Epistaxis is a common otorhinolaryngological emergency with complex etiological factors and varied clinical manifestations. The key to epistaxis treatment is accurate diagnosis and adequate hemostasis. Electrocoagulation is a reliable, safe and effective treatment for epistaxis. However, there are still several deficiencies in application of the commonly used electrocoagulation surgical products. This paper introduces a new type of radiofrequency head incorporating the dynamic circulatory functions of drip, irrigation, hemostasis and aspiration. We aim to achieve noninvasive, effective and accurate hemostasis in the treatment of epistaxis or nasal sinus surgery.
Humans ; Epistaxis/surgery* ; Electrocoagulation ; Treatment Outcome ; Paranasal Sinuses

Chronic Disease ; Humans ; Inflammation ; diagnosis ; pathology ; Nasal Mucosa ; pathology ; Paranasal Sinuses ; pathology

Objective:To examine the expression of TRAF 6 in ovarian carcinomas ,discuss the relation between expression level and clinical characteristics of ovarian carcinomas and study the clinical significance .Methods: Specimens from 102 patients with ovarian carcinomas managed in our hospital between Augest 2001 and December 2009 were included in this study .Immunohistochemical staining was used to detect the expression of TRAF 6 in ovarian carcinomas and normal tissues .All the specimens were confirmed by pa-thology for ovarian carcinomas and normal tissues by HE staining .Then, the correlation between the expression and clinical characteristics of patients was analyzed .Furthermore ,survival analyses were performed according to the Kaplan-Meier method.Results:The positive expression rate of TRAF 6 in ovarian carcinomas and normal tissues was 68.6% and 20.5%, respectively.TRAF6 expression was significantly associated with tumor stage and distant metastasis ( P<0.05 ) .According to the survival analysis of 102 ovarian carcinomas patients ,cases in the TRAF6 low-expression group showed poorer overall survival rate when compared with low -expression group ( P<0.001 ) .Conclusion: These results indicate that the expression of TRAF 6 was closely related with in the progression of ovarian carcinomas and may have clinical utility in the prediction of prognosis of ovarian carcinomas .

Objective To investigate the effect of acupuncture combined with rehabilitation on Joubert syndrome. Methods 2 infants with Joubert syndrome were reviewed. Results After the treatment of acupuncture combined with rehabilitation for 4~6 months, the clinical symptoms of these 2 cases improved, and the scores of Gross Motor Function Measure increased. Conclusion Acupuncture combined with rehabilitation is effective on Joubert syndrome.

Objective To explore the effects of curdione on cognitive function and expression of inflammatory factors in the hippocampus after partial hepatectomy in aged mice.Methods The animals were divided into control group, sham group, operation group, and high-, medium-and low-dose curdione groups.The model of partial hepatectomy in aged mice was established according to the method reported in literature.The levels of SOD, MDA, CAT and GSH-Px in the hippocampus were detected by enzyme-linked immunosorbent assay (ELISA), while the expressions of NF-κB, IL-1β, IL-6 and TNF-α were measured by Western blot.Results The escape latency was significantly increased (P<0.01), and the number of platform-site crossovers was significantly decreased in operation group (P<0.05).Compared with those in operation group, curdione significantly decreased escape latency and increased platform-site crossovers (P<0.05, P<0.05).The levels of SOD, CAT and GSH-Px in the hippocampus were significantly decreased (P<0.05) and the content of MDA was significantly increased after partial hepatectomy (P<0.01), and these were reversed by curdione (P<0.05, P<0.05, respectively).The expressions of NF-κB, IL-1β, IL-6 and TNF-α protein were significantly inhibited by curdione (P<0.05).Conclusion Curdione can significantly improve cognitive dysfunction after partial hepatectomy in aged mice and the mechanism may be related to its inhibition of oxidative stress, inhibition of NF-κB activation and reduction of inflammatory cytokines IL-1β, IL-6 and TNF-α in the hippocampus.

An analysis on the human resources, equipments and budgets of the township hospitals in Wenzhou City discovered the following setbacks: Changeable management system, poor positioning of their functionality, difficulty to play their roles, insufficient funding, inadequate infrastructure, slow development, lack of medical technicians, low level of medical services, and lack of development momentum. Based on these findings, the author proposed the following to upgrade their functionality and promote their development: Clearly positioning their functionality, improving the financial assurance mechanism, deepening system reforms in these hospitals, and further clarifying job divisions.

Aim To study the effects on T lymphocyte subsets in spleen of mice immunized with recombinant BCGSj26GST. Methods Inthe first experiment, BALB/c mice were immrnized subcutaneously by 106 and 108 CFU BCG-Sj26GST respectively. ALLthe mice were artifically challenged with cerariae of Schistosoma japonicum on 8weeks after immunization, six after challenge, the mice were killed, and the spleens were removed, cells were prepared seperately and were analysed by immunofluorescence with conjugated monoclonal antibodies in a FACsort cytofiuorimeter at 523 nm, PBS treated mice were serwed as control. In the second experiment, after immunized subcutanenously or inntraveously by 106 CFU vaccine, 4 mice were ranndonly killed to separate spleens on 0wk, 4wk, 8wk, 10wk, 14wk and 16wk after immurization, the percentage of CD+4 and CDs+ subsets was analysed as above. Results In the first experiment, CD+4 subsets increased renarkably, but CD+8 subsetsdid slightly by immunization with the vaccine against challenge with S.j. Cercariae, in the second experiment, the dynamic observation showed that in the subcutaneous and intravenous group, CD+4 subsets increased obviously since 10wk and 8wk respectively, CD8+ subsets hadno obvious changeover 16 weeks of observation , in the subcutaneous groupbuttheCD8+ subsets rose lightly on 4-16wk in the intravenous group. Conclusion On the basis of this study it's suspected that CD+4 subsets might play an important role in the protective immunity induced by the vaccine

There are not yet uniform for the recognition and morphological description of Russell bodies and Mott cells.Some difficulties for the learner in clinical diagnosis were encountered.The characteristics of name and morphology of Russell bodies and Mott cells were described in this paper combined with many years of experience in clinical practice according to new point of view of (2008) World Health Organization classification of tumours of haematopoietic and lymphoid tissues and European Leukemia Net Morphology Faculty.

To summarize the risk factor,pathogenic bacteria,medical and prevention progress of ventilator-associated pneumonia.It is beneficial to avoid the risk factor of ventilator-associated pneumonia,and to reduce morbidity and mortality.

BACKGROUND:Many researches on the development of cochlea have been made, but mainly depend on the pathological conditions and developmental deformity, while the researches on the development process of normal embryonic cochlea and expression of related factors are rare.
OBJECTIVE:To investigate the expression of transforming growth factorβ1 in rat embryonic cochlea.
METHODS:Fifty-six Sprague Dawley rats were selected and the rats were pregnancy, and the embryos were obtained from the rats, trimmed the inner ear specimens under the anatomical microscope, and then the specimens were treated with dehydration, decalcification, directly paraffin embedding and slicing processing. The morphology evolution of inner cochlea was observed under light microscope after hematoxylin-eosin staining. The expression of transforming growth factorβ1 in rat embryonic cochlea was observed by immunohistochemical streptavidin biotin-peroxidase complex method.
RESULTS AND CONCLUSION:The development of rat inner ear began in ectoderm thickening area of E8 phase, otocyst and the emergency of the mesenchymal could be seen in E9 phase, otocyst and ossicular chain began to develop in E9.5 phase, formation of cochlear duct anlage could be seen in E12.5 phase, cochlea tube development was completed in E18.5 phase and Corti’s formation could be seen in E16 phase. The structure and function of the inner ear could be ful y developed after birth. The expression of transforming growth factorβ1 could be seen in E12.5-E19 phases, and the expression was changed from weak to strong and then weakened further, and strongest in E14.5 phase. This suggested that transforming growth factorβ1 may be involved during the development of rat cochlear epithelium.