1.Investigation of the Effect of Preparing Lessons Collectively in Teaching Endocrinology
Chinese Journal of Medical Education Research 2003;0(02):-
In order to improve the effect of teaching and teachers' ability,make our teaching methods adapt to the social development,the department of Endocrinology used the method of preparing lessons collectively in our teaching.We found that the method not only made the the supply of teachers reasonably but also made good contribution to the students' culture.Practice testified that the method of preparing lessons collectively could adapt to the new model of cultivation and create substantial results.
2.Effects ofTanyu Tongzhi Formula Drug-Containing Serum on Proliferation and Migration of Human Umbilical Vein Endothelial Cells
Chinese Journal of Information on Traditional Chinese Medicine 2015;(1):50-52
Objective To observe the effects ofTanyu Tongzhi Formula on proliferation and migration of human umbilical vein endothelial cells (HUVECs);To explore its activity of pro-angiogenesis.Methods HUVECs were cultured in vitro. Rats were treated with gavage containing different doses ofTanyu Tongzhi Formula (78.0, 39.0, 19.5 g/kg) to prepare serum with different doses of medicine. The activity of HUVECs was measured by MTT method. The effects on migration of HUVECs were inspected by using scratch wound assay.Results Compared with the normal control group, serum containing high-dose and medium-doseTanyu Tongzhi Formula could significantly promote the proliferation of the HUVECs (P<0.01). The rates were 49.78% and 33.92% respectively. And the cell migration rate was higher in the two groups than in the normal control group (P<0.01). The rates were 11.36% and 11.62% respectively.ConclusionTanyu Tongzhi Formula can promote proliferation and migration in HUVEC, which may be active to pro-angiogenesis.
3.Research progress of vitamin D overdoes or toxicosis.
Chinese Journal of Pediatrics 2015;53(3):235-237
4.Correlation between histochemical location and content of artemisinin
Chinese Traditional and Herbal Drugs 1994;0(09):-
Object To determine the histochemical location d eposited artemisinin and to provide selection character for screening of Artemisia annua L. which contains rich content of artemisinin Methods Artemisinin was located by the histochemic al method and then statistical method was used to ascertain the correlation betw een the content of artemisinin and the density of biseriate glandular triche mes (BGT) Results Artemisinin is located in both BGT and non glandular T -shaped filamentous trichomes (NTFT) in A annua leave s The content of artemisinin had a positive correlation with the density of BG T in A annua leaves Conclusion High density of BGT in foliar tissue might be considered as one of the selection characters for the screening of A. annua with rich content of artemisinin
5.Changes in sagittal balance following corrective osteotomy for lumbar degenerative kyphosis
Zhouliang REN ; Songqing ZHU ; Weidong LIANG ; Weibin SHENG ; Jun SHENG
Chinese Journal of Tissue Engineering Research 2016;20(4):564-570
BACKGROUND: At present, more and more scholars pay attention to the influence of spine and pelvis sagittal balance on the quality of life of patients. Postoperative changes in spine imaging parameters fol owing corrective osteotomy for lumbar degenerative kyphosis have not been reported. OBJECTIVE: To evaluate postoperative changes in sagittal balance fol owing corrective osteotomy for lumbar degenerative kyphosis. METHODS: We retrospectively analyzed 35 consecutive lumbar degenerative kyphosis patients treated with posterior osteotomy fixation in the First Affiliated Hospital of Xinjiang Medical University from February 2012 to December 2014. Imaging parameters were measured before fixation, immediately after fixation and during final fol ow-up. RESULTS AND CONCLUSION: (1) There were significant differences between preoperative and postoperative parameters except for pelvic incidence angle (P < 0.05). (2) There were significant differences between postoperative and last fol ow-up parameters except for Cobb angle, pelvic incidence angle, thoracic kyphosis angle and the thoracolumbar kyphosis (P < 0.05). (3) Pelvic tilt angle was negatively correlated with lumbar lordosis after fixation (r=-0.610, P < 0.001). Thoracic kyphosis was positively correlated with lumbar lordosis (r=0.598, P < 0.001). (4) Results suggested that lumbar sagittal contour can be significantly improved by corrective osteotomy for lumbar degenerative kyphosis. Simultaneously, reciprocal changes in the adjacent areas such as thoracic spine and pelvis occur to adapt to the new sagittal balance.
6.Analysis of colonoscopy results and treatment experience in 108 children
Danrong ZHU ; Weisong SHENG ; Bailian JIANG
Chongqing Medicine 2014;(29):3916-3917,3920
Objective To discuss the value and clinical significance of colonoscopy in children .Methods Colonoscopy was per-formed on 108 children with Olympus(PCF-Q260JI) .All polyps underwent electrocision .A retrospective study was performed in 108 children′s clinical and endoscopic examination data .Results 105 in 108 colonoscopy cases arrived at ileocesus successfully ,in which 98 cases were diseased .And the most common disease was colorectal polyps(65 cases) ,and 216 polyps were found .The 65 patients were performed resection in different ways ,and none bled and perforated;colorectal polyps were mainly single polyps .The lesions were often seen in proctosigmoid ,and mostly were juvenile polyps .Conclusion According to colonoscopy ,colorectal polyp is a important cause of disease .Colonoscopy is safe and reliable ,which can be very useful in diagnosis and treatment .
7.Effects of Baixiangdan capsule on learning and memory in PMS rat model with liver-qi invasion syndrome
Shaobo ZONG ; Dehao ZHU ; Sheng WEI
Chinese Pharmacological Bulletin 2015;(2):284-288,289
Aim To explore the effects of Baixiangdan capsule on learning and memory in PMS rat model with liver-qi invasion syndrome. Methods Liver-qi inva-sion rat model was prepared using foot-shock and noise stimulation, and then the model was treated with drugs, finally all the group of rats were evaluated using open-field test. We also detected learning and memory function of PMS liver-qi invasion rats model using Y-maze, new-object recognition and Morris water maze test. Results Compared with the normal group, the total distance increased significantly, number of crosses into the central area and duration of movement in the central area decreased significantly in model group. The total distance decreased significantly, number of crosses into the central area and duration of movement in the central area increased significantly in Baixiang-dan treatment group compared to the model group, and the total distance decreased significantly in fluoxetine treatment group compared to the model group. Com-pared with the normal group, DI decreased significant-ly in model group, and DI increased significantly in Baixiangdan treatment group. During place navigation training, the model group’ s escape latency was obvi-ously delayed on 2nd, 4th day. Compared with the model group, Baixiangdan and fluoxetine treatment group’ s escape latency was obviously reduced. During spatial probe test, compared with the normal group, the escape latency was obviously delayed, and the number of crossing platforms was significantly reduced in the model group. Compared with the model group, the number of crossing platforms significantly increased in Baixiangdan treatment group. Conclusion PMS liver-qi invasion rat model presents learning and memo-ry damage, which could be improved by Baixiangdan capsules, and the treatment effect may be superior to that of fluoxetine.
8.Analysis of image artifacts in computed radiographic system
Huayong ZHU ; Shufeng FAN ; Sheng XU
Chinese Medical Equipment Journal 1993;0(05):-
Objective To investigate the appearance,causes and countermeasures of the image artifacts in a computed radiographic system.Methods Random 1968 CR images were analyzed by GE Radworks.Results Among the 1,968 images which were choosed at random,66 images with artifacts were found and processed.The artifacts in computed radiographic system are relevant to system software and hardware,dust as well as operators.Conclusion Familiarization with the appearance and causes of CR image artifacts helps to prevent or reduce artifacts.
9.Effect of myricetin on migation and invasion ofhepatoma SMMC-7721 cells
Lei ZHU ; Weigan SHENG ; Zhengxin XU
Chinese Pharmacological Bulletin 2017;33(6):823-829
Aim To investigate the effects of myricetin on the migration and invasion of hepatoma SMMC-7721 cells.Methods SMMC-7721 cells were treated with different concentrations of myricetin.Migration and invasion of SMMC-7721 cells were examined by Wound healing and Transwell, and the expression of E-cadherin and N-cadherin was detected by RT-qPCR and Western blot.Results Myricetin may inhibit the viability of SMMC-7721 cells via different concentration(10~40 μmol·L-1);furthermore, myricetin might also inhibit the migration and invasion of hepatoma SMMC-7721 cells.Meanwhile with the increasing of myricetin concentration, both filopodia and lamellipodia formation was reducd, and 7721 cells displayed in more integrity.And data from RT-qPCR and Western blot demonstrated that myricetin may up-regulate the expression of E-cadherin, simultaneously, down-regulate N-cadherin in SMMC-7721 cells.Conclusion Myricetin may influence the cell migration and invasion through up-regulating the expression of E-cadherin, simultaneously, down-regulating N-cadherin and activate cytoskeleton remolding of SMMC-7721.