1.Antitumor efficacy of lymphocytes from hepatic porta lymph node stimulated by staphylococcal enterotoxin A
Chinese Journal of General Surgery 2001;0(07):-
ObjectiveTo evaluate the antitumor effects of lymphocytes from hepatic porta lymph node co cultured with staphylococcal enterotoxin A(SEA)?MethodsLymphocytes isolated from lymph node of 5 HCC patients were co cultured with SEA. The proliferation and cytotoxicity of the lymphocytes were observed. Flow cytometer was used to detect the expression of CD3?CD4 and CD8 on the surface of the lymphocytes. TNF ? and IFN ? released into the culture medium were measured by the method of ELISA. The results were compared with that yielded from TILs of the individual patients. ResultsCultured in the presence of SEA, there was a sharp rise of T cells, especially CD8 + cells. Cytotoxic activity was increased. TNF ? and IFN ? were predominantly produced in the first week.ConclusionsLymphocytes from lymph node activated by SEA were armed with an increased antitumor efficacy.
2.Study on the anti tumor activity of ginseng polysaccharide
Hua YANG ; Sheng HE ; Mingjiu YANG
Chinese Pharmacological Bulletin 1987;0(03):-
Rabbits were sensitized by Ginseng polysaccharide then the serum of the rabbits was collected and tested for the cytotoxity activity. The cytotoxic experiment in vitro revealed that the serum has cytotoxity in various degrees against maligant tumor cell lines of human and murine. The partly separated and purified immuned serum was injected into the Ehrlich 180 solid tumors of BALB/C mice. The fascinating hemorrhagic necrosis were find in the solid tumor. The bio-logical and physical feature of purified immuned serum were also analysed. The results indicate that the Ginseng polysaccharide can induce the endogenous production of TNF. The rabbit TNF was stable at 56℃ 30min. This results provided a reliable theoretic basis for the application of Ginseng polysaccharide in anti - tumor treatment.
4.Cytokine secretion of tumour Infiltrating lymphocytes stimulated by staphyloccocal enterotoxin A liposomes
Zhiyu LI ; Hua XUE ; Sheng HE ; Jiesho LI
Journal of Medical Postgraduates 2003;0(12):-
0.05) except that IFN-? secretion of L-SEA group was lower than that of SEA group at 4th day (P
5.Two cases with crush syndrome complicated with pulmonary edema.
Sheng HAO ; Guang-hua ZHU ; Wei-xun HE
Chinese Journal of Pediatrics 2009;47(5):391-392
Child
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Crush Syndrome
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complications
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Female
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Humans
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Male
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Pulmonary Edema
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complications
9.Microvenular hemangioma: report of a case.
Qian-he LIAO ; Hui-min AN ; Sheng-hua PAN ; Wei-hua LI
Chinese Journal of Pathology 2013;42(7):474-475
Actins
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metabolism
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Antigens, CD34
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metabolism
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Diagnosis, Differential
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Female
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Hemangioma
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metabolism
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pathology
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surgery
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Hemangiosarcoma
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pathology
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Humans
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Middle Aged
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Platelet Endothelial Cell Adhesion Molecule-1
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metabolism
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Sarcoma, Kaposi
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pathology
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Skin Neoplasms
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metabolism
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pathology
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surgery
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Vimentin
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metabolism