Objective：The Mini-Balance Evaluation Systems Test (Mini-BESTest) and Berg Balance Scale (BBS) are widely used to test balance function in adults. However, the information on the minimal clinically important difference (MCID) for the measure has not been consolidated. This review summarizes all available information on the MCID for the Mini-BESTest and BBS.Methods：We searched three electronic databases (PubMed, Cumulative Index to Nursing & Allied Health Literature, and Web of Knowledge) for relevant literature and additionally conducted a hand search.We included all articles that reported an MCID for the Mini-BESTest and BBS.We excluded articles if the MCID was determined by a procedure other than receiver operating characteristic (ROC) curve analysis. Articles were abstracted for information on participants, interventions, balance assessment documentation, and the determination of MCID.Results：A search yielded 21 articles on the Mini-BESTest and 87 articles on the BBS, four articles on the Mini-BESTest and six articles on the BBS were selected based on adherence to the inclusion and exclusion criteria. The MCIDs with an area under the ROC curve of 0.7 or greater ranged from 1.5-4.5 points for the Mini-BESTest and 3.5-6 points for the BBS.Conclusion：A change of 1.5-4.5 points for the Mini-BESTest and 3.5-6 points for the BBS may be clinically important across multiple patient groups.

Objective：The Mini-Balance Evaluation Systems Test (Mini-BESTest) and Berg Balance Scale (BBS) are widely used to test balance function in adults. However, the information on the minimal clinically important difference (MCID) for the measure has not been consolidated. This review summarizes all available information on the MCID for the Mini-BESTest and BBS.Methods：We searched three electronic databases (PubMed, Cumulative Index to Nursing & Allied Health Literature, and Web of Knowledge) for relevant literature and additionally conducted a hand search.We included all articles that reported an MCID for the Mini-BESTest and BBS.We excluded articles if the MCID was determined by a procedure other than receiver operating characteristic (ROC) curve analysis. Articles were abstracted for information on participants, interventions, balance assessment documentation, and the determination of MCID.Results：A search yielded 21 articles on the Mini-BESTest and 87 articles on the BBS, four articles on the Mini-BESTest and six articles on the BBS were selected based on adherence to the inclusion and exclusion criteria. The MCIDs with an area under the ROC curve of 0.7 or greater ranged from 1.5-4.5 points for the Mini-BESTest and 3.5-6 points for the BBS.Conclusion：A change of 1.5-4.5 points for the Mini-BESTest and 3.5-6 points for the BBS may be clinically important across multiple patient groups.

The purpose of this study was to examine the relationship of the Rohrer index and physical activity on motor function. The subjects were 143 elementary school children in the 5th and 6th grades. Motor function was measured based on musculoskeletal examination. The Rohrer index was calculated from height and weight, and ≥140 was defined as a tendency to be overweight. Physical activity was investigated using a self-reported questionnaire, the WHO Health Behaviour in School-aged Children in Japanese version (HBSC-J). A total of 130 students and their parents agreed to participate in this study, and the data of 127 students were analyzed. The main results were as follows: 26 students had a Rohrer index ≥140, and 60 students (47.2%) had abnormalities in one or more items of motor function. In particular, there were many who reported “Impossible to fully squat” and “Limitation of standing forward flexion”. When compared by sex, “Impossible to fully squat”, “Limitation of standing forward flexion”, and “Pain in shoulder” were particularly frequent in boys. The Rohrer index was particularly high in those who reported that it was “Impossible to fully squat”, but it was not associated with HBSC-J. “Impossible to fully squat” was particularly low in HBSC-J (days of Moderate to vigorous Physical Activity and frequency of Vigorous Physical Activity). The results suggested that children of impossible to fully squat is a lot of low activity and obesity. In conclusion, children who are unable to squat should be followed up to promote physical activity and improve obesity.

Online databases are crucial infrastructures to facilitate the wide effective and efficient use of mouse mutant resources in life sciences. The number and types of mouse resources have been rapidly growing due to the development of genetic modification technology with associated information of genomic sequence and phenotypes. Therefore, data integration technologies to improve the findability, accessibility, interoperability, and reusability of mouse strain data becomes essential for mouse strain repositories. In 2020, the RIKEN BioResource Research Center released an integrated database of bioresources including, experimental mouse strains, Arabidopsis thaliana as a laboratory plant, cell lines, microorganisms, and genetic materials using Resource Description Framework-related technologies. The integrated database shows multiple advanced features for the dissemination of bioresource information. The current version of our online catalog of mouse strains which functions as a part of the integrated database of bioresources is available from search bars on the page of the Center (https://brc.riken.jp) and the Experimental Animal Division (https://mus.brc.riken.jp/) websites. The BioResource Research Center also released a genomic variation database of mouse strains established in Japan and Western Europe, MoG+ (https://molossinus.brc.riken.jp/mogplus/), and a database for phenotype-phenotype associations across the mouse phenome using data from the International Mouse Phenotyping Platform. In this review, we describe features of current version of databases related to mouse strain resources in RIKEN BioResource Research Center and discuss future views.

Online databases are crucial infrastructures to facilitate the wide effective and efficient use of mouse mutant resources in life sciences. The number and types of mouse resources have been rapidly growing due to the development of genetic modification technology with associated information of genomic sequence and phenotypes. Therefore, data integration technologies to improve the findability, accessibility, interoperability, and reusability of mouse strain data becomes essential for mouse strain repositories. In 2020, the RIKEN BioResource Research Center released an integrated database of bioresources including, experimental mouse strains, Arabidopsis thaliana as a laboratory plant, cell lines, microorganisms, and genetic materials using Resource Description Framework-related technologies. The integrated database shows multiple advanced features for the dissemination of bioresource information. The current version of our online catalog of mouse strains which functions as a part of the integrated database of bioresources is available from search bars on the page of the Center (https://brc.riken.jp) and the Experimental Animal Division (https://mus.brc.riken.jp/) websites. The BioResource Research Center also released a genomic variation database of mouse strains established in Japan and Western Europe, MoG+ (https://molossinus.brc.riken.jp/mogplus/), and a database for phenotype-phenotype associations across the mouse phenome using data from the International Mouse Phenotyping Platform. In this review, we describe features of current version of databases related to mouse strain resources in RIKEN BioResource Research Center and discuss future views.