The paper analyzes the challenge of big data environment to the traditional medical information services,presents the practical significance and basis of constructing the medical information service platform,introduces the construction objectives,architecture,function feature of the platform,describes the medical information service mode based on the digital platform,including medical information resource services,intelligence study services and health decision-making support services,etc.

There are a variety of surgical treatments of advanced esophagogastric junction cancer,type Ⅰ 、Ⅱ mainly by transthoracic approach,part of the type Ⅱ by transabdominal approach,type Ⅲ mainly by left thoracoabdominal approach (LTA) or transabdominal.Intraoperative lymph node dissection is one of the most important factors which affect the postoperative survival rate.The cardia right lymph node (NO.1),the cardia left lymph node (NO.2),gastric lesser curvature (NO.3) and left gastric artery side (NO.7) should do regular cleaning.

Objective To analyze depressive symptoms and its relationship with cognitive function of elderly patients in mental hospital.Methods To investigate 221 cases of elderly patients aged more than 60 years old selected from Yiwu third people's hospital and were screened by Chinese version of center of epidemiological survey depression scale (CES-D) and Chinese version of mini-mental states examination (MMSE).Results (1)153 cases (69.2%) of elderly patients suffer from definite depression symptoms.(2) The depressive symptoms of elderly patients,with different age,sex,educational level,have no significant difference.(3)The depressive symptoms have relationship with their cognitive function impairment on elder patients.Conclusion Routine screening for depressive symptoms and cognitive function is necessary for elderly patient with depressive or cognitive function impairment.

0 but was obviously lower than P_ sys in no endoleak. P_ sac approached P_ sys in type Ⅰ and type Ⅳ endoleaks. Some researches showed that P_ sac in type Ⅱ endoleak was higher than that in no endoleak and even approached P_ sys , however the other researches showed that P_ sac in type Ⅱ endoleak was lower than that in no endoleak. Conclusion Postoperative P_ sac dropping greatly eliminated the risk of aneurysm rupture, which symbolized the success of endovascular therapy. Even if the type Ⅰ endoleak of small size might lead to obvious elevation of P_ sac , which necessitates management. The impairment and management tactics of type Ⅱ endoleak remained equivocal, which required further study.

Objective To design a mandibular protraction appliance and to observe its effect in the treatment of mandibular retrognathia with malocclusion of Angle class II and division I. Methods 30 cases of mandibular retrognathia with Angle class II and division I malocclusion were treated with the mandibular protraction and edgewise appliance. Cephalometric radiograph and measurement were taken before and after treatment. Statistical analysis were performed. Results After treatment, maxillary and mandibular anterior teeth were arranged in dental arch neatly. Molar relationship and overjet and overbite were returned normal. SNB, ANB angle and Co-Po, Iis-SP, Mis-SP were remarkably changed. Conclusion The mandibular protraction appliance is an orthopedic force applicance. It can effectively induce forward movement of mandible and in the meantime restrain maxillary growth. It is feasible for the treatment of mandibular retrognathia.

An analytical method was developed for determination of P and Si in edible vegetable oil using inductively coupled plasma-tandem mass spectrometry (ICP-MS/MS).The microwave-assisted acid digestion of vegetable oil using HNO3 + H2O2 was carried out in closed vessels.The mass spectral interferences were eliminated by O2 mass shift when promoting reaction with O2 inside the collision reaction cell (CRC), and the monitoring of P as 31P16O+ product ion significantly improved the accuracy of the analysis.H2 was added into the CRC for H2 on-mass reaction.The interferences were eliminated by the quadrupole analyzer to accurately identify 28Si+.The effects of the flow rate of O2 and H2 in ORS3 on the signal intensities and BECs of 31P16O+ and 28Si+ were investigated.The optimum O2 and H2 flow rate was determined.Under the optimized conditions, the limits of detection were 0.043 and 0.66 μg/L for 31P16O+ and 28Si+, respectively.The accuracy of the analytical method was assessed by the analysis of the standard reference materials lubricant oil (SRM 1848) from the National Institute of Standard and Technology.No significant differences were observed between the certified values and measured values.This method was used to analyze 5 kinds of edible vegetable oils (rapeseed oil, sunflower oil, peanut oil, corn oil and soybean oil) from different regions of China, and it was found that the content of P was the highest in peanut oil, and Si showed the highest content in soybean oil.

Objective To explore different doses of recombinant tissue-type plasminogen activator (rt-PA) intravenous thrombolytic therapy for acute cerebral infarction.Methods 130 patients with acute cerebral infarction were as the research subjects selected from May 2014 to May 2015 for rt-PA thrombolytic therapy, who were divided into two groups according to rt-PA thrombolytic agent dose, 65 cases in each group.Evaluated the clinical efficacy of thrombolytic therapy after treatment in accordance within 24 h intracerebral hemorrhage (ICH) , symptomatic intracerebral hemorrhage (SICH) , other bleeding symptoms and for 3 months after treatment the prognosis was good rate, total mortality.For pre-treatment, the degree of defect nerve function after two groups of patients were scored by NIHSS score, correlation analysis between the two groups of clinical efficacy and function of the degree of nerve defect before treatment.Results 3 months after thrombolysis total mortality in the standard dose group was significantly higher than that in the low-dose group (P<0.05) .After treatment, both groups NIHSS scores were significantly lower than before treatment (P<0.05); After treatment, NIHSS score 4-8 points in the proportion of low-dose group was significantly more than that in the standard dose group (P<0.05); NIHSS score 9-16 points, 17-24 points in the proportion of low-dose group were significantly less than that in the standard dose group (P<0.05).NIHSS9-16 points of patients after total mortality three months in the standard-dose group was significantly higher than that in the low-dose group (P<0.05) . Conclusion Different doses of rt-PA thrombolytic therapy in acute cerebral infarction are basically the same, and the degree of neurological deficit does not affect the efficacy, but reduce mortality in patients 3 months after low-dose rt-PA treatment, it is worth widely used in clinical practice.

Intravenous immunoglobulin(IVIG) contains multiple-antigen-specific IgGs and may protect the host from a wide spectrum of pathogens including but not limited to virus and bacteria.With a low IgG level, neonates, especially preterm infants are prone to infection.IVIG can rapidly increase the concentration of serum IgG level, and enhance the anti-infectious and immune-regulatory functions.It has been widely used as a common treatment against neonatal infections.However, there has been inadequate evidence to support the routine usage of IVIG.While prolonged IVIG usage may be beneficial to the extremely or very low birth weight with sepsis, the prophylactic usage of IVIG to decrease the risk of late-onset sepsis in preterm infants depends on the situation of nosocomial infections in different NICUs and the cost-effect efficiency.

A questionnaire survey on awareness of child health management was conducted in 238 family members ( 236 were parents) of children aged 0 - 36 months; among whom 92 of children aged 0 to 6 months,85 of children aged 7 to 12 months,33 of children aged 13 to 18 months,16 of children aged 19 to 24 months and 12 of children aged 24 to 36 months.52.1％ of the surveyees had college education level.The awareness about medical examination in last half year in female subjects was higher than males ( P ＜ 0.05).There were no differences in other health management knowledge.The results showed that the average times of medical examination was 2.8 ± 1.9 in last half year; the age for supplement of meat in food was 7.4 ± 2.4 mouths; supplement of meat,animal liver and eggs was more than 7 time a week.The subjects with college education or above paid more attention to the children's growth,risk for rickets and anemia than other peoples.Pure breast feeding accounted for only 37.0％ (88/238).The study indicates that strengthening the knowledge and awareness is necessary to improve the children health management.