Aim To discover the change of synaptic plasticity by supplementing DHA during development period in rats. Method We divided Wistar rats into two groups: fish oil group and control group. The fish oil rats were supplemented with fish oil(5?10~3 ml?g-1 body weight) by gavage daily. The control rat was supplemented with NS of the same dose. 90 days later, each rat was hippocampus of anaesthetized and LTP and LTD were recorded at hippocampus of the same rat. Result Compared to the control group, DHA group presented an obvious increase in PS LTP, while no changes were found in EPSP LTP. On the other hand,DHA group demonstrated an obvious canceling effect on both EPSP and PS LTD. Conclusion There exist effects on synaptic plasticity after supplement with DHA. It may be one of the factors that DHA improves learning and memory.

AIM: To observe the short-term curative effect of Suxiao Jiuxin Pill on coronary heart disease (CHD) and angina pectoris. METHODS: 187 patients were divided into two groups at random:the treatment group with 105 cases and the control group with 82 cases. The treatment group was given Suxiao Jiuxin Pill 6 pills tid and the control group was given Compound Danshen Dripping Pill 6 pills tid orally. The treating period was 2 weeks. Before and after treatment angina pectoris was observed and electrocardiogram was determined. RESULTS: Suxiao Jiuxin Pill could significantly alleviate syndrome of CHD in patients, lessen electrocardiogram and decrease dosage of nitroglycerin. The total effective rate on angina pectoris and the effective rate in improving electrocardiogram was higher in treatment group than that in control group (P