1.A Case of Antiresorptive Agent-Related Osteonecrosis of the Jaw Successfully Treated with Hochuekkito
Yuzo FUKUSHIMA ; Hisao ITO ; Shugo TAGASHIRA ; Shigeto YANAGIHARA ; Yosuke NAKAMURA ; Ryosuke FUJITA
Kampo Medicine 2021;72(3):254-259
We herein report a case of 91-year-old woman with antiresorptive agent-related osteonecrosis of the jaw (ARONJ) developed during treatment for osteoporosis with intravenous ibandronate. Although she was treated with several antibiotics and had an incision for the drainage of a pus discharge at a dental clinic for two months after the onset of ARONJ, the discharge persisted. We then added hochuekkito to her treatment, which resulted in a gradual decreased in pus discharge and decrease in wound size and the wound resolved after approximately one month. ARONJ is considered a refractory disease, however, it was successfully treated with hochuekkito in this patient. ARONJ is also a rare condition and to our knowledge, this is considered to be the first case of ARONJ, which has been successfully treated with Kampo medicine.
2.A Case of Crowned Dens Syndrome Successfully Treated with Kampo Medicine
Yuzo FUKUSHIMA ; Hisao ITO ; Shugo TAGASHIRA ; Shigeto YANAGIHARA ; Yousuke NAKAMURA ; Ryousuke FUJITA
Kampo Medicine 2017;68(4):372-376
Crowned dens syndrome is a type of pseudogout that occurs in the elderly. It is associated with calcification around the dens of the atlas and can cause recurrent pain. We report successful treatment for crowned dens syndrome by using Kampo medicine. An 85-year-old woman was seen in our clinic after 3 days of neck pain and active exercise pain without trigger. Physical examination revealed tenderness in the bilateral upper cervical spine. Computed tomography (CT) revealed calcifications around the dens of the atlas and blood test data showed inflammatory reaction. Thus, she was diagnosed with crowned dens syndrome. In view of her medical history of gastric ulcer treatment, we prescribed Kampo medicine eppikajutsuto and daiobotampito, instead of nonsteroidal antiinflammatory drugs. The cervical pain and tenderness in her bilateral upper cervical spine disappeared, and her laboratory data also improved 6 days after treatment without side effects. Thus, her medications were discontinued.
3.Successful Treatment with Choreito for Recurrent Urinary Tract Infection Treated with Modern Medicine
Ryousuke FUJITA ; Yuzo FUKUSHIMA ; Hisao ITO ; Shugo TAGASHIRA ; Shigeto YANAGIHARA ; Yousuke NAKAMURA ; Minoru OOTAKE
Kampo Medicine 2018;69(4):346-349
Urinary tract infection (UTI) is a common disease, and administration of antibiotics should be the first choice for UTI. However, it often recurs, and recurrent UTI is generally treated with antibiotics. Many reports describe the use of choreito for the treatment of lower urinary tract symptoms and ureteral stones, but only a few reports are dedicated to the treatment of recurrent UTI with choreito. An 84-year-old woman had a UTI that recurred 4 times, and every time she was hospitalized. Although we treated her condition with an antibiotic and α 1-blocker for neurogenic bladder, and provided her home-care advice, her UTI recurred 4 times. Thus, we gave her choreito, which successfully treated her recurrent UTI. Before the treatment, she was hospitalized 4 times within 2 months. However, in the recent 7 months after the treatment with choreito, she did not need to be hospitalized. She is currently visiting a hospital once every 2 months. The present case indicates that choreito is beneficial in terms of health economics.
4.Successfully Treated Acute Lumbago with Daiobotampito and Shimotsuto
Yuzo FUKUSHIMA ; Hisao ITO ; Shugo TAGASHIRA ; Shigeto YANAGIHARA ; Yousuke NAKAMURA ; Ryousuke FUJITA ; Kazuhiko YAMASHITA
Kampo Medicine 2018;69(1):35-41
We report three patients with acute lumbago who did not respond to nonsteroidal anti-inflammatory drugs (NSAIDs), but were treated successfully with daiobotampito and shimotsuto. Case 1 (86-year-old man) and Case 2 (56-year-old woman) were diagnosed with acute lumbago. Case 3 (69-year-old man) was diagnosed with acute lumbago and mild left sciatica. All three patients were initially administered orally NSAIDs, but this treatment was ineffective. Therefore, daiobotampito and shimotsuto were administered after choeikatsurakuto according to “Manbyokaishun.” Following this treatment, the patients' acute lumbago and sciatica resolved within 1-2 weeks. In conclusion, daiobotampito in combination with shimotsuto seems to be a useful Kampo medicine for treatment of lumbago.