1.Application of linear and nonlinear characteristics of heart rate variability in assessment of autonomic nervous system activity.
Journal of Biomedical Engineering 2014;31(2):302-307
Calculation of linear parameters, such as time-domain and frequency-domain analysis of heart rate variability (HRV), is a conventional method for assessment of autonomic nervous system activity. Nonlinear phenomena are certainly involved in the genesis of HRV. In a seemingly random signal the Poincaré plot can easily demonstrate whether there is an underlying determinism in the signal. Linear and nonlinear analysis methods were applied in the computer words inputting experiments in this study for physiological measurement. This study therefore demonstrated that Poincaré plot was a simple but powerful graphical tool to describe the dynamics of a system.
Autonomic Nervous System
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physiology
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Heart Rate
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Humans
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Linear Models
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Nonlinear Dynamics
2.Effects of different bladder infusion rates on bladder responses in healthy and complete spinal cord injury rats
Chinese Journal of Physical Medicine and Rehabilitation 2014;36(5):321-324
Objective To investigate the bladder responses to different rates of bladder infusion in healthy and spinal cord injured rats.Methods Fourteen adult female Sprague-Dawley rats were used and divided into two groups:healthy group (n =7) and spinal transection injury group (n =7).The intravesical pressures induced by continuous infusion of saline with different rates under general anesthesia were recorded and compared between the two groups.Results In healthy group the responses of bladder contraction were dependent upon the rate of bladder infusion,and contraction time became shorter while increasing the infusion rate (P < 0.05),i.e.contraction time was (401.0±132.4),(215.7 ±95.9),(108.3 ±59.1) and (52.5 ±32.8)s,respectively,when the infusion rate was 0.05,0.1,0.2 and 0.5 mL/min.Compared with healthy group,spinal transection injury group had significantly shorter bladder contraction time (P < 0.05),however the relationship between bladder contraction time and infusion rate was much weakened.Spinal transaction injury rats had significantly lower peak of bladder pressure (P < 0.05) compared with healthy rats.There was no significant difference for contraction durations between the two groups.Conclusions The infusion rates influenced the contraction periods for both healthy and spinal cord injured rats.During bladder infusions with a same rate,the contraction time and the peak of bladder pressure were determined by bladder conditions,i.e.healthy or neurogenic with spinal cord injury.
3.Report of a case with Schwardz-Jampel syndrome.
Rong QIANG ; Hui-ping SHI ; Wei YU
Chinese Journal of Pediatrics 2003;41(6):456-456
Child
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Humans
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Karyotyping
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Male
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Osteochondrodysplasias
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classification
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diagnosis
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genetics
5.Metatropic dwarfism in a case.
Ji HUANG ; Li-fu GUAN ; Hui-ping SHI ; Wei YU
Chinese Journal of Pediatrics 2003;41(4):310-310
6.Kinematics Modeling and Analysis of Central-driven Robot for Upper Limb Rehabilitation after Stroke.
Jinhua YI ; Hongliu YU ; Ying ZHANG ; Xin HU ; Ping SHI
Journal of Biomedical Engineering 2015;32(6):1196-1201
The present paper proposed a central-driven structure of upper limb rehabilitation robot in order to reduce the volume of the robotic arm in the structure, and also to reduce the influence of motor noise, radiation and other adverse factors on upper limb dysfunction patient. The forward and inverse kinematics equations have been obtained with using the Denavit-Hartenberg (D-H) parameter method. The motion simulation has been done to obtain the angle-time curve of each joint and the position-time curve of handle under setting rehabilitation path by using Solid Works software. Experimental results showed that the rationality with the central-driven structure design had been verified by the fact that the handle could move under setting rehabilitation path. The effectiveness of kinematics equations had been proved, and the error was less than 3° by comparing the angle-time curves obtained from calculation with those from motion simulation.
Biomechanical Phenomena
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Humans
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Models, Biological
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Robotics
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Stroke Rehabilitation
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Upper Extremity
7.Research on Barrier-free Home Environment System Based on Speech Recognition.
Husheng ZHU ; Hongliu YU ; Ping SHI ; Youfang FANG ; Zhuo JIAN
Journal of Biomedical Engineering 2015;32(5):1019-1025
The number of people with physical disabilities is increasing year by year, and the trend of population aging is more and more serious. In order to improve the quality of the life, a control system of accessible home environment for the patients with serious disabilities was developed to control the home electrical devices with the voice of the patients. The control system includes a central control platform, a speech recognition module, a terminal operation module, etc. The system combines the speech recognition control technology and wireless information transmission technology with the embedded mobile computing technology, and interconnects the lamp, electronic locks, alarms, TV and other electrical devices in the home environment as a whole system through a wireless network node. The experimental results showed that speech recognition success rate was more than 84% in the home environment.
Computers
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Disabled Persons
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Humans
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Speech Recognition Software
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Wireless Technology
8.A case of neonatal protein C deficiency.
Yu BAO ; Li-ping SHI ; Xiu-jing WU
Chinese Journal of Pediatrics 2011;49(5):390-391
9.Investigation and analysis of professional ethics of clinical medical postgraduates
Ping ZHANG ; Xing WU ; Jiaao YU ; Shi TANG ; Baorong CHI
Chinese Journal of Medical Education Research 2017;16(5):537-540
Objective To understand the cognition of clinical medical postgraduates' professional ethics,in order to provide the basis for the further development of graduate professional ethics education.Methods The survey was carried out among 650 graduate students of the first hospital of Jilin University by self-designed questionnaires.The questionnaires included the general situation and the understanding of professional ethics of medicine.All data were analyzed by SPSS 17.0,using Chi-square test to compare the results in different grades about the understanding of professional ethics.Results In this study,a total of 650 questionnaires were issued,and 629 valid questionnaires were collected with a recovery rate of 96.7%.Most graduates' professional values were in line with the socialist core values.For example,for the attitude of medical workers to accept red envelopes,410 graduate students (65.2%) firmly opposed to accepting this behavior.For the purpose of the study medicine,there was no statistically significant difference among different grades (P=0.273).For the attitude of red paper,the main problem in medical ethics education and the biggest factor for graduates,there was statistically significant difference among different grades (P=0.012,P=0.002,P=0.002,respectively).Conclusion At present,the professional ethics of postgraduates in clinical medicine is in good condition,but still needs to be improved.We can give further education and guidance to students for the problems existing in graduate students of different grades.
10.Separate purification and directed differentiation potency of pancreatic stem cells of adult rats in vitro
Guangjun SHI ; Lei ZHANG ; Ping XU ; Jiang YU
Chinese Journal of Pancreatology 2010;10(4):260-262
Objective To investigate the experimental condition of separate purification and directed differentiation potency of pancreatic stem cells of adult rats in vitro. Methods The pancreas of adult rats were digested by collagenase V in situ perfusion. Filtration was performed by 100 mesh filter. Ficoll 400 density gradient centrifugation was used to separate pancreatic stem cells and stem cells were for cultivation. Epidermal growth factor (EGF), fibroblast growth factor (bFGF) was added to medium for in vitro cultivation.Immunofluorescence staining method was used to detect the expression of CK19, Pdx-1, nestin, insulin and glucagon, and the positive cell rate was calculated. The differentiated cell was evaluated by dithizone (DTZ)staining; insulin excretion function was determined by optical enzyme labeled ELISA staining. Results The pancreatic stem cell obtained from the study could be cultivated in vitro for 8 generations. The expression of CK19, Pdx-1 and nestin of the tem cells were all positive, and the rate of positive cells were (88.6 ± 6.2)% ,(84.6 ±8.6)% and (81.3 ±7.5)%. The differentiated cell was in brownish red color by DTZ dye. After high concentration sugar stimulation, the expression of insulin secretion was increased in the supernatant.Conclusions This method can harvest highly purified, and large amount of pancreatic duct stem cell.Artificial induction may result directed differentiate for islet-like clusters and have insulin secrete function.