Objective To analyze the fungal distribution and drug sensitivity analysis in 113 cases of lesion secretions .Methods Identification of fungi and drug sensitive test were done in 113 cases of lesion secretions .Results Among the 113 cases of lesion se-cretions ,there were Candida albicans 75 cases(66 .4% ) ,Candida dublin 29 cases(26 .7% ) ,Candida parapsilosis 6 cases(5 .3% ) , Candida krusei 3 cases(2 .7% ) .For Candida albicans ,the drug sensitive rates of 5-fluorocytosine and amphotericin B were 94 .7%and 97 .3% respectively .For Candida dublin ,the drug sensitive rate of amphotericin B was 93 .1% .For Candida parapsilosis ,the drug sensitive rates of voriconazole and amphotericin B were both 83 .3% .For Candida krusei ,the drug sensitive rates of 5-fluoro-cytosine and amphotericin B were both 100 .0% .Conclusion Strengthening the fungal distribution and drug sensitivity analysis be-fore treatment in fungal lesion secretions may provide direction for the clinical treatments .

The mini-midline catheter is a new technology for catheter placement that opens up a new field of peripheral venous access devices(PVADs)and plays an important role in the intravenous treatment of patients with fragile vasculature and difficult intravenous access(DIVA).Mini-midline catheter is more economical and easier to puncture than midline catheter,longer retention time than short cannula,lower catheter-related complications,it is the preferred solution for venous vascular access device(VAD)in short-to medium-term infusion and has been widely used in intravenous infusion abroad.Domestic research and application of this technology are still in the exploratory stage,and the specifications,guidelines and expert consensus for mini midline catheters have not yet been released,and there is a lack of standardized operation procedures,indications,contraindications and other guidelines.More studies with higher quality and multi-center linkage cooperation need to be carried out to provide a theoretical and practical basis for the formulation of industry standards for mini midline catheters in line with clinical practice.The definition,attributes,innovation,indications,advantages and disadvantages of the mini midline catheter were reviewed,so as to provide reference for clinical application.