Five cases are reported where Daiobushi-to was used for prevention of ileus. The abdominal symptoms that had occurred daily disappeared, and ileus did not recur.
The first case was a 78-year-old female. She had had a uterine myomectomy 23 years previously, and had suffered from ileus repeatedly since then. In November of 1987, she was admitted to the emergency room of the author's hospital for abdominal pain and vomiting. Slight relief of the abdominal pain and vomiting was obtained upon administration of Daikenchu-to via enema, but the Kampo formula was changed to Daiobushi-to due to a lack of bowel movements. Progress has been normal for seven years after this.
The second case was a 34-year-old male. In 1986 he received emergency surgery for a punctured duodenal ulcer. After surgery, he experience attacks of abdominal pain that would appear and disappear. In July of 1989, he was admitted to the hospital complaining of abdominal pain and vomiting. He was diagnosed as having ileus and given a Daikenchu-to enema. Shakuyakukanzo-to-go-Daiobushi-to was also administered, and, five years later, he continues to progress well.
Case 3 was an 87-year-old male who came to the hospital complaining of repetitative ileus. In 1975 he underwent partial gastrectomy for stomach cancer. After surgery he would have to be hospitalized once or twice a year for ileus. In 1984, following unsuccessful preventative treatment, he had surgery for ileus. However, despite the surgery he continued to suffer from symptoms of ileus, finally coming to the authors' clinic in March of 1990. First, Daikenchu-to-go-shokenchu-to was administered for one year, during which ileus did not occur, but in October of 1991 he had a reccurrence requiring hospitalization in the author's department. After a Daikenchu-to enema, Daiobushi-to was administered. He has been free of recurrence for the three years since he was released from the hospital, and has continued to do well up until the present.
Case 4 was a 67-year-old female, who came to the author's department to receive treatment for recurring ileus. She had had a total hysterectomy in 1970 for uterine cancer, and had also recienved radiation therapy. Five years after surgery, she began to suffer form repetitative ileus. Now, two and a half years after commencement of Daiobushi-to administration, her progress is good.
Case 5 was a 70-year-old female who had undergone a partial gastrectomy for stomach cancer in 1992. She began to suffer from constipation after surgery, and developed ileus two months after surgery, requiring emergency hospitalization. She was given Daiobushi-to and has been progressing well for the two years since then.

  On July 7, 2010, a 74-year-old man came to our hospital, complaining that he had a nagging pain in his chest that started the preceding day. After performing electrocardiography, blood tests and electrocardiography, we diagnosed the case as acute myocardial infarction. At first, it was thought that blood flow could be restored in due course of time, antiplatelet and anticoagulant agents were used. Intracardiac catheterization was not included in our initial treatment plan. Three days after the initiation of the treatment, the patient had pain in his left inguinocrural region. Computed tomography and magnetic resonance imaging reveled hematoma in his left iliopsoas muscle. We stopped administering antiplatelet and anticoagulant agents to him. But anemia progressed from Hb14.1g/dL to 9.8 g/dL, so blood transfusions had to be given. After that, the patient underwent a rest cure. With the passage of time, the pain and swelling of the left iliopsoas muscle went down. Regarding the cardiac condition, however, the pain in the chest did not abate even when he was taking a rest. The antiplatelet therapy was resumed, with one type of agent given at first and then with another type added. Examinations using a coronary CT and a cadiac catheter found 90% stenosis at the proximal left anterior descending coronary artery. So, a bare metal stent was placed in the near-closed artery. Ever since, there has been no recrudescence of chest pain and no recurrence of iliopsoas muscle hematoma. The extravascated blood mass seemed to be dissolved spontaneously.

Introduction: Our palliative care staff began the support activity in opioid introduction for outpatients with cancer at Komaki City Hospital in March 2018, because it was difficult to make them understand about proper use of opioid analgesics and misinterpretation about abuse at the time of opioid introduction in outpatient settings. This study aimed to evaluate the effects of the activity (patient education on pain control, telephone follow up, and assessment of the symptom). Method: Outpatients with cancer receiving strong opioids for pain relief from January 2017 to March 2019 were eligible. We retrospectively investigated the difference of the variables between baseline and after the activity as follows; the ratios of prescribing immediate-release opioids, antiemetics, and laxatives when opioids were prescribed and side effects due to opioid analgesics appeared. Results: The study included 122 patients. The prescribing ratios of immediate-release opioids antiemetics and laxatives all increased from 90.7 to 98.5%, from 63.0 to 70.6%, and from 61.1 to 70.6%, respectively. The side effect incidence due to opioids with STAS-J 2 or more decreased from 12 (22.2%) to 9 (13.2%). Discussion: The activity could contribute to the provision of drug treatments and counselling needed for opioid therapy.