2.Contrast study on the effects of autologous bone marrow mononuclear cells transplantation on myocardial infarct size
Hua ZHANG ; Xianzhong SONG ; Junsheng WANG ; Yizhang ZHENG ; Fangtao SHI
Chinese Journal of Postgraduates of Medicine 2010;33(29):16-19
Objective To study the effects ofautologous bone marrow mononuclear cells (BMMCs)transplantation during coronary artery bypass gafting (CABG) on myocardial infarct size. Methods Forty myocardial infarction patients diagnosed by coronary angiography (CAG) and SPECT and confirmed at surgery were enrolled and randomly assigned CABG alone (group Ⅰ) or CABG with intramyocardial or intracoronary injection of autologous BMMCs (group Ⅱ), 20 cases in each group. Baseline and followed up evaluations included SPECT and NYHA-FC before and after 6 months operation, recorded the major adverse cardiac events (MACE) at the same time. The number of autologous BMMCs injected was (6.84 ± 2.88) ×107 in group Ⅱ. Results There was no procedure-related complication during 6 months followed up in all patients. After 6 months operation,left ventricular ejection fraction in group Ⅱ was significantly higher than that in group Ⅰ [(57.40 ±5.21)% vs. (50.75 ±5.88)%,t =3.79,P<0.05],NYHA-FC in group Ⅱ was significantly improved than that in group Ⅰ [(1.30 ± 0.47) grades vs. (1.85 ± 0.59) grades, t = 3.27, P <0.05],SPECT showed myocardial infarct size in group Ⅱ was significantly lower than that in group Ⅰ[(14.57 ±5.20)% vs. (20.45 ±5.18)% ,P <0.05]. Conclusion Autologous BMMCs transplantation during CABG is safe and feasible, which can reduce the myocardial infarct size in patients with myocardial infarction.
3.Allogeneic cord blood hematopoietic stem cell transplantation in two cases of children with leukemia.
Yong-min TANG ; Hua SONG ; Shi-long YANG
Journal of Zhejiang University. Medical sciences 2007;36(6):626-628
Antineoplastic Combined Chemotherapy Protocols
;
therapeutic use
;
Child
;
Child, Preschool
;
Combined Modality Therapy
;
Cord Blood Stem Cell Transplantation
;
adverse effects
;
Female
;
Graft vs Host Disease
;
therapy
;
Humans
;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
;
therapy
;
Male
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma
;
therapy
;
Transplantation, Homologous
4.Comparison of different types of catheter treatment of anastomotic ring canalicular effect
Shu-Hong, CAI ; Shi-Hua, ZHANG ; Qing-Shan, SONG
International Eye Science 2016;16(11):2157-2159
AIM: To investigate the comparison of different types of catheter treatment of anastomotic ring canalicular effect.
METHODS:Retrospective analysis. A total of 114 cases 114 eyes were randomly selected between May 2013 to May 2015 jointly admitted to Huizhou Huizhou City People's Hospital and the Central People's Hospital of canalicular patients in accordance with the agreement of the annular catheterization divided into three groups, group A of annular nasal lacrimal duct catheterization in 36 eyes, group B for the whole nasal lacrimal annular catheterization in 33 eyes, group C between the upper annular tears point catheterization 45 eyes. Through the A, B, C three groups after 1, 3wk, 1, 3mo and 1y follow-up were analyzed to compare.
RESULTS:Group A of 31 eyes were cured, improved in 2 eyes, 3 eyes, the effective rate was 91. 7%;group B, 27 cases were cured, improved in 3 eyes, 3 eyes, the effective rate was 90. 9%;group C, 40 cases were cured, improved in 2 eyes, 3 eyes, the effective rate was 93. 3%. A, B, C three groups efficiency pointless difference (P=0. 124). Eye Effect: A, B, C meaningful difference among the three groups(F=36. 578; P=0.002), Group A scored the highest score of a minimum group C, respectively( 3. 5±0. 8 ) and ( 2. 3±0. 7 ); comparison meaningless difference between group a and group B( t=0. 086, P>0. 05 ); Group A and C and comparison of differences between group C and group B have the significance ( t = 15. 241, t = 17. 472; P<0. 05 ). Nasal influence: A, B, C meaningful difference among the three groups(F=778. 581;P=0. 001), the highest score in group B, group C minimum scores were(6. 6±0.8) and ( 0. 9 ± 0. 7 ); A, B, C three groups comparison of differences twenty-two have significance(t=17. 262; t=18.247; t = 16. 647; P<0. 05). Shape Effect: A, B, C difference among the three groups of meaningful ( F=481. 113;P=0. 002), Group A scored the highest score of a minimum group C, respectively(5. 8±0. 9) and(1. 2±0.6);Compare the difference between Groups B and C meaningless ( t = 0. 087, P > 0. 05 ); comparing the differences between the Groups A and B and between Group A and C were significance(t=26. 362, t=27. 532; P<0. 05 ). Unplug risk: A, B, C meaningful difference among the three groups(F=751. 121;P=0. 003), Group A scored the highest score of a minimum group C, respectively(6. 5±0. 7 ) and ( 1. 5±0. 7 ); A, B, C three groups comparison of differences twenty - two have significance(t=19. 642; t=20. 153; t=18. 345; P<0. 05). Group A had 8 patients had lower eyelid eversion, 5 cases of inferior lacrimal point expansion, 13 cases of sneezing, itchy nose, runny nose syndrome. Group B had 20 cases of varying degrees of now sneezing, itchy nose, runny nose syndrome. Group C had no serious complications.
CONCLUSION: Similar to A, B, C three groups of treatment efficacy, patient lacrimal functional recovery is safe and effective, which the group C treatment, during treatment and less material and fewer postoperative complications in patients, it is worth promotion.
5.Influence of nursing intervention on perioperative psychological status and treatment compliance of patients udergoing breast augmentation
Hua ZHANG ; Meihua SUN ; Hua CHEN ; Too BO ; Lanping SHI ; Chen SONG
Chinese Journal of Practical Nursing 2010;26(11):72-74
Objective To investigate the influence of nursing intervention on perioperative psychological status and treatment compliance of patients undergoing breast augmentation. Methods 82 patients were investigated with self-rating anxiety scale (SAS), self-rating depression scale (SDS), self-designed mental activity questionnaire on patients with breast augmentation. And they were divided into the intervention group(42 patients) and the control group(40 patients) randomly. The control group was given routine treatment and nursing. The intervention group received systematic nursing intervention such as psychological needs,confidentiality, the relevant specialist knowledge and explanation and prevention o complications besides routine treatment and nursing care. The perioperative psychological status and treatment efficacy were compared between the two groups. Results The worrying degree about operation - related problems was lower in the intervention group compared with that of the control group, but SAS and SDS score showed no significant difference one day before operation between the two groups. SAS and SDS score of the intervention group were improved before discharge compared with those before operation and were also better than those of the control group. Conclusions Patients undergoing breast augmentation surgery subject to a variety of perioperative psychological barriers, systematic nursing intervention can significantly improve the psychological state and treatment compliance, make them to acquire the unification of perfect body shape and psychology with best physical and mental status during perioperative stage.
6.Significance of C-reaction protein for differential diagnosis of fever after chemotherapy on children with acute lymphoblastic leukemia.
Cheng-qing FANG ; Yong-min TANG ; Hai-feng LI ; Hua SONG ; Shu-wen SHI ; Shi-long YANG ; Wei-quan XU
Chinese Journal of Pediatrics 2004;42(7):536-537
Antimetabolites, Antineoplastic
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adverse effects
;
therapeutic use
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C-Reactive Protein
;
analysis
;
Child
;
Child, Preschool
;
Cytarabine
;
adverse effects
;
therapeutic use
;
Diagnosis, Differential
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Female
;
Fever
;
blood
;
chemically induced
;
diagnosis
;
Humans
;
Infant
;
Male
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma
;
blood
;
drug therapy
;
Teniposide
;
therapeutic use
7.Influence factors on the cryosurvival rate of post-thaw spermatozoa from sperm donors.
Liang ZHOU ; Zhou ZHANG ; Juan-Zi SHI ; Xiao-Hua LIU ; Wen-Hao SHI ; Hui KOU ; Juan SONG
National Journal of Andrology 2014;20(6):523-526
OBJECTIVETo investigate the influence of seasons, blood types and semen parameters on the cryosurvival rate of frozen-thawed spermatozoa from sperm donors.
METHODSWe retrospectively analyzed the influence of seasons, blood types, abstinence period, semen volume, sperm morphology, and pre-freeze sperm motility and concentration on the cryosurvival rate of frozen-thawed sperm in 4 088 semen samples from Shaanxi Human Sperm Bank.
RESULTSThe cryosurvival rate of the post-thaw sperm was correlated negatively with the progressive motility of the pre-freeze sperm (r = -0.262, P < 0.01), but positively with pre-freeze sperm concentration (r = 0.247, P < 0.01), and it was significantly higher in the 6-day abstinence group ([70.2 +/- 5.4]%) than in the other abstinence groups (P < 0.01), so was it in the normal sperm morphology rate > 20% group ([71.4 +/- 5.1]%) than in the others (P < 0.01). The survival rate of the post-thaw sperm was not correlated with seasons, blood types, and semen volume (P > 0.05).
CONCLUSIONSperm motility, concentration and morphology and the abstinence period of sperm donors may be valuable predictors of the cryosurvival rate of post-thaw sperm, but no correlation was found between the survival rate and seasons, blood types and semen volume.
Adult ; Cryopreservation ; Humans ; Male ; Retrospective Studies ; Semen Preservation ; Sperm Motility ; Spermatozoa ; Young Adult
8.Quick diagnosis of glanzmann's thrombasthenia with flow cytometry.
Hai-dong FU ; Hong-qiang SHEN ; Bo-qin QIAN ; Yong-min TANG ; Hua SONG ; Shu-wen SHI ; Shi-long YANG
Chinese Journal of Pediatrics 2003;41(5):375-376
Child
;
Child, Preschool
;
Female
;
Flow Cytometry
;
methods
;
Humans
;
Infant
;
Male
;
Thrombasthenia
;
classification
;
diagnosis
9.Effects of different first dose calcium tetrahydro-folate on toxicity and side effects of large dose methotrexate treated standard risk group children with acute lymphoblastic leukemia.
Cheng-qing FANG ; Wei-qun XU ; Yong-min TANG ; Hua SONG ; Shuweng SHI ; Shilong YANG
Chinese Journal of Pediatrics 2004;42(5):392-393
Adolescent
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Antimetabolites, Antineoplastic
;
adverse effects
;
therapeutic use
;
Child
;
Child, Preschool
;
Drug Interactions
;
Drug Therapy, Combination
;
Female
;
Humans
;
Male
;
Methotrexate
;
adverse effects
;
therapeutic use
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma
;
drug therapy
;
Sex Factors
;
Tetrahydrofolates
;
administration & dosage
;
therapeutic use
;
Treatment Outcome