With the improvement of endoscopic technology,an increasing number of early esophageal cancer is diagnosed by gastroscopy.Regardless of the size or submucous fibrosis of esophageal cancer,endoscopic submucosal dissection (ESD) allows en bloc resection and histologically complete resection of the tumor.ESD has been recognized as an optimal treatment modality for early esophageal carcinoma.Currently,short-term curative effects of early esophageal cancer after ESD have been proved satisfactory,but the long-term outcomes remain unclear.This paper reviews the research advances about the long-term outcomes of ESD,and focuses on the postoperative stenosis,the recurrence,metastasis and survival rates of patients,to provide treatment reference for clinicians.

Objective To observe the clinical efficacy of electroacupuncture plus puncturing the thirteen ghost points in treating diabetic gastroparesis.Method Sixty patients with diabetic gastroparesis were randomized into a treatment group and a control group, 30 in each group. The treatment group was intervened by electroacupuncture plus puncturing the thirteen ghost points, while the control group was by electroacupuncture alone. The clinical efficacies were then compared.Result The total effective rate was 93.3% in the treatment group versus 83.3% in the control group, and the difference was statistically significant (P<0.05). Conclusion Electroacupuncture plus puncturing the thirteen ghost points is an effective approach in treating diabetic gastroparesis.

Objective To examine visceral fat in pathogenesis of coronary heart disease in male adults .Me thods 64-slice spiral CT were measured to separate 50 patient into the following 2 groups:CAD( n =26)and healthy control( n =24).Results Fasting insulin concentration, Insulin resistance index, cholesterol, triglyceride, waist circumference and visceral fat were higher in coronary heart disease group while the lower in healthy control group ( P <0.01 ) .The levels of fasting insulin concentration was posi-tively correlated with visceral fat ( r =0.779 , P <0.01 ) .Conclusions Coronary heart disease is characterized with insulin resist-ance.Fasting insulin concentration and visceral fat are higher in coronary heart disease group than the healthy group , and they may be involved in the pathogenesis of insulin resistance .

Cadherins that mediate the adhesion of the same type of cells by specific binding to calciumdependent adhesions of the same type with cadherins mainly consist of three subtypes including E-cadberin,P-cadherin and N-cadherin.In recent years,more and more studies have indicated that cadherins are closely related to triple-negative breast cancer(TNBC)and play an important role in prognosis and treatment of TNBC.

Pediatric severe sepsis and septic shock is one of leading causes of death in PICU.Although antibiotics and comprehensive treatments have continuous improvements,its mortality rate is still high.Present study confirms early goal-directed therapy can significantly reduce the mortality of severe sepsis and septic shock.The purpose is to introduce the early goal-directed therapy protocol and to guide Chinese pediatrician to improve outcome of pediatric severe sepsis and septic shock and increase the survival rate in clinical practice.

Caveolae is a specified micro-domain of plasma membrane, which consists of caveolin and many lipid molecules and membrane proteins. Caveolae plays important roles in internalization of extra-membrane molecules, transmembrane signal transdution and transport of cholesterin. Recent studies indicated that caveolae and its components were up-regulated in multidrug resistant tumor cells and might participate the development of multidrug resistance of tumor cells. This paper concentrated on the role of caveolae in tumor multidrug resistance.

Objective To discuss the clinical application of preoperative transcatheter arterial chemoembolization (TACE) in treating squamous cell carcinoma of tongue. Methods A total of 26 patients with pathologically proved squamous cell carcinoma of tongue were enrolled in this study. Using Seldinger technique, lingual artery angiography and TACE were carried out in all patients. Radical resection of tongue cancer was performed in 2-3 weeks after TACE. Results Super-selective catheterization and TACE was successfully accomplished in all patients. After TACE the tumor size was significantly decreased in all patients. During the operation, clear lesion's border was observed, and the amount of blood loss was less than usual. Conclusion For the treatment of squamous cell carcinoma of tongue, preoperative superselective TACE is safe and effective;it can increase the opportunity of surgical resection, reduce the surgical damage, and improve the quality of life as well as the survival rate.

OBJECTIVE To prevent clinical infection due to intravenous infusion by indwelling trocar.METHODS The methods of intravenous infusion by indwelling trocar,the location the indwelling time and the relationship of veinal infection with indwelling trocar were observed in 320 cases.RESULTS Veinal infection didn′t occur in patients who used the trocar.CONCLUSIONS The risk factors of infection due to intravenous infusion by indwelling trocar include the location of puncture,washing hands,aseptic technique,enveloping duct technique,application exchange,osmotic pressure of drug,indwelling time,operation technique,patients′ own situation and so on.Correct operation and standard management can prevent infection of intravenous infusion by inewelling trocar.

0.05);3 group of local infection,the incidence of catheter-induced bacteremia than 1,2 low(P

Objective To investigate the relationship of professional identity and social support among nursing undergraduates. Method Overall 286 nursing undergraduates participated in the survey by the professional identity scale and social support scale. Results The average score on the social support was (38.12 ± 4.70), and the average score on the professional identity of undergraduate nursing students was (107.29 ± 15.01), which was in the medium level. There was significant positive correlation between nursing undergraduates′social support and professional identity as well as other dimensions (P<0.05, P<0.01). Conclusions Nursing undergraduates′social support is closely related to its professional identity. It is suggested that the nursing undergraduates should be provided a variety of psychological and behavioral support and they should be helped to fully use social resources , so as to improve their professional identity.