1.Present situation of processing of traditional Mongolian medicine and its normalized suggestion.
Chao-Lu BAOLE ; Mei HONG ; A RUN ; Sheng-Sang NA
China Journal of Chinese Materia Medica 2014;39(16):3184-3186
The processing technology of traditional Mongolian medicine materials is distinctive, and it is one of the main characteristics of Mongolian pharmacy. Most of Mongolian medicines were used in the raw, but a quarter of medicinal materials need to be produced. Since ancient times, the processing of Mongolian medicine have cooperated with the Mongolian medicine clinical, which plays an important role in improving curative effect of Mongolian medicine and ensuring the safety of the drug. At present, the Mongolian medicines are processed still according to the traditional methods of the ancient literature method which has a lot of problems such as lag in technology, method of diversification, ambiguous indicators and unclear mechanism. Standardization of Mongolian medicine processing was based on traditional Mongolian medicine basic theory, which both projecting the characteristic, inheriting the traditional colleagues and reference to modern medicine, pharmacology, toxicology and other disciplines of knowledge. In this article, the processing situation, existing problem and standardization research of Mongolian medicine were described that providing a reference for the modernization and standardization of Mongolian medicine.
Chemistry, Pharmaceutical
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methods
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standards
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Drugs, Chinese Herbal
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chemistry
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standards
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Humans
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Medicine, Mongolian Traditional
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methods
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standards
2.Observation and nursing of airways in mechanically ventilated patients with ASOPP-induced respiratory failure
Cuiling LU ; Sheng TANG ; Jingtao LIU ; Yichun GONG ; Mei LI
Modern Clinical Nursing 2015;14(9):20-23
Objective To summarize the measures for nursing mechanical ventilated patients who suffered from respiratory failure caused by acute severe organophosphorus pesticide poisoning (ASOPP). Method Retrospectively, the nursing clinical data of 18 mechanically ventilated patients who suffered from ASOPP-induced respiratory failure in ICU from January 2013 to December 2014 were analyzed for summarizing the nursing measures concerning preventive extubation, airway humidification and sputum sucking, prevention of ventilator-associated pneumonia and final extubation. Result Sixteen ASOPP patients successfully recovered after hospital discharge and another two died from multiple organ function failure because of excessive pesticides. Conclusions Effective observation and nursing care of airways based on their characteristics in ASOPP patients including prevention of unexpected shedding , appropriate humidity of airways and prevention of infection of ventilator-associated pneumonia(VAP). All of these measures can reduce complications and contribute to the early recovery of patients.
3.Pulmonary alveolar microlithiasis: report of a case.
Hong-sheng LU ; Tao ZHOU ; Mei-fu GAN
Chinese Journal of Pathology 2007;36(5):348-349
Adult
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Biopsy
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Follow-Up Studies
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Humans
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Lithiasis
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diagnostic imaging
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pathology
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surgery
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Lung
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diagnostic imaging
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pathology
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surgery
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Lung Diseases
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diagnostic imaging
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pathology
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surgery
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Male
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Pulmonary Alveoli
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diagnostic imaging
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pathology
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surgery
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Tomography, X-Ray Computed
4.Biomechanical effects of osteoporosis vertebral augmentation on the adjacent intervertebral levels using a three-dimensional finite element analysis
Sheng LU ; Yong-Qing XU ; Mei-Chao ZHANG ;
Chinese Journal of Orthopaedic Trauma 2004;0(09):-
Objective To investigate effects of volume,distribution and leakage of bone cement in ver- tebroplasty on the adjacent intervertebral bodies using an experimentally calibrated and anatomically accurate fi- nite-element model of elderly L4-L5 vertebral bodies.Methods Computed tomography(CT)scanning was done,at 1 mm intervals,on L4-L5 vertebral bodies of the lumbar spine of an old man cadaver that had no abnormal findings on rnentgenograms.The L4-L5 motion segment data were obtained from the CT scans to establish in computer a three-dimensional finite element model of L4-L5 functional spinal unit(FSU)with the software Ansys 7.0.Compressive load after virtual vertebroplasty on the damaged model,unipedicular and bipedieolar injections and leakage of cement into the intervertebral space,and the resulting endplate and disc stresses of the adjacent vertebral bodies were analyzed in various spatial distributions of the filling material and different loading conditions. An anatomically accurate finite-element model of elderly L4-L5 vertebral bodies was developed.Results The FSU study suggested that changes in stress and strain at adjacent levels were minimal.Furthermore,endplale and disc stresses of the adjacent vertebral bodies were not influenced by bone cement filling volumes or distributions except under bending,whereas asymmetric distribution and leakage of bone cement to the disk increased the stress of adjacent endplates.Conclusion Since asymmetric distribution and significant leakage of cement into the intervertebral space can increase the stresses of endplates of adjacent vertebral bodies and may lead to a fracture, symmetric placement of cement in operation should be achieved and leakage of cement avoided.
5.Cardiac papillary fibroelastoma: report of a case.
Hong-Sheng LU ; Mei-Fu GAN ; Wen-Sheng HAN ; Han-Song CHEN
Chinese Journal of Pathology 2008;37(5):358-360
Adult
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Female
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Fibroma
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etiology
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Heart Neoplasms
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pathology
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physiopathology
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Humans
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Leiomyoma
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physiopathology
6.Control study of the ultrasonography with the placental vascular casts of the acardiac twins sequence
Xinlin CHEN ; Xiaohong YANG ; Peiwen CHEN ; Sheng ZHAO ; Qiaoying PENG ; Mei XIAO ; Xiaojun LU ; Lei ZHAO
Chinese Journal of Ultrasonography 2011;20(4):327-330
Objective To investigate the relationship between the ultrasonography diagnosis in prenatal and the postnatal placental vascular casts of the twins reversed arterial perfusion(TRAP) sequence. Methods Six cases of TRAP sequence underwent the two-dimensional and color Doppler ultrasonography, and performed placental vascular casts after termination of pregnance. Results According to the anatomical features and ultrasonography, there were 3 cases of acardius acephalus( IV) ,2 cases of acardius anceps( II ) , and 1 case of acardius acormus( I ). In all 6 cases,there were arterio-arterial and veno-venous anastomoses at the level of the chorionic plate between the normal co-twin and the acardiac twin,these anastmosis vessels were superficial and large calibre, and the distances of the placental insertions of the umbilical cords were different,4 cases <0. 5 cm, 2 cases were 4-5 cm. In 4 cases, the vessels entered and went out of the acardiac twin were just one large umbilical artery and one large umbilical vein. In 2 cases, the umbilical artery and umbilical vein had many vascular branches in the placenta. Out of 6 cases of the pump twin, 4 cases died,and 2 cases survived. Conclusions Ultrasonography was consistent with the placental vascular casts,the contrast observing gives us new information for the further research of the special type of the vascular anastmosis and prognosis of the TRAP sequence.
7.Microscopic thymoma: report of two cases.
Hong-sheng LU ; Mei-fu GAN ; Gang SUN ; Wei-fei CHEN
Chinese Journal of Pathology 2010;39(2):124-125
Adult
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Antibodies, Monoclonal
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analysis
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DNA Nucleotidylexotransferase
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metabolism
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Female
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Follow-Up Studies
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Humans
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Keratins
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immunology
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Male
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Middle Aged
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Prognosis
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Thymoma
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metabolism
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pathology
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surgery
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Thymus Neoplasms
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metabolism
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pathology
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surgery
8.Preliminary report of sunitinib as first line treatment in patients with metastatic renal cell carcinoma
Xinan SHENG ; Siming LI ; Zhihong CHI ; Lu SI ; Chuanliang CUI ; Mei HAN ; Jun GUO
Chinese Journal of Urology 2011;32(2):134-137
Objective To evaluate the efficacy and safety of sunitinib as first line treatment in patients with metastatic renal cell carcinoma (RCC). Methods This study included 46 Chinese patients who were diagnosed with metastatic RCC after radical nephrectomy. The patients received oral sunitinib (50 mg once daily on a 4 weeks on, 2 weeks off) on a 6 weeks cycle dose schedule until disease progression or intolerable toxicities occurred. Results The overall objective response rate was 32.6% (95% confidence interval [CI, 19.1% to 46. 1%]), and the disease control rate was 86.9%,with complete response (CR) 0 (0%), partial responses (PRs) 15 (32.6%), stable disease (SD) 25(54.3 %), and progression disease (PD) 6 ( 13. 1%). The median progression-free survival was 11 months, and the 1-year survival rate was 65.2%, while the median overall survival (mOS) has not been reached. The main adverse events included fatigue 33 (71.7%), skin discoloration 29 (63.0 %),anorexia 28 (60.9%), hand-foot syndrome 26 (56.5%), oral mucositis 25 (54.3%), hypertension 19 (41.3%), facial edema 18 (39.1%), diarrhea 17 (37.0%), hemorrhage 17 (37.0%), nausea 15 (32.6%), and hematological toxicity: leukopenia 32 (69.6%), neutropenia 30 (65.2%), thrombocytopenia 28 (60.9%), anemia 21 (45.7%). Most of grade 3/4 serious adverse events were thrombocytopenia in 15 (32. 6%) patients. Conclusions Sunitinib has a prominent effect in metastatic renal cell cancer in a Chinese population with mostly mild to moderate adverse reactions. More attention should be paid to grade 3/4 adverse reaction of thrombocytopenia.
9.Uterine epithelioid trophoblast tumor: report of a case.
Mei-fu GAN ; Chun-kai YU ; Hong-sheng LU ; Pei-nong YANG
Chinese Journal of Pathology 2007;36(8):570-571
Abdominal Neoplasms
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secondary
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surgery
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Abdominal Wall
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Antiporters
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metabolism
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Choriocarcinoma
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pathology
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Diagnosis, Differential
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Epithelioid Cells
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pathology
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Female
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Gestational Trophoblastic Disease
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metabolism
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pathology
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secondary
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surgery
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Humans
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Pregnancy
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Uterine Neoplasms
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metabolism
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pathology
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surgery
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Young Adult
10.Study of EML4-ALK fusion gene as a biomarker in non-small cell lung cancer.
Lu WANG ; Yao-hui WANG ; Chun-yang LIU ; Mei HAN ; Shu-peng ZHANG ; Ren-sheng LAI
Chinese Journal of Pathology 2011;40(11):788-790
Biomarkers, Tumor
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metabolism
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Carcinoma, Non-Small-Cell Lung
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drug therapy
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metabolism
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pathology
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Humans
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Lung Neoplasms
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drug therapy
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metabolism
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pathology
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Oncogene Proteins, Fusion
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chemistry
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metabolism
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Protein Kinase Inhibitors
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therapeutic use
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Pyrazoles
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therapeutic use
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Pyridines
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therapeutic use
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Pyrimidines
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therapeutic use
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Smoking