China ; epidemiology ; Communicable Disease Control ; Humans ; Severe Acute Respiratory Syndrome ; epidemiology ; prevention & control

Accident Prevention ; China ; Humans ; Wounds and Injuries ; prevention & control

Child ; Child Abuse ; legislation & jurisprudence ; prevention & control ; China ; Delivery of Health Care ; organization & administration ; Domestic Violence ; legislation & jurisprudence ; prevention & control ; Female ; Human Rights Abuses ; legislation & jurisprudence ; prevention & control ; Humans ; Violence ; legislation & jurisprudence ; prevention & control ; World Health Organization ; organization & administration

Accidents, Traffic ; mortality ; prevention & control ; China ; epidemiology ; Global Health ; Humans ; Wounds and Injuries ; epidemiology

China ; Disasters ; Earthquakes ; Emergency Medical Services ; manpower ; organization & administration ; Humans ; Public Health Practice

Accident Prevention ; Humans ; Public Health ; Terminology as Topic ; Wounds and Injuries ; classification

Objective To review the study on the risk factors and prognosis of laparoscopic cholecystectomy remedied by laparotomy. Methods Five hundred cases of laparoscopic cholecystectomy patients in our hospital were collected as a research object ,using univariate analysis and multivariate logistic regression analysis to screen and analyze laparotomy during laparoscopic cholecystectomy ,and its prognosis. Results 500 cases of cholecys-tectomy patients were converted to laparotomy in a ratio of 4.2%. The independent risk factors contained BMI index,patients with history of abdominal surgery,patients with cholecystitis episodes,doctors clinical experience , patients with gallbladder wall thickness during laparoscopic cholecystectomy. Twenty-one patients undergone laparotomy during laparoscopic cholecystectomy without severe complications. Conclusion Before laparoscopic cholecystectomy,physicians should analyze the following factors comprehensively in obesity,abdominal surgery, recurrent cholecystitis,gallbladder wall thickness,in order to determine the operating method and reduce the the rate from laparoscopic cholecystectomy to laparotomy.

Objective To study the subchronic toxicity of sodium fluoride on mRNA expression of estrogen receptor(ER) in female mice.Methods Forty female mice were randomly divided into 4 groups according to body mass,10 in each group,and exposed to sodium fluoride solution(0,1,5,25 mg/L) through drinking water in control,low-dose,medium-dose and high-dose groups for 12 weeks.The expression levels of ERα,ER3 mRNA in ovarian tissues were determined by RT-PCR method.Results The relative expression levels of ERα,ERβ mRNA in control,low-,medium-and high-dose groups were 0.7028 + 0.0474,0.7195 ± 0.0552,0.6479 ± 0.0590,0.5684 ± 0.0513 and 0.8418 ± 0.0131,0.7729 ± 0.0974,0.7610 ± 0.0984,0.8026 ± 0.0234,respectively.The difference between high-dose and control groups of the expression level of ERα was statistically significant (P ＜ 0.05).Conclusions The subchronic toxicity of fluoride can decrease the expression of estrogen receptor in ovarian tissue,which may have a certain effect on reproductive development of female mice.

China ; Data Collection ; Safety ; Wounds and Injuries ; prevention & control

Breast ; radiation effects ; Breast Neoplasms ; pathology ; radiotherapy ; surgery ; Female ; Humans ; Lymphatic Metastasis ; Mastectomy ; Mastectomy, Segmental