1.Effect of hemorheology on ultrasonic doppler blood flow spectrum diagram.
Journal of Biomedical Engineering 2014;31(4):798-800
The present research aims to point out the long-existing defect of analyzing the spectrum diagram only from the perspective of haemodynamics instead of haemorheology. In the light of the theories of haemodynamics and haemorheology, the causes of spectrum diagram formation of carotid artery blood at the rapid and slow flow can be clarified completely and accurately. Four conclusions have been drawn in the end. As long as the velocity gradient is large enough, obvious red blood cells concentrate to the shaft even in the big or bigger blood vessels; the spectrum diagram is the powerful proof of the two phase flow model of blood; the spectrum diagram can be completely and accurately analyzed only by combining haemodynamics with haemorheology; and only when the red blood cells concentrate to the shaft, the big or bigger blood vessels can be regarded as haemogeneous fluid.
Blood Flow Velocity
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Carotid Arteries
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diagnostic imaging
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Hemodynamics
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Hemorheology
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Humans
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Ultrasonography, Doppler
2.Summing up Experiences and Pushing the Development of Clinical Hemorheologic of my Nation in Depth
Chinese Journal of Medical Physics 2010;27(2):1821-1824
Objective: Pushing the development of scientific research, education and clinical applying of hemorheologic in eath part comprehensively and in depth. Methods: Summarizing the experiences, lessons and questions in scientific research, edu-cation and clinical applying of hemorheologic in twenty and more years, clarifying the harm of high viscosity to health. Re-sults: Stating the foundation, necessity and feasibility of the overall and deep development have been possessed. Conclusions: Hemorheologic can be developed comprehensively and in depth provided that studying good experiences, cultivating talent, playing the role of learning organizations and conquering the existing questions.
3.EFFECT OF LYCIUM BARBARUM POLYSACCHARIDE ON ANTITUMOR ACTIVITY AND IMMUNE FUNCTION
Lu GAN ; Shenghua ZHANG ;
Acta Nutrimenta Sinica 1956;0(02):-
Objective: To study the antitumor effect of Lycium barbarum polysaccharide (LBP X) and its immunity regulating effect on S 180 bearing mice. Methods: S 180 bearing mice were used as animal model. The effect of LBP X on tumor weight and immune function was observed. Results: LBP X could inhibit the growth of S 180 effectively and increase thymus index, the macrophage phagocytic function, anti SRBC antibody secreted by the spleen cells, lymphocyte proliferation and CTL activity and decrease LPO markedly in S 180 bearing mice. Conclusion: The mechanism of tumor inhibition by LBP X was due to enhance the immune function.
5.U-100 laser lithotripsy through extra-thin choledochoscope under mini-incision for refractory choledocholithiasis
Chenggang ZHANG ; Shenghua ZHANG ; Shouquan FENG
Chinese Journal of Current Advances in General Surgery 1999;0(03):-
Objective:To explore the value of applying the U-100 laser lithotripsy through extra-thin choledochoscope under miniincision to treat the refractory common bile duct stones.Methods:The curative effect and complications of 68 patients were observed.Results:All of the operations were succeeded whithout cases of death.67 cases’ biliary stones were completely removed,and the stone free rate is 98.52%,only 4 cases have complications.Transcystic bile duct exploration were performed in 29 patients,and CBDE were performed in 39 patients,the average postoperative time of in hospital stay is only 10.5 days.Conclusion:The treatment plan has the advantages of mini invasion,high efficiency and low postoperative complication rate,so it’s safe and practicable.
7.Studies on structural characteristics of protein-bond polysaccharide Le-3 from fruitbody of Lentinus edodos
Juan YANG ; Moucheng WU ; Shenghua ZHANG ;
Chinese Traditional and Herbal Drugs 1994;0(09):-
Object To study the structural characteristics of protein bond polysaccharide Le 3 from the fruitbody of Lentinus edodos (Berk ) Pegler Methods Relative molecular weights were determined by gel permeation chromatography Structural characteristics were expounded by infra red scan, gas chromatography, ? elimination reaction and Sepharose gel electrophoresis The content of total polysaccharide and protein were determined by colorimetry Results Mean molecular weight and molecular number of Le 3 were 13 700 and 12 500 Typical absorption peak of the polysaccharide as shown in infra red spectrum was of ? type glycosidic linkage Le 3 was composed of arabinose, xylose, mannose, galactose, glucose and glucuronic acid The molar ratio of the neutral saccharides was Ara∶Xyl∶Man∶Gal∶Glu=0 31∶0 47∶1 00∶1 15∶8 92 The content of total saccharide and protein were 70 62% and 25 31% The saccharides were not linked to peptides chain through O glycosidic linkage Le 3 contained RNA Conclusion Le 3 was a kind of new type polysaccharide isolated from the fruitbody of L edodes
8.Hypoglycemic Effects of Yifusheng on Experimental Animals with Hyperglycemia
Shenghua LU ; Hua ZHANG ; Jianfen MA
Traditional Chinese Drug Research & Clinical Pharmacology 2000;0(05):-
Hypoglycemic effects of Yifusheng on hyperglycemia animals induced by alloxan or adrenaline were studied.The result showed that Yifusheng in the dosage of 0.25 g/kg and 0.125 g/kg could significantly decrease the content of plasma blood sugar(P
9.EFFECT OF SOYASAPONINS IN PREVENTION OF HYPERLIPIDEMIA IN MICE AND ITS MOLECULAR MECHANISM
Junxia XIAO ; Guanghua PENG ; Shenghua ZHANG
Acta Nutrimenta Sinica 1956;0(02):-
Objective: To investigate effect of soyasaponins in the prevention of hyperlipidemia in mice and its molecular mechanism. Methods: 56 healthy mice were randomly divided into 7 groups according to their levels of TC in serum: normal control, high fat control, high fat with 20mg/kg.d gypenosides,high fat with soyasaponins of four doses(5 mg/kg.d, 10mg/kg.d, 20mg/kg.d, 30 mg/kg.d). Results: As compared to high fat control soyasaponins significantly reduced the serum TC, LDL-C, TG concentrations, and increased the HDL-C levels distinctly. They significantly deceased MDA content, increased the activities of SOD and LPL in liver. The results of RT-PCR showed that high fat feeding could induce the reduction of LPL mRNA expression, while soyasaponins could increase it. Conclusion: Soyasoponins prevent hyperlipidemia through upregulation of LPL mRNA expression and increase of antioxidative capacity.
10.Studies on distribution and accumulative dynamic variation of bioactive components in Eucommia ulmoides
Xiangyang QI ; Weijun CHEN ; Shenghua ZHANG ;
Chinese Traditional and Herbal Drugs 1994;0(12):-
Object To study the effects of districts, seasonal variations and treatments in past harvest on the five main bioactive components in the barks and leaves of Eucommia ulmoides Oliv Methods The contents of them in the bark and leaves of E ulmoides were determined by RP HPLC Results The contents of (+) pinoresinol di O ? D glucopyranoside (PG), (+) syringaresinol di O ? D glucopyranoside (SG), chorgenic acid (CGA), geniposide (GP), geniposidic acid (GA) among the sample of E ulmoides from different growing districts were obvious difference Besides, the amount of different bioactive components in the same sample had no correlation Seasonal variation and different past harvest treatments had great influence on the bioactive component in E ulmoide. Based on the monthly variation of their main bioactive component, the suitable seasons for harvest of the barks and leaves of E ulmoides are April, May and July respectively, and intracellular enzymes in the fresh barks and leaves collected should be inactivated imediately before drying to avoid lossing the bioactive components In addition, between the barks and leaves of E ulmoides, the major bioactive component had great differences, but had complementarity Conclusion The districts, seasonal variatons and past harvest treatments have great effects on the contents of five main bioactive components in the barks and leaves of E ulmooides, and the barks couldn't be replaced by the leaves simply