Objective To explore the effective therapeutic methods for hepatolithiasis.Methods We retrospectively analyzed the clinical material of 89 hepatolithiasis patients who underwent surgical therapy.Among the 89 patients,53 patients were treated with T-tube drainage(including 3 patients with left hepatic lobe or quadrate lobe resection),and 36 patients were treated with bile duct-intestinal anastomosis(including 6 patients with left hepatic lobe or quadrate lobe resection).Results Recurrence rate of postoperative angiocholitis in the two groups was 50.0% and 22.2% respectively,and the reoperation rate was 28.0% and 8.3% respectively.Conclusion The key to prevent recurrent angiocholitis and reduce the reoperation rate is to relieve biliary tract stricture,remove the focus of infection and provide unobstructed bile duct drainage.