1.Analysis of the Puzzle between Acupuncture Community and Acupuncture Clinical Trials.
Chinese Journal of Integrated Traditional and Western Medicine 2016;36(3):261-265
Recently a number of acupuncture clinical trial projects mainly conducted by conventional scientists have generated many negative results. A large meta-analysis of patient-level acupuncture data for the treatment of chronic pain conditions have demonstrated that the effects of verum acupuncture on pain improvement have statistically significant, but small, differences compared with sham-acupuncture procedures and no difference between acupuncture points and non-points. These conclusions have puzzled the acupuncture community and made confusion for acupuncture research and practices. The purpose of this paper was to compare differences between acupuncture clinical practices and the trial studies, which include "acupuncture technical principles", "acupuncture clinical trial design", and "acupuncture practice based on the theory of traditional Chinese medicine". These factors contribute to the puzzle between the acupuncture community/practice and acupuncture clinical trials, which can be improved in future studies.
Acupuncture Points
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Acupuncture Therapy
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Chronic Disease
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Clinical Trials as Topic
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Humans
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Meta-Analysis as Topic
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Pain Management
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methods
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Research Design
2.Effect of Acupuncture on Prognosis and Immune Function of Sepsis Patients.
Qiu-sheng XIAO ; Ming-yuan MA ; Xing-sheng ZHANG ; Meng-hua DENG ; Zhul Yang YAN
Chinese Journal of Integrated Traditional and Western Medicine 2015;35(7):783-786
OBJECTIVETo study the effect of acupuncture on the immune function of sepsis patients.
METHODSNinety sepsis patients were assigned to the control group, the thymosin a1 group, and the acupuncture treatment group according to random digit table, 30 patients in each group. Patients in the control group were treated according to the guideline of Surviving Sepsis Campaign (SSC). Patients in the control group received routine treatment. Those in the thymosin alpha1 group additionally received subdermal injection of thymosin alpha1 (1.6 mg), once per day for 6 successive days. Needling at related points such as Zusanli (ST36), Yanglingquan (GB34), Neiguan (PC6), Guanyuan (RN4), and so on, was performed in patients of the acupuncture treatment group, once per day for 6 successive days. T cell subgroups (CD3+, CD4+, CD8+, CD4+ /CD8+) and immunoglobulin levels (IgG, IgA, IgM) were detected. The length of ICU hospital stay, hospital readmission rate, and 28-day mortality were compared among the three groups.
RESULTSAfter six days of treatment, CD3+, CD4+, CD8+, IgG, IgA, IgM, and CD4+ /CD8+ ratio of three groups were all significantly increased (P < 0.01). Of them, CD3+, CD4+, CD8+, IgG, IgA, and IgM increased more significantly in the thymosin alpha1 group and the acupuncture treatment group (P < 0.01). Compared with the control group, the ICU hospitalization length was significantly shortened, the hospital readmission rate and the 28-day mortality were lower in the thymosin alpha1 group and the acupuncture treatment group (P < 0.05, P < 0.01). There was no statistical difference in each index between the thymosin alpha1 group and the acupuncture treatment group (P > 0.05).
CONCLUSIONAcupuncture could adjust the immune function of sepsis patients, improve their immunological indicators and prognoses.
Acupuncture Therapy ; CD4-CD8 Ratio ; Humans ; Length of Stay ; Prognosis ; Sepsis ; diagnosis ; immunology ; therapy ; T-Lymphocyte Subsets ; Thymosin ; analogs & derivatives
3.Ancient clinical application of massage therapy on navel.
Xing-Yue YANG ; Yu-Xiao MA ; Si-Sheng TIAN ; Shu-Zhong GAO
Chinese Acupuncture & Moxibustion 2014;34(7):719-720
To further explore the clinical effect of massage therapy on navel,the related ancient literatures were arranged and analyzed,and several methods in ancient clinical were introduced, including stroking navel, rubbing navel, pushing navel, tapping navel and puffing navel. In addition, the theoretical basis of massage therapy on navel were discussed. The results revealed ancient literatures offered abundant theoretical basis to modern clinical practice, and there were evidences of treating gastroenteric and gynecological diseases with this therapy. Comprehensively, through the study of ancient literatures and modern research, therapy of massage on navel is believed to be promising and will gain popularity in the future.
China
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History, Ancient
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Humans
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Massage
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history
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Medicine in Literature
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Umbilicus
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physiopathology
4.Preliminary study of clinical significance of decreased D(L)CO in patients with left ventricular heart failure.
Xiao-yue TAN ; Xing-guo SUN ; Sheng-shou HU ; Jian ZHANG ; Jie HUANG ; Zhi-gao CHEN ; Li MA
Chinese Journal of Applied Physiology 2015;31(4):357-360
OBJECTIVEThis study aimed to investigate the feature of D(L)CO (Diffusion Lung Capacity for Carbon Monoxide) in CHF (left ventricular heart failure) patients, underlying pathophysiological mechanism and clinical significance.
METHODSWe retrospectively studied the D(L)CO, pulmonary ventilation function, cardiopulmonary exercise testing and related clinical information in severer HF patients.
RESULTSPeak VO2 severely decreased to 34 ± 7 percentage of predicted(%pred) and anaerobic threshold to 48 ± 11%pred in all patients. D(L)CO moderately decreased to 63 ± 12%pred and there were 25 patients lower than 80%pred. FVC, FEV1, FEV1/FVC and TLC were 75 ± 14%pred, 71 ± 17%pred, 97 ± 11%pred, and 79 ± 13%pred, which indicated borderline or mild restrictive ventilatory dysfunction. The decrease of D(L)CO was more severe than those of TLC, FEV1 and FVC.
CONCLUSIONFor patients with severe CHF, cardiopulmonary exercise function is extremely limited, D(L)CO generally moderately declines and ventilation function is merely mildly limited. D(L)CO is the parameter for cardiopulmonary coupling, reflecting limitation of the cardiovascular dysfunction while without ventilatory limit.
Blood Gas Analysis ; Heart Failure ; physiopathology ; Humans ; Respiratory Function Tests ; Retrospective Studies ; Ventricular Dysfunction, Left ; physiopathology
5.Central Blood Pressure and the Extent of Coronary Artery Disease
Yuan-Yuan DUAN ; Hui-Liang LIU ; Dong-Xing MA ; Sheng-Li YANG ; Jian-Ping LUO ; Ying LIU ; Wei HAN ;
Chinese Journal of Hypertension 2006;0(10):-
50%.The patients were categorized into as:one-,two-, and three-vessels coronary artery disease group.Central aortic SBP and DBP was measured by cathetarization dur- ing angiography of coronary artery and brachial blood pressure was measured using cuff method.Results Periph- eral SBP,PP and ascending aortic SBP,PP,fractional systolic pressure(FSP=SBP/MAP)were increased and as cending aortic fractional diastolic pressure(FDP=DBP/MAP)was reduced when the diseased coronary vessels were increased(P
6.Chemical constituents from Ganoderma philippii.
Shuang YANG ; Qing-Yun MA ; Sheng-Zhuo HUANG ; Hao-Fu DAI ; Zhi-Kai GUO ; Zhi-Fang YU ; You-Xing ZHAO
China Journal of Chinese Materia Medica 2014;39(6):1034-1039
The chemical investigation on Ganoderma philippii led to the isolation of sixteen compounds by silica gel and Sephadex LH-20 column chromatography. On the basis of spectroscopic data analyses, their structures were elucidated as 2, 5-dihydroxyacetophenone (1), methyl gentisate (2), (S) -dimethyl malate (3), muurola-4, 10 (14) -dien-11beta-ol (4), dihydroepicubenol (5), 5-hydroxymethylfuran carboxaldehyde (6), ergosta-7, 22E-dien-3beta-ol (7), ergosta-7, 22E-dien-3-one (8), ergosta-7, 22E-diene-2beta, 3alpha, 9alpha-triol (9), 6/beta-methoxyergo-sta-7, 22E-dien-3beta, 5alpha-diol (10), ergosta-4, 6, 8(14), 22E-tetraen-3-one (11), ergosta4, 6, 8-(14), 22E-etetraen-3beta-ol (12), 5alpha, 8alpha-epidioxy-ergosta-6, 22E-dien-3beta-ol (13), 7alpha-methoxy-5alpha, 6alpha-epoxyergosta-8-(14), 22E-dien-3beta-ol (14), ergosta-8, 22E-diene-3beta, 5alpha, 6beta, 7alpha-tetraol (15), and ergosta-5, 23-dien-3beta-ol, acetate (16). All the compounds were obtained from this fungus for the first time, and compounds 4 and 5 were isolated from the Ganoderma genus for the first time.
Ganoderma
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chemistry
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Medicine, Chinese Traditional
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Organic Chemicals
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analysis
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isolation & purification
7.Effect of the rolB gene on phenotypic development and tropane alkaloids biosynthesis in Atropa belladonna
Wen-wen AO ; Ai-juan TAN ; Bing-nan MA ; De-hui MU ; Xing-xing LU ; Hang PAN ; Ming-sheng ZHANG ; Wei QIANG
Acta Pharmaceutica Sinica 2023;57(6):1705-1712
The
8.Forensic application of brainstem auditory evoked potential in patients with brain concussion.
Xing-Bin ZHENG ; Sheng-Yan LI ; Si-Xing HUANG ; Ke-Xin MA
Journal of Forensic Medicine 2008;24(6):433-441
OBJECTIVE:
To investigate changes of brainstem auditory evoked potential (BAEP) in patients with brain concussion.
METHODS:
Nineteen patients with brain concussion were studied with BAEP examination. The data was compared to the healthy persons reported in literatures.
RESULTS:
The abnormal rate of BAEP for patients with brain concussion was 89.5%. There was a statistically significant difference between the abnormal rate of patients and that of healthy persons (P<0.05). The abnormal rate of BAEP in the brainstem pathway for patients with brain concussion was 73.7%, indicating dysfunction of the brainstem in those patients.
CONCLUSION
BAEP might be helpful in forensic diagnosis of brain concussion.
Accidents, Traffic
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Adolescent
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Adult
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Brain Concussion/physiopathology*
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Child
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Evoked Potentials, Auditory, Brain Stem
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Female
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Forensic Medicine
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Humans
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Male
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Middle Aged
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Young Adult
9.Effect of maxillary protraction with or without rapid palatal expansion in treating early skeletal Class III malocclusion.
Wen-sheng MA ; Hai-yan LU ; Fu-sheng DONG ; Xiao-ying HU ; Xing-chao LI
West China Journal of Stomatology 2009;27(2):178-182
OBJECTIVETo evaluate the effectiveness of treatment with maxillary protraction with or without rapid palatal expansion (RPE) for skeletal Class III malocclusion in mixed dentition.
METHODSA total of 31 children with Class III malocclusion in mixed dentition were selected, and 15 (group A) received maxillary protraction treatment with RPE, the other 16 (group B) received maxillary protraction without RPE. Cephalometric films were taken before and after treatment, and traditional and Pancherz analysis were used.
RESULTSThe average duration of treatment was 10.14 months in group A and 9.77 months in group B respectively (P>0.05). According to Pancherz analysis, maxillary basal bone moved forwards by 2.99 mm in group A and 3.33 mm in group B respectively (P>0.05), mandibular basal bone moved backwards by 0.07 mm in group A, while forwards by 0.80 mm in group B (P>0.05), the overjet increased by 4.51 mm in group A and 6.37 mm in group B respectively (P<0.05), and the molar relationship improved by 4.97 mm in group A and 4.73 mm in group B respectively (P>0.05). The effects were clinically satisfactory in the both groups. Lower molar moved forwards by 1.18 mm in basal bone in group A, while backwards by 1.20 mm in group B (P<0.05). Traditional cephalometric analysis showed no statistic differences between the two groups except that upper incisior showed greater procline in group B than in group A (P<0.05).
CONCLUSIONThe study shows that maxillary protraction treatment, with or without RPE, is clinically satisfactory to correct early skeletal Class III malocclusion.
Cephalometry ; Child ; Extraoral Traction Appliances ; Female ; Humans ; Male ; Malocclusion, Angle Class III ; Mandible ; Maxilla ; Molar ; Palatal Expansion Technique
10.Image integration system to guide catheter ablation of atrial tachycardia with a multi-key-isthmus reentrant in a patient with a repaired atrial septal defect: a case report.
Rong-hui YU ; Jian-zeng DONG ; Xing-peng LIU ; De-yong LONG ; Jun-ping KANG ; Chang-sheng MA
Chinese Medical Journal 2008;121(9):859-861