1.The distribution and influential factors of exam results in medical students' general surgery theory course
Shengyi WANG ; Wei LEI ; Zhiwu CHEN ; Han HAN ; Yi LIU
Chinese Journal of Medical Education Research 2014;13(12):1283-1286
Objective To analyze the distribution and influential factors of exam results in medical students' general surgery theory course.Methods 171 medical students were selected as subjects by cluster sampling,and the distribution and influential factors of exam results were analyzed.SPSS 17.0 software was used for statistical analysis,measurement data with (-x) ± s,and normality test with Kolmogorov-Smirnov test.Those quantitative data which do not meet the normal distribution were compared with Mann-Whitney U and Kruskal-Wallis H test.Rank transformation univariate multi-factor variance of LSD (Levene test equal error variance between groups) or Tamhane method (Levene test range error variance between groups) were compared between two groups(3-4) and the influence factors of whether the grade was good was analyzed by single factor and multi factor non conditional Logistic regression model,with the test level of alpha=0.05.Results The distribution of total exam results was normal.77 score was outlier,and the scores of female students were higher than those of male students.Scores of total exam results,multiple-choice questions and essay questions in different classes were significantly different.Data from multivariate logistic regression analysis showed that male students(OR=0.212,95%CI:0.077-0.584) were unfavorable factor for good exam results,while higher scores in noun explanation (OR=12.160,95%CI:1.985-74.495),multiple-choice questions (OR=9.887,95%CI:2.997-32.617),essay questions(OR=18.323,95%CI:6.593-50.928) were favorable factors.Conclusion The cause analysis of score's outlier and sex difference should be strengthened,and the influence of examination items on score should be emphasized.
2.Lianling Formula (连苓方) Combined with Topical Tacrolimus for Atopic Dermatitis in Adolescents with Heart Fire and Spleen Deficiency Syndrome:A Randomized Controlled Trial
Ziyi FAN ; Zhanxue SUN ; Huili ZHANG ; Linxian LI ; Shengnan MA ; Shengyi LEI ; Lili ZHANG
Journal of Traditional Chinese Medicine 2024;65(23):2442-2449
ObjectiveTo evaluate the clinical effectiveness and safety of Lianling Formula (连苓方) in the treatment of adolescent atopic dermatitis (AD) exacerbation stage with heart fire and spleen deficiency syndrome. MethodsNinety-two patients were randomly divided into a treatment group and a control group, with 46 cases in each group. Patients in the control group took oral ebastine tablets, and patients in the treatment group took Lianling Formula orally, and both groups used 0.03% topical tacrolimus for 4 weeks. Before and after treatment, the improvement of scoring atopic dermatitis index by 50% (SCORAD50) and 75% (SCORAD75), scoring atopic dermatitis index (SCORAD), visual analog scale (VAS), traditional Chinese medicine (TCM) symptom score, the children's dermatology life quality index (CDLQI), Athens insomnia scale (AIS) score of both groups were evaluated, and the adverse reactions in both groups were recorded. ResultsFour cases in the treatment group and five cases in the control group were dropped, and intention-to-treat analysis was used. Finally 46 cases in each group were included in the statistics. The SCORAD scores after treatment were lower than those before treatment, and the scores in treatment group were lower than those of the control group (P<0.01); the attainment rates of SCORAD50 and SCORAD75 after treatment in the treatment group were 80.43% and 47.83%, which were significantly higher than those in the control group of 63.04% and 26.09%, respectively (P<0.05). VAS scores, TCM symptom scores, CDLQI scores, and AIS scores were lower than those before treatment (P<0.01), and VAS scores, TCM symptom scores, and CDLQI scores of the treatment group were lower than those of the control group after treatment (P<0.05 or P<0.01), while AIS scores were higher than those of the control group (P<0.05). The erythema, papule/edema, oozing/crusting, epidermal peeling, and dryness in the SCORAD scores of the treatment group after treatment were lower than those before treatment (P<0.05 or P<0.01), and the erythema, papule/edema, oozing/crusting, and dryness of children in the control group were lower than those before treatment (P<0.05 or P<0.01). The scores of erythema, oozing/crusting, and epidermal peeling in the treatment group after treatment were all lower than those in the control group (P<0.05). The scores of vexation, itching, dry mouth, poor appetite and irregular bowel movements in terms of TCM symptoms in the treatment group after treatment were lower than those before treatment (P<0.01), and the scores of itching, vexation, dark urine in the control group were lower than those before treatment (P<0.05 or P<0.01). The scores of itching, dry mouth, poor appetite, irregular bowel movements, and dark urine in the treatment group after treatment were all lower than that in the control group (P<0.05 or P<0.01). No adverse reactions occurred in both groups of children during treatment. ConclusionLianling Formula combined with topical tacrolimus can effectively improve the clinical symptoms of adolescent AD exacerbation with heart fire and spleen deficiency syndrome, and the formula is effective and safe in improving the children's skin lesions, reducing itching, relieving the accompanied TCM symptoms, and improving the quality of life.