1.Comparison of different urinary diversion regimens after minimally invasive resection for bladder cancer patients
Shibao FU ; Xixi FANG ; Shuming HE ; Jinzhu XIAO ; Shanbin ZHANG ; Xianping CHE
China Journal of Endoscopy 2017;23(6):66-70
Objective To investigate the clinical effects of different urinary diversion regimens after minimally invasive resection of bladder cancer. Methods 127 patients with muscular infiltrating bladder cancer from January 2010 to June 2015 were enrolled in this study. According to the patients' condition, they were divided into orthotopic ileal cystectomy group (58 cases), Bricker bladder surgery group (33 cases), ureteral skin ostomy group (36 cases), then compare the clinical data, postoperative complications and quality of life of the three groups. Results There was no significant difference in the ratio of sex, the distribution of age and tumor staging among the three groups. The operation time and postoperative hospital stay in orthotopic ileal cystectomy group were longer than those in the other two groups. The operation time and postoperative hospital stay of the Bricker bladder surgery group were longer than that in ureteral skin ostomy group, the difference was statistically significant; the bleeding in orthotopic ileal cystectomy group was more than the other two groups, and in Bricker bladder surgery group was more than ureteral skin ostomy group, the difference was statistically significant. There was no significant difference in the recovery time of intestinal function among the three groups. The recovery time of intestinal function in ureteral skin ostomy group was shorter than that in the other two groups, the difference was statistically significant. There was no significant difference in the incidence of short-term complications of the three groups of patients. The incidence of long-term complications of orthotopic ileal cystectomy group was significantly higher than the other two groups, the difference was statistically significant. The social function scores, and overall health score of orthotopic ileal cystectomy group were higher than the other two groups, the difference was statistically significance. Conclusion Without external device, closer to the characteristics of physiological urination, orthotopic ileal cystectomy holds higher postoperative quality of life, and higher incidence of long-term complications. With advantages of quick recovery and less complications, ureteral skin ostomy is best for patients who can not stand for long time surgery. It should choose the appropriate surgical approach for patients according to individuals' conditions.
2.Mucor infection in renal grafts from the same donor after renal transplantation
Shanbin ZHANG ; Jinzhu XIAO ; Guoqing ZHANG ; Xianping CHE ; Ning CHEN ; Jun GU ; Shibao FU ; Desheng LI
Organ Transplantation 2015;(5):340-344
Objective To summarize the diagnosis and treatment experience of mucor infection in renal grafts.Methods Clinical data of two patients with mucor infection in renal grafts from the same kidney donor that finally caused renal graft and renal artery rupture were retrospectively studied,and the relevant domestic and foreign literatures were reviewed. Results and conclusions Mucor infection after renal transplantation has no specific manifestation,thus it lacks of means of early diagnosis and is easy to cause misdiagnosis and missed diagnosis.Mucor infection is easy to cause vascular rupture and the prognosis is poor.Early diagnosis, thorough debridement, timely selection of effective antifungal agent, withdrawal of immunosuppressant and correction of coagulation disorders under the monitor of thrombelastogram may improve the survival rate of such patients.
3.Evaluation of combining transvaginal conventional ultrasonography and shear wave elastography on the diagnosis of endometrial cancer
Hui MA ; Zongli YANG ; Fengming ZHANG ; Li YANG ; Qiuying FU ; Peng YANG ; Shibao FANG
Chinese Journal of Ultrasonography 2019;28(4):330-335
Objective To evaluate the combination of transvaginal conventional ultrasonography and shear wave elastography ( SWE) on the diagnosis of endometrial cancer ,and establish a predictive Logistic regression model . Methods Clinical information collection ,transvaginal conventional ultrasonography ,and SWE check were performed in 112 patients w ho were post‐menopausal vaginal bleeding with ≥5 mm thick endometrium . T he Emax and Emean of Young′s modulus for the endometrium were obtained . Pathology was used as the gold standard ,ROC curve was plotted ,which could be used to evaluate the Young′s modulus on the diagnostic effectiveness on endometrial cancer . Single factor analysis and bring logistic regression methods were applied to assess the values of the clinical variables ,transuaginal conventional ultrasonography variables ,and Young′s modulus in the identification of endometrial cancer . Results In 112 cases of endometrial lesions diagnosed by pathology ,there were 84 cases of benign lesions ( benign group) and 28 cases of cancer( malignant group) . Both Emax and Emean in malignant group were larger than benign group [ (53 .00 ± 16 .07) kPa vs ( 31 .99 ± 13 .89) kPa ,( 27 .25 ± 9 .28) kPa vs ( 19 .94 ± 10 .37) kPa ,all P <0 .001] . In the logistical regression analysis ,body mass index ,endometrial thickness ,blood flow grading and Young′s modulus were identified as independent risk factors for endometrial cancer . T he accuracy ,sensitivity and specificity of the logistic regression model in the prediction of endometrial cancer were 89 .29% ,82 .14% , and 91 .67% , respectively . T he area under the ROC curve was 0 .928 . Conclusions T ransvaginal conventional ultrasonography combined SWE technique has an important value in the diagnosis of endometrial cancer .