1.Application of fish oil in sepsis
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(01):-
Sepsis may result in a high mortality.Fish oil,which riches in?-3 polyunsaturated fatty acids,has anti-inflammatory and immune regulatory functions.?-3 fatty acids,which are special immune nutrient substrates,participate in the energy provision as well as improve organ function and regulate proinflammatory/anti-inflammatory cytokines.The ideal function of fish oil is associated with dosage,time of initiation and duration of application.
2.Relationship between lumbosacral multifidus muscle and lumbar disc herniation.
Wei-ye CHEN ; Kuan WANG ; Wei-an YUAN ; Hong-sheng ZHAN
China Journal of Orthopaedics and Traumatology 2016;29(6):581-584
As a common disease in clinical, the treatment of lumbar disc herniation (LDH) focused on local intervertebral disc, such as surgery and other interventional therapy treatment, but postoperative complications and recurrence rate has been a difficult problem in the field of profession. With the development of spine biomechanics and anatomy, researches on lumbar herniation also increased. Researchers discovered that the incidence and prognosis of LDH were inseparable with local muscle and soft tissue. As the deep paraspinal muscles, multifidus muscle plays an important role to make lumbar stability. Its abnormal function could reduce the stable of lumbar spine, and the chronic lumbar disease could also lead to multifidus muscle atrophy.
Animals
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Humans
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Intervertebral Disc Displacement
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physiopathology
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surgery
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Lumbosacral Region
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physiopathology
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surgery
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Paraspinal Muscles
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physiopathology
3.Impact factors of prognosis of spinal cord injury patients
Quan-sheng ZHAO ; Hong-hui SUN ; Wei WEI
Chinese Journal of Rehabilitation Theory and Practice 2002;8(11):693-694
ObjectiveTo explore the influence factors of prognosis of spinal cord injury patients. MethodsFollow-up data of 121 cases with spinal cord injury was analysed with retrospective cohort study.ResultsThe highest recover rate was in the patients who accepted the special rehabilitation therapy,while that of recovering two class was in the patients who accepted the magnetic stimulation.Conclusions Special recovering cure and magnetic stimulation can surely promote recovery of spinal cord injury patients.
4.Research progress of chemistry and anti-cancer activities of natural products from Chinese Garcinia plants.
Wen-Wei FU ; Hong-Sheng TAN ; Hong-Xi XU
Acta Pharmaceutica Sinica 2014;49(2):166-174
Garcinia plants are one of the rich sources of natural xanthones and benzophenones which have attracted a great deal of attention from the scientists in the fields of chemistry and pharmacology. Recently, many structurally unique constituents with various bioactivities, especially anti-tumor activity, have been isolated from Garcinia plants. This concise review focused on the anti-cancer activity natural products isolated from Chinese Garcinia plants, and the research finding by authors and collaborators over the past several years were cited.
Antineoplastic Agents, Phytogenic
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chemistry
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isolation & purification
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pharmacology
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Benzophenones
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chemistry
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isolation & purification
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pharmacology
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Cell Line, Tumor
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Cell Proliferation
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drug effects
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Drugs, Chinese Herbal
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chemistry
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isolation & purification
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pharmacology
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Garcinia
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chemistry
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classification
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Humans
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Inhibitory Concentration 50
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Molecular Structure
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Plants, Medicinal
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chemistry
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classification
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Structure-Activity Relationship
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Terpenes
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chemistry
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isolation & purification
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pharmacology
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Xanthones
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chemistry
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isolation & purification
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pharmacology
5.Unilateral multiple channels approach in percutaneous vertebroplasty for osteoporotic vertebral fractures.
Hong-yu WEI ; Ming-sheng TAN ; Li LIANG
China Journal of Orthopaedics and Traumatology 2013;26(12):1010-1014
OBJECTIVETo explore the therapeutic efficacy of unilateral multiple channels approach in percutaneous vertebroplasty (PVP) for osteoporotic vertebral fractures.
METHODSA retrospective review (from March 2003 to October 2012) was conducted on 685 consecutive patients, a total of 885 vertebrae were involved. Eighty-two cases (99 vertebrae) with bone cement leakage when less than 0.3 ml bone cement was injected to fill the fracture were given PVP procedure by unilateral multiple channels approach. 38 cases were male (45 vertebrae) and 44 cases were female (54 vertebrae). The average age was 75.4 years old (from 69 to 92). The operation time, amount of injected bone cement and complications were recorded. Rate of excellent and good outcomes was studied by measuring the cement distribution on the X-ray film. The visual analogue scale (VAS) score and Oswestry disability index (ODI) system were used to evaluate the pain relief and improvement of daily activity function respectively at preoperation and 1 hour, 1 month, 3 months and 6 months after operation.
RESULTSAll these ninety-nine vertebrae were treated in 82 cases with PVP of unilateral multiple channels approach. The average operation time was 33 minutes. The rate of excellent and good outcomes of cement distribution was 98.8%. The VAS score was (8.40 +/- 0.73) before surgery,and (2.50 +/- 0.43), (2.00 +/- 0.33), (1.80 +/- 0.28), (2.10 +/- 0.17) at 1 hour, 1 month,3 months and 6 months respectively after operation. ODI was (40.94 +/- 2.72) before surgery, (9.64 +/- 2.60) at 1 month after surgery, (8.52 +/- 2.30) at 3 months after surgery and (7.77 +/- 2.15) at the final follow-up. The differences of the VAS and ODI between pre-operation and post-operation had statistical significance (P<0.01). No spine or nerve injuries occurred intraoperatively.
CONCLUSIONThe unilateral multiple channels approach in percutaneous vertebroplasty can obviously relieve the pain and effectively improve the functional activity, provide a satisfied cement distribution in vertebral body with cement leakage after a small amount infusion.
Aged ; Aged, 80 and over ; Bone Cements ; Female ; Fractures, Compression ; surgery ; Humans ; Male ; Osteoporosis ; surgery ; Retrospective Studies ; Spinal Fractures ; surgery ; Treatment Outcome ; Vertebroplasty
9.Surgical treatment of upper cervical vertebra disease from high anterior cervical retropharyngeal approach
Chang-Sheng WANG ; Jian-Hua LIN ; Wei-Hong XU ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(12):-
Objective To study the clinical result of the surgical treatment of upper cervical vertebra disease from high anterior cervical retropharyngeal approach.Methods Among 14 patients,there were 7 C_(2.3)disc hernia- rions combined with C_(2.3)dislocations,3 Hangman fractures,2 odontoid process fractures and 2 C_3 tumors.All patients underwent the high anterior cervical retropharyngeal approach.10 cases were given discectomy of C_(2.3)or focus clear- ance of C_3,iliac bone autograft or titanium cage filled and internal fixation with titanium plate.2 cases of odontoid process fractures were given anterior screw fixation.Results 14 cases got successful exposure.The decompression, reduction,lesion clearance and fusion with internal fixation were done in all patients.There were no important vascu- lar or nerve injuries.The surgical treatment could improve the spinal cord nerve function to a certain degree for the cases with compression of spinal cord.Conclusion Good exposure of upper cervical spine and effective surgical oper- ation could be achieved from high anterior cervical retropharyngeal approach,with minimal trauma and complication, and it was a favorable approach.
10.Survival Analysis on a Follow-up Data of Patients with Primary Liver Cancer in Xuhui District of Shanghai
Shen-Sheng LI ; Hai-Yan GU ; Hong-Wei NI ;
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(05):-
Objective To investigate.the survival rates in a follow-up group of patient with primary liver cancer.Methods The follow-up data of new primary liver cancer cases between year 2001-2004 in Xuhui district was investigated.The age distribution of patients was described.Survival rate was analyzed with single and multiple Cox proportional hazards regression model,respectively.Results The age proportion distribution of patients showed double apexes with one in age 45~50 and another in age 70~75.The arithmetic mean of survival month was 16.4 with 95%CI 14.8~18.1 and median month was 6.9.It was no significance between male and female.Patients who had liver operation owned longer survival time,RR=0.315 5(95%CI 0.243 2~ 0.4093).The sutdy showed 5-year survival rate was 40.90%and 3.95%for patients with or without operation,respectively.It had no significant effect on survival time by gender,age and family history.Conclusion The screening test and intervention in high-risk people shall be done preferentially before peak age,so as to find primary liver cancer earlier,and the more patients can accept a suitable surgery care,the more they can obtain longer survival time.