-cardiosurgery elderly patients. Methods From October 2006 to January 2007, the elderly patients who underwent coronary artery bypass grafting or valve replacement operation were enrolled in this study. The medical data included gender, age, operation type, perioperative hemodynamic parameters, urine output, biochemical parameters and outcome. Renal function was assessed according to the AKIN criteria, and severity of illness was determined after surgery by calculating Acute Physiology and Chronic Health Evaluation Ⅱ (APACHE Ⅱ ) score. Results A total of 225 patients underwent cardiac surgery during this period, 169 patients were male (75. 1%), while 56 were female (24. 9%), mean age was (66. 7±5. 0) years old. The overall hospital mortality rate was 5.8% (13/225). According to AKIN criteria, there were 125 patients with acute kidney injury (55.6%), and the hospital mortality of stage 1, 2 and 3 patients were 2. l%(2/96), 9. 1% (1/11) and 50. 0% (9/18) respectively. A significant increase was observed in mortality based on AKIN criteria (P<0. 01). By applying the area under the receiver operating characteristic curve, the AKIN criteria had a good discriminative power. Conclusions Both the incidence and mortality rate of acute kidney injury in the post-cardiosurgery elderly patients are high, the AKIN criteria is a simple and valuable method with a good prognostic capability for evaluating acute kidney injury.
8.Aberrant promoter methylation of SFRP1 and SFRP2 gene in gastric cardia adenocarcinoma
Zhiming DONG ; Fuli WANG ; Guoliang JIN ; Wei GUO ; Yanli GUO ; Shijie WANG
Cancer Research and Clinic 2009;21(12):799-802
Objective To investigate the promoter methylation status of SFRP1 and SFRP2 gene in gastric cardia adenocarcinoma (GCA). Methods Methylation specific PCR (MSP) method was used to examine the methylation status of the 5' CpG island of SFRP1 and SFRP2 gene in tumors and corresponding normal tissues. Results Methylation frequencies of SFRP1 and SFRP2 gene in tumor specimens were 87.2 % (82/94) and 83 %(78/94), which was significantly higher than that in corresponding normal tissues (14.9 % and 55.3 %, respectively) (P <0.001). Methylation frequencies of SFRP1 in lymph node metastasis group (96.4 %) was significantly higher than that in no lymph node metastasis group (73.7 %). Methylation frequencies of SFRP1 and SFRP2 gene in poor differentiation group were all higher than that in moderate and poor-moderate differentiation groups, but both of them did not show significant difference(P >0.05). 63 cases of GCA showed both of SFRP1 and SFRP2 gene simultaneous methylation, which including 36 cases of lymph node metastasis group, 27 cases of no lymph node metastasis group. Simultaneous methylation frequencies of SFRP1 and SFRP2 gene in lymph node metastasis group was higher than that in no lymph node metastasis group, poor differentiation group was higher than that in moderate and poor-moderate differentiation groups, but both of them did not show significant difference (P >0.05). Conclusion Promoter methylation of SFRP1 and SFRP2 might be related with oncogenesis of GCA and hypermethylation of SFRP1 gene might be related with the malignant behavior of GCA.
9.An improved software design of ultrasound bone densitometer.
Zhengtao YU ; Lian YANG ; Shijie XU ; Jiangjun DENG ; Qingqing DONG ; Aijun HE
Journal of Biomedical Engineering 2014;31(5):1061-1064
In order to meet the requirements of ultrasound bone density measurement, we proposed a software solution to improve the accuracy and speed of measurement of bone mineral density of the ultrasound bone densitometer. We used a high-speed USB interface chip FT232H, along with a high-speed AD converter chip to calculate speed of sound (SOS), broadband ultrasound attenuation (BUA ) and other bone density parameters in the PC software. This solution improved the accuracy of the measurement data, reduced the measurement time and increased the quality of the displayed image. It is well concluded that the new software can greatly improve the accuracy and transmission speed of bone density measurement data through a high-speed USB interface and a software data processing technology.
Absorptiometry, Photon
;
Bone Density
;
Software
;
Sound
;
Ultrasonics
10.Research of left-atrial fibrosis of atrial fibrillation patient and its effect to post-operative rhythm of radiofrequency ablation treatment
Fei LI ; Xu MENG ; Jie HAN ; Ping DONG ; Yong YANG ; Shijie JIA
Chinese Journal of Thoracic and Cardiovascular Surgery 2013;29(9):537-540
Objective To research the fibrosis characteristics of Atrial Fibrillation(AF) patients under microscope and its effect to post-operative sinus conversion of Radiofrequency ablation treatment.Methods Based on Lefi Atrial Dimension (LAD).Left atrial appendage tissue samples of 60 AF patients who received bipolar radiofrequency ablation treatment during open heart surgery between July and December 2011,were divided into 4 groups:group a (LAD≤50 mm),group b (50 mm < LAD≤60 mm),group c (60 mm< LAD ≤70 mm),group d (LAD > 70 mm),15 patients in each group.The levels of atrial muscle fibrosis and cell size differences are compared for colored slides of samples.Research are done for the difference of sinus rhythm restoration rate among the 4 groups based on ECG records at immediate,leaving hospital,and 3,6,12 months postoperative are collected for all groups.Results Differences of CVF and atrial muscle cell size measured under microscope are statistically meaningful(P < 0.001).Sinus rhythm restoration rate differences at 6 month(P =0.039) and 12 month (P =0.037) post-operative are statistically meaningful.Further,immediate,leaving hospital,and 3,6,12 months postoperative sinus rhythm restoration rates are 93.3%,93.3%,93.3%,100%,100% for group a,80.0%,73.3%,80.0%,80.0%,80.0% for group b,66.7%,66.7%,66.7%,73.3%,66.7% for goup c,and 53.3%,53.3%,53.3%,60.0%,60.0% for group d respectively.Conclusion For rheumatic heart valve diseases patients who at 6 and 12 month post-operative,the greater the LAD,the higher the atrial fibrosis level,the greater the cell size,the lower the sinus rhythm restoration rate is.