1.Effectiveness of oral care with chlorhexidine in preventing ventilator-associated pneumonia: a Meta-analysis
Chinese Journal of Practical Nursing 2015;31(4):277-282
Objective We aimed to evaluate the correlation of oral care with chlorhexidine on the incidence of ventilator-associated pneumonia.Methods The PubMed,Medline,Cochrane Library,CNKI,VIP,Wanfang database until December 2013 about the clinical randomized controlled trials (RCT) of the oral care with chlorhexidine on the incidence of ventilator-associated pneumonia were searched.Software for data analysis was RevMan5.2.Results Finally 15 RCTs involving 2 615 patients were included.In 15 articles the experimental group used chlorhexidine solution or gel for oral nursing involving 1 319 cases,the control group with a total of 1 296 cases,used placebo for oral nursing involving 459 cases,837 cas-es used 0.9% saline solution or sterile water.Results of Meta-analysis indicated that there were 11.30% (149/1 319)patients with VAP in the experimental group,20.29% (263/1 296) patients in the control group.The VAP incidence between two groups had significantly statistical difference [OR=0.48,95% confidence intervals (CI) was from 0.34 to 0.67,P < 0.01].The incidence of VAP in oral care with chlorhexidine solution group (no tooth brushing) was 12.23% (80/654),in the control group the incidence of VAP was 25.44% (172/676),there was significantly statistical difference between two groups [OR=0.36,95%CI was 0.27 to 0.50,P < 0.01].The incidence of VAP in oral care with chlorhexidine gel group (no tooth brushing) was 10.47% (27/258),in the control group the incidence of VAP was 15.36% (41/267),no statistical difference showed by comparison of two groups [OR =0.65,95% CI was 0.39 to 1.09,P > 0.05].The incidence of VAP in oral care with chlorhexidine solution group (tooth brushing) was 10.32%(42/407),in the control group the incidence of VAP was 14.16% (50/353),there was significantly statistical difference between two groups [OR=0.55,95% CI 0.34 to 0.90,P<0.05].Conclusions Oral care with chlorhexidine solution (tooth brush-ing or no tooth brushing) can effectively reduce the incidence of ventilator associated pneumonia.There was no sufficient evidence to indicate that using chlorhexidine gel (no tooth brushing) for oral care can reduce the incidence of ventilator associated pneumonia.
2.Prevalence and influencing factors of colorectal polyps in Lanxi residents
Weifang ZHENG ; Xiaodong HU ; Zihan YIN ; Zhonghua LU ; Shengzhi WU ; Zhong SHEN ; Menghan JIA ; Chen WEI ; Xiangyang ZHANG
Journal of Preventive Medicine 2019;31(4):341-345
Objective:
To investigate the epidemic status and influencing factors of colorectal polyps among urban residents in Lanxi.
Methods:
A representative urban community was selected from Lanxi. A total of 935 local residents aged 18-80 years received questionnaire survey,physical examination,laboratory tests and colonoscopy. Multivariate Logistic regression analysis was applied to exam the potential influencing factors for colorectal polyps.
Results :
Eventually 880 residents were involved into the statistical analysis. Colorectal polyps were detected in 167 participants with a crude prevalence of 18.98% and adjusted prevalence for age and gender of 13.28%. The prevalence of colorectal polyps in men(28.70%)was significantly higher than that in women(12.92%,P<0.05). The results of logistic regression analysis showed that age(OR=1.038,95%CI:1.018-1.057),males(OR=1.919,95%CI:1.303-2.826),the middle school level of education(OR=2.443,95%CI:1.507-3.961)and constitution of Yin-Asthenia(OR=0.203,95%CI:0.057-0.720)were influencing factors for colorectal polyps;among male participants,hypertension(OR=1.721,95%CI:1.018-2.908)was a risk factor for colorectal polyps;among female participants,age(OR=1.076,95%CI:1.042-1.111),BMI(OR=1.099,95%CI:1.001-1.207),the middle school level of education(OR= 3.507,95%CI:1.794-6.856)and constitution of Yin-Asthenia(OR=0.160,95%CI:0.033-0.770)were influencing factors for colorectal polyps.
Conclusion
Age,sex,education level and constitution of Yin-Asthenia were associated with the risk of colorectal polyps among residents in Lanxi;hypertension was associated with the risk of colorectal polyps in males,while age,BMI,education level and constitution of Yin-Asthenia were associated with the risk of colorectal polyps in females.