1.Observations on the Efficacy of Shoulder-three-points Warm Needling Moxibustion plus Conventional Rehabilitation in Recovery from Rotator Cuff Repair
Shengjun ZHANG ; Fengfan SUN ; Fu XU
Shanghai Journal of Acupuncture and Moxibustion 2017;36(6):735-738
Objective To investigate the clinical efficacy of shoulder-three-points warm needling moxibustion plus conventional rehabilitation in recovery from arthroscopic rotator cuff repair.Method Seventy patients who had undergone arthroscopic rotator cuff repair for rotator cuff injury were enrolled and randomly allocated to groups A and B, 35 cases each. Group A received conventional rehabilitation and group B, shoulder-three-points warm needling moxibustion in addition. Functional activity and pain in the affected shoulder were scored using the American Shoulder Elbow Scale (ASES), the University of California at Los Angeles (UCLA) Shoulder Scale and the Constant-Murley Shoulder Outcome Score in the two groups before and after treatment.Result There were statistically significant pre-/post-treatment differences in the ASES, UCLA and Constant-Murley scores in the two groups (P<0.01). After treatment, the scores were higher in group B than in group A, but there was no significant difference in the UCLA function subscore (P>0.05) and a significant difference in the UCLA pain subscore (P<0.01) between groups A and B. Conclusion shoulder-three-points warm needling moxibustion plus conventional rehabilitation training can markedly promote postoperative rehabilitation and especially relieve postoperative pain in patients with rotator cuff injury. It provides a new idea for clinical shoulder rehabilitation in the future.
2.A comparative study of the bony fusion in different degrees of vertebral plate hinge fracture after single open-door cervical expansive laminoplasty with centerpiece mini-plate fixation
Shengjun ZHANG ; Xin XU ; Zhi HUANG
Chinese Journal of Postgraduates of Medicine 2014;37(20):22-25
Objective To compare the bony fusion in different degrees of vertebral plate hinge fracture after single open-door cervical expansive laminoplasty with centerpiece mini-plate fixation.Methods The clinical data of 79 patients received the unilateral simple open-door cervical expansive laminoplasty with centerpiece mini-plate fixation from January 2010 to December 2012 were retrospectively analyzed.The vertebral plate hinge fracture was divided into incomplete fracture and complete fracture according to thepostoperative CT scan.The complete fracture was divided into four types:type Ⅰ in which there was no displacement;type Ⅱ in which there was mild to moderate displacement;type Ⅲ in which there was complete displacement or separated; type Ⅳ in which there was hinge' s collapse into cervical canal.The hinge fracture healing was observed and the difference of different types of fracture healing rate was compared.Results Follow-up of 12-45 (21.2 ± 5.6) months.CT scan found 395 segments 1 week after the operation,vertebral plate hinge complete fracture accounted for 58.2% (230/395).And type Ⅰ accounted for 66.1% (152/230),type Ⅱ accounted for 25.7%(59/230),type Ⅲ accounted for 6.5%(15/230) and type Ⅳ accounted for 1.7% (4/230).The fusion rate of incomplete fracture at 6 months after the operation was higher than that complete fracture [97.6%(161/165) vs.80.9%(186/230)],there was significant difference (P< 0.05).The fracture rate in different types of complete fracture at 3,6 months after the operation had significant difference (P < 0.05).Type Ⅲ fracture had the lowest healing rate.Conclusion Type Ⅰ fracture is the major type for vertebral plate hinge complete fracture,complete fracture get a relatively bad bony fusion and type Ⅲ fracture has the lowest healing rate.
3.Prognostic factors for long-term survival of clinical resectable intrahepatic cholangiocarcinoma
Lifeng MA ; Shengjun XU ; Jianfeng CHEN ; Yuan XU
Chinese Journal of Primary Medicine and Pharmacy 2015;(11):1616-1619,1620
Objective To assess these in a consecutive series of patients with ICC treated surgically. Methods A retrospective study was conducted on 189 ICC patients undergoing surgery.Surgical results and survival were evaluated and compared among different subgroups of patients.Univariate and multivariate analyses were performed to identify prognostic factors.Results R0,R1,R2 resection and exploratory laparotomy were obtained in 63,84,31 and 11 patients,respectively.The overall 5 -year survival rates for the entire cohort were 16.8%,with corresponding rates of 26.3% for patients with R0 resection;14.3% for patients with R1 resection;6.8% for patients with R2 resection;and 0.0% for patients with an exploratory laparotomy.Independent factors for poor survival included positive resection margin,multiple tumors,beta - catenin nuclear expression and lymph node metastasis. Conclusion R0 resection offers the best possibility of long -term survival,but the chance of a R0 resection is low when surgery is performed for potential resectable ICC.Patients with characteristics of beta -catenin nuclear expres-sion,multiple tumors and lymph node metastasis are indicated to surgery which is needed to be further studied.
4.Expression of CD44v6 in Gastric Carcinoma and Its Clinical Significance
Shengjun XU ; Bingkui HU ; Zhiqiang LING ; Ting ZHAO
Chinese Journal of Bases and Clinics in General Surgery 2004;0(01):-
Objective To study the relationship between expression of CD44v6 in gastric carcinoma and neoplasm metastasis and prognosis. Methods Expression of CD44v6 in 52 cases of gastric carcinoma was assayed by flow immunocytometry, and its relation with clinical pathology and prognosis was analyzed. Results In 52 cases of gastric carcinoma tissue, the positive rate of CD44v6 expression was 67.31%(35/52); but the positive rate of CD44v6 expression in normal gastric tissue was 25.00% (13/52). The positive rate of expression was significantly different (P
5.Practice and experience in research capacity building in a miliary teaching hospital
Shengjun WANG ; Zhengmei XU ; Jiang PU ; Lijuan LIU ; Qiang GUO
Chinese Journal of Medical Science Research Management 2015;28(2):188-190
This paper discusses the issues related to research capacity building in a military teaching hospital.We analyzed the opportunities,challenges and proposed development of military hospitals in order to strengthen the collaboration,,to adjust disciplinary structure,to consolidate research platform,to promote international exchanges,and to train the talented researchers and eventually to improve the hospital's overall research capacity.
6.External Application of Chinese Medicine following Tapping Using a Plum-blossom Needle for Allergic Rhinitis
Xiuhui YANG ; Shengjun XU ; Jingjing WEI ; Chouping HAN
Journal of Acupuncture and Tuina Science 2010;8(2):98-101
Objective:To observe the clinical efficacy of extemal application of Chinese medicine following tapping using a plum-blossom needle for allergic rhinitis.Methods:All 328 cases were randomized into an observation group of 206 cases,Chinese medicine group of 70 cases and point application group of 52 cases.Results:The differences between the observation and Chinese medicine groups (P<0.01) and between the observation and point application group (P<0.05) were both of statistical meaning.The cases in the observation obtained the best effect,the point application group obtained a moderate effect and the Chinese medicine group obtained the least effect.A younger age and an increased number of treatments contributed to a better effect.Conclusion:External application of Chinese medicine following tapping using a plum-blossom needle is safe and effective for allergic rhinitis.
7.Identification of Physalis Angulatae Fructus Seu Calyx and its Adulterant Physalis Calyx Seu Fructus
Xuefeng ZHANG ; Yuexin XU ; Saiwen DONG ; Shengjun HU
China Pharmacist 2015;(8):1394-1397
To establish the identification method for Physalis angulatae fructus Seu calyx and Physalis calyx Seu fruc-tus. Methods:Four methods including macroscopy,microscopy,TLC and HPLC were used. Results: There were some differences in macroscopic and microscopic characteristics and physicochemical identification between Physalis angulatae Fructus Seu Calyx and Phys-alis Calyx Seu Fructus. Conclusion:The established method is simple and easy,which can objectively and accurately distinguish Phys-alis angulatae Fructus Seu Calyx from Physalis Calyx Seu Fructus.
8.The significance of peripheral blood CD4 + T cell-derived leptin in asthmatic children
Qinglei XU ; Baolin ZHU ; Xiaobo MA ; Wei ZHANG ; Lingling LIU ; Shengjun WANG ; Jianguo CHEN
Journal of Clinical Pediatrics 2014;(2):122-125
Objectives To explore the role of CD4+T cell-derived leptin in peripheral blood mononuclear cells (PBMC) in asthmatic children. Methods Peripheral blood mononuclear cells were isolated from peripheral blood of both healthy subjects and asthmatic children in attack and remission stages. CD4+T cells were purified from PBMCs by mag-netic beads and were cultured in vitro. Supernatants were used to detect the levels of leptin by ELISA. The expression of the orphan nuclear receptor (ROR)γt was detected by real-time quantitative PCR (qRT-PCR) method. Results There was significant difference in CD4+T cell-derived leptin levels of asthmatic children in attack stage (68.46±13.08 pg/ml), remis-sion stage (36.73±6.13 pg/ml) and normal controls (32.82±5.79 pg/ml) (P<0.01). Through pairwise comparison, the leptin levels in children in attack stage were significantly higher than those in remission stage and normal control groups (P<0.01). But no statistical significance was found between remission stage group and normal controls (P>0.05). The plasma leptin of children in attack stage and remission stage, as well as in normal subjects were 16.64 ± 3.53, 14.91 ± 3.24 and 13.72 ± 5.79 ng/ml respectively with no significant differences (P>0.05). The levels of RORγt mRNA were 0.341 ± 0.175, 0.089±0.028 and 0.068±0.018 in children with asthma during attack stage, remission stage and in normal children respec-tively (P<0.01). Compared to remission and normal control groups, the RORγt mRNA level of children in attack stage was markedly higher (P<0.01), but there was no significant difference between asthmatic children in remission stage and the healthy controls (P>0.05). Furthermore, the result of this study showed CD4+T cell-derived leptin positively correlated to RORγt in asthmatic children in attack stage (r=0.681, P<0.01). Conclusions CD4+T cell-derived leptin is elevated in asthmatic children in attack stage and its level is closely related to the pathological process of asthma.
9.Relationship between distribution of infected snails and transmission of acute schistosomiasis in hilly regions
Yixiang XU ; Chengzhong CHU ; Yunlong WU ; Shengjun CHENG ; Fenghua GAO ; Gonghua ZHANG ; Jin CHENG ; Siwu WANG
Chinese Journal of Schistosomiasis Control 2010;22(1):72-73
Objective To explore the relationship between the distribution of infected snails and transmission of acute schistosomiasis in hilly regions.Methods The data concerning the distribution of the infected snails and acute schistosomiasis in Shitai County,Anhui Province from 1999 to 2008 were collected and analyzed.Results The sehistosome infection rate of human increased as the distance between the settings with infected snails and activity sites of humans shortened.Conclusions Acute infection of schistosome of human is associated with the distance between the settings with infected snails and activity sites of them.Strengthening the measures of snail control in key regions,protecting key populations and carrying out health education for schistosomiasis control are important approaches to control the transmission of acute schistosomiasis in hilly regions.
10.Detection and clinical significance of peripheral blood CD 4+T cell-derived leptin in patients with Hashimoto′s thyroiditis
Qinglei XU ; Baolin ZHU ; Xiaobo MA ; Wei ZHANG ; Lingling LIU ; Shengjun WANG ; Jianguo CHEN
International Journal of Laboratory Medicine 2014;(5):531-532
Objective To detect the level of CD4+ T cell-derived leptin(LP) in peripheral blood mononuclear cells(PBMC) from the patients with Hashimoto′s thyroiditis(HT) and to investigate its role in the occurrence and development of HT .Methods The peripheral blood samples in the patients with HT and the healthy controls were collected and separated for obtaining PBMC .The CD4+ T cells magnetic beads was adopted to separate CD4+ T cells for culturing in vitro .The LP level in supernatant was detected by ELISA .The relative expression amount of the orphan nuclear receptor RORγt was detected by real-time quantitative PCR (qRT-PCR) method .Results The LP level of CD4+ T cell culture liquid in the HT patients was markedly higher than that in the healthy control group ,difference was statistically significant (P<0 .05) .Furthermore ,the LP level in CD4+ T cell culture liquid was posi-tively related with the relative expression amount of RORγt in HT patients .Conclusion The CD4+ T cell-induced leptin level is in-creased in HT patients ,which is closely related with the occurrence and development of HT .