This survey was to elucidate the bacterial clearance time (BCT) among the patient of L-type and B-group leprosy who had been und.er chernotherapy and foll- ow up with bacterial examination 4 times every year more than 3 years at the Chronic Disease Laboratory of Catholic Medical College. The 99 patients, 53 L-type and 46 B-group, were slected for this study. These patients were classified again into 2 groups: 80 patients with negative bacterial index and 19 patient of posit.ive bacterial index. The patient with negative bacterial index was subdivided into 3 groups by BCT. 1. Rapid decrease group (RA group) BCT<(4years) 2. Standard decrease group (ST group) 4BCT<7 R. Slow decrease group (SL group) 7.
Chronic Disease ; Drug Therapy* ; Humans ; Leprosy* ; Leprosy, Borderline* ; Leprosy, Lepromatous* ; Prognosis*

OBJECTIVE: To evaluate the feasibility of a new position (internal rotation in hanging) in ultrasonography, we compared the length of the glenohumeral joint space and the effectiveness of steroid injection with the hanging position and with the commonly used abdomen or cross position. METHODS: A prospective, randomized controlled trial was performed in 42 patients with adhesive capsulitis of shoulder. We used three arm positions for the posterior approach as follows: the patient's palm on thigh, other hand on abdomen (abdomen position); hand on patient's opposite shoulder (cross position); arm in hanging position with internal rotation of shoulder (hanging position). The order of shoulder position was randomized and blinded. Real-time ultrasonography-guided intra-articular steroid injection was performed by posterior approach at the first position in each patient. The Brief Pain Inventory (BPI), the Shoulder Pain and Disability Index (SPADI), and range of motion (ROM) were measured before steroid injection and 2 weeks after injection. RESULTS: The lengths of the joint space were 2.88±0.75, 2.93±0.89, and 2.82±0.79 mm in abdomen, cross, and hanging position respectively, with no significant difference among the three positions (p=0.429). Treatment efficacy was significantly improved in ROM, total BPI, and SPADI in all three positions (p<0.001). The changes in ROM for shoulder abduction were 23.6°±19.7°, 22.2°±20.9°, and 10.0°±7.8° in abdomen, cross, and hanging position, respectively. Changes in total BPI scores were 25.1±15.7, 23.6.±18.0, 11.6±6.1, and changes in total SPADI score were 35.0±14.2, 30.9±28.9, and 16.5±10.3 in abdomen, cross, and hanging position, respectively. There were no significant difference among the three positions for all parameters (p=0.194, p=0.121, and p=0.108, respectively. CONCLUSION: For patients with adhesive capsulitis who cannot achieve or maintain abdomen or cross position, scanning and injection with the shoulder in internal rotation with hanging position may be a useful alternative.
Abdomen ; Adhesives* ; Arm ; Bursitis* ; Hand ; Humans ; Injections, Intra-Articular ; Joints ; Posture ; Prospective Studies ; Range of Motion, Articular ; Shoulder Joint ; Shoulder Pain ; Shoulder* ; Thigh ; Treatment Outcome ; Ultrasonography

OBJECTIVE: To evaluate the feasibility of a new position (internal rotation in hanging) in ultrasonography, we compared the length of the glenohumeral joint space and the effectiveness of steroid injection with the hanging position and with the commonly used abdomen or cross position. METHODS: A prospective, randomized controlled trial was performed in 42 patients with adhesive capsulitis of shoulder. We used three arm positions for the posterior approach as follows: the patient's palm on thigh, other hand on abdomen (abdomen position); hand on patient's opposite shoulder (cross position); arm in hanging position with internal rotation of shoulder (hanging position). The order of shoulder position was randomized and blinded. Real-time ultrasonography-guided intra-articular steroid injection was performed by posterior approach at the first position in each patient. The Brief Pain Inventory (BPI), the Shoulder Pain and Disability Index (SPADI), and range of motion (ROM) were measured before steroid injection and 2 weeks after injection. RESULTS: The lengths of the joint space were 2.88±0.75, 2.93±0.89, and 2.82±0.79 mm in abdomen, cross, and hanging position respectively, with no significant difference among the three positions (p=0.429). Treatment efficacy was significantly improved in ROM, total BPI, and SPADI in all three positions (p<0.001). The changes in ROM for shoulder abduction were 23.6°±19.7°, 22.2°±20.9°, and 10.0°±7.8° in abdomen, cross, and hanging position, respectively. Changes in total BPI scores were 25.1±15.7, 23.6.±18.0, 11.6±6.1, and changes in total SPADI score were 35.0±14.2, 30.9±28.9, and 16.5±10.3 in abdomen, cross, and hanging position, respectively. There were no significant difference among the three positions for all parameters (p=0.194, p=0.121, and p=0.108, respectively. CONCLUSION: For patients with adhesive capsulitis who cannot achieve or maintain abdomen or cross position, scanning and injection with the shoulder in internal rotation with hanging position may be a useful alternative.
Abdomen ; Adhesives* ; Arm ; Bursitis* ; Hand ; Humans ; Injections, Intra-Articular ; Joints ; Posture ; Prospective Studies ; Range of Motion, Articular ; Shoulder Joint ; Shoulder Pain ; Shoulder* ; Thigh ; Treatment Outcome ; Ultrasonography

Acute interstitial nephritis is an important cause of acute renal failure and result from immune mediated tubulointerstitial injury, initiated by medications, infections, and other variable causes. Since acute interstitial nephritis may present a variety of clinical and laboratory findings and progress more rapidly than expected and it is reversible with withdrawal of the etiologic drug or administration of steroid, its early detection is very important. Mycoplasma pneumoniae is a common pathogen in young-healthy adult but mycoplasma infection induced acute interstitial nephritis is rarely reported. Therefore considering mycoplasma infection as one possible cause of acute interstitial nephritis is clinically important. So we report a case of acute interstitial nephritis associated with mycoplasma infection.
Acute Kidney Injury ; Adult ; Humans ; Mycoplasma Infections ; Mycoplasma pneumoniae* ; Mycoplasma* ; Nephritis, Interstitial* ; Pneumonia, Mycoplasma*

AIM: To assess the efficacy of cyanoacrylate adhesive in the management of large perforations of the maxillary sinus membrane during sinus lifts. MATERIAL AND METHODS: Eight rabbits were used in the study. Sinus membrane perforation(about 1.5cm) was repaired with cyanoacrylate adnesive on one side of the maxillary sinus and the opppsite side was used as a control. Histological evaluation was performed 4 weeks after the operation. RESULTS: Histological studies showed normal healing of the sinus membrane across the site of previous perforation and no evidence of inflammation. CONCLUSION: Our results support the clinical use of cynoacrylate adhesive for repairing sinus membrane perforation.
Adhesives* ; Cyanoacrylates* ; Inflammation ; Maxillary Sinus ; Membranes* ; Rabbits

The role of cultured bone marrow stromal cells (BMSCs) in peripheral nerve regeneration was examined using an established rabbit peroneal nerve regeneration model. A 15-mm peroneal nerve defect was bridged with a vein filled with BMSCs (1 x 10(6)), which had been embedded in collagen gel. On the contralateral side, the defect was bridged with a vein filled with collagen gel alone. When the regenerated tissue was examined 4, 8 and 12 weeks after grafting, the number and diameter of the myelinated fibers in the side with the BMSCs were significantly higher than in the control side without the BMSCs. This demonstrates the potential of using cultured BMSCs in peripheral nerve regeneration.
Bone Marrow* ; Collagen ; Mesenchymal Stromal Cells* ; Myelin Sheath ; Peripheral Nerves* ; Peroneal Nerve ; Regeneration* ; Transplants ; Veins

Shoulder pain presents with varying etiology and pathophysiology. At the time of initial evaluation, conservative management is applied in most cases. The therapeutic approach should be based on the cause of pain, which should be determined by the appropriate evaluation. Recovery of range of motion, strengthening of rotator cuffs and other shoulder muscles, and scapular stabilization are the main principles and purposes of shoulder rehabilitation. In this article, we introduce diagnosis-specific management approaches for common presentations of shoulder pain such as adhesive capsulitis, impingement syndrome or rotator cuff tendinosis, and calcific tendinitis.
Bursitis ; Muscles ; Range of Motion, Articular ; Rehabilitation ; Rotator Cuff ; Shoulder ; Shoulder Pain* ; Tendinopathy

Shoulder pain presents with varying etiology and pathophysiology. At the time of initial evaluation, conservative management is applied in most cases. The therapeutic approach should be based on the cause of pain, which should be determined by the appropriate evaluation. Recovery of range of motion, strengthening of rotator cuffs and other shoulder muscles, and scapular stabilization are the main principles and purposes of shoulder rehabilitation. In this article, we introduce diagnosis-specific management approaches for common presentations of shoulder pain such as adhesive capsulitis, impingement syndrome or rotator cuff tendinosis, and calcific tendinitis.
Bursitis ; Muscles ; Range of Motion, Articular ; Rehabilitation ; Rotator Cuff ; Shoulder ; Shoulder Pain* ; Tendinopathy

The F wave has been thought to be useful in assessing the proximal neuropathy such as radiculopathy. However the sensitivity of F wave in radiculopathy is varying from 18% to 65%. The aim of this study is to compare the relative diagnostic value of 20 averaging technique and 20 sequential stimulation technique in recording the F waves and to determine the usefulness of F wave for the evaluation of radiculopathy. Animals employed were rabbits that were divided into a study group of 17 rabbits(31 legs) and control group of 14 rabbits(25 legs). In the study group, the sciatic nerve was exposed after the dissection of gluteus maximus muscle and the nerve trunk was traced up to reach the spinal canal level. One of the two nerve roots composing the sciatic nerve was dissected randomly. F wave parameters were measured using both of 20 averaging technique and 20 sequential stimulation technique. The parameters which showed significant change after the root dissection were the amplitude by employing 20 electronic averaging technique, and mean latency, minimal latency, mean amplitude by employing 20 sequential stimulation technique. We concluded that 20 electronic averaging technique had no benefit over the 20 sequential stimulation technique and F wave measurement was not useful for the electrodiagnosis of radiculopathy because of the wide range of control values.
Animals ; Electrodiagnosis ; Rabbits ; Radiculopathy* ; Sciatic Nerve ; Spinal Canal

Balloon eustachian tuboplasty (BET), a surgical technique to expand the cartilaginous portion of the eustachian tube by ballooning via opening at the nasopharynx, has been introduced as a useful surgical modality for eustachian tube dysfunction patients. Although BET is known as a relatively safe procedure, we recently have experienced two cases of cardiac complications during balloon inflation. In one case, an asystole occurred for 13 seconds during this procedure; the heart rate was recovered after balloon deflation with an intravenous injection of glycopyrrolate and atropine. In the other case, bradycardia occurred and continued during BET. Heart rate was recovered immediately after deflation of balloon without drug injection. As far as we know, this is the first report of cardiac complications during BET, probably related with trigemino-cardiac reflex. In both cases, no other sequelae remained after the surgery. We report these two cases of cardiac complications that occurred during BET along with a review of literature.