1.Noninvasive follicular thyroid neoplasm with papillary-like nuclear features and the risk of malignancy in thyroid cytology: Data from Singapore.
Bryan Wei Wen LEE ; Manish Mahadeorao BUNDELE ; Rong TAN ; Ernest Wei Zhong FU ; Agnes Siqi CHEW ; Junice Shi Hui WONG ; Caroline Ching Hsia SIEW ; Brenda Su Ping LIM ; Rinkoo DALAN ; Ming Yann LIM ; Yijin Jereme GAN ; Hao LI
Annals of the Academy of Medicine, Singapore 2021;50(12):903-910
INTRODUCTION:
The impact of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) on the risk of malignancy (ROM) in fine-needle aspiration cytology (FNAC) per The Bethesda System for Reporting Thyroid Cytopathology has not been well reported in Singapore.
METHODS:
We retrospectively identified 821 thyroid nodules with preoperative FNAC from 788 patients out of 1,279 consecutive thyroidectomies performed between January 2010 and August 2016 in a tertiary general hospital in Singapore. Possible cases of NIFTP were reviewed for reclassification and the impact of NIFTP on ROM was analysed.
RESULTS:
The incidence of NIFTP was 1.2% (10 out of 821). If NIFTP is considered benign, ROM in Bethesda I through VI were 8.6%, 3.5%, 26.3%, 20.0%, 87.7%, 97.0% versus 8.6%, 4.2%, 28.1%, 26.7%, 89.2% and 100% if NIFTP is considered malignant. Eight patients with NIFTP had follow-up of 15 to 110 months. One had possible rib metastasis as evidenced by I131 uptake but remained free of structural or biochemical disease during a follow-up period of 110 months. None had lymph node metastasis at presentation, nor locoregional or distant recurrence.
CONCLUSION
Classifying NIFTP as benign decreased ROM in Bethesda II through VI, but the benignity of NIFTP requires more prospective studies to ascertain. The impact of NIFTP on ROM in our institution also appears to be lower than that reported in the Western studies.
Adenocarcinoma, Follicular/epidemiology*
;
Humans
;
Prospective Studies
;
Retrospective Studies
;
Singapore/epidemiology*
;
Thyroid Neoplasms/epidemiology*
2.Factors influencing the decision to pursue emergency medicine as a career among medical students in Singapore.
Shi Hao CHEW ; Irwani IBRAHIM ; Yan Zhen YONG ; Lu Ming SHI ; Qi Shi ZHENG ; Dujeepa D SAMARASEKERA ; Shirley Beng Suat OOI
Singapore medical journal 2018;59(3):126-132
INTRODUCTIONThe introduction of the residency programme in Singapore allows medical students to apply for residency in their graduating year. Our study aimed to determine the interest levels and motivating factors for pursuing emergency medicine (EM) as a career among medical students in Singapore.
METHODSA self-administered questionnaire was distributed to Year 1-5 medical students in 2012. Participants indicated their interest in pursuing EM as a career and the degree to which a series of variables influenced their choices. Influencing factors were analysed using multinomial logistic regression.
RESULTSA total of 800 completed questionnaires were collected. 21.0% of the participants expressed interest in pursuing EM. Perceived personality fit and having done an elective in EM were strongly positive influencing factors. Junior medical students were more likely to cite the wide diversity of medical conditions and the lack of a long-term doctor-patient relationship to be negative factors, while senior medical students were more likely to cite personality fit and perceived prestige of EM as negative factors.
CONCLUSIONCareful selection of EM applicants is important to the future development of EM in Singapore. Our study showed that personality fit might be the most important influencing factor in choosing EM as a career. Therefore, greater effort should be made to help medical students explore their interest in and suitability for a particular specialty. These include giving medical students earlier exposure to EM, encouraging participation in student interest groups and using appropriate personality tests for career guidance.
Career Choice ; Decision Making ; Emergency Medicine ; education ; manpower ; Female ; Humans ; Internship and Residency ; Male ; Motivation ; Regression Analysis ; Singapore ; Students, Medical ; Surveys and Questionnaires