2.Mechanism of inhibition of tumor metastasis by breast cancer metastasis suppressor 1
Journal of International Oncology 2011;38(6):438-441
Breast cancer metastasis suppressor 1(BRMS1)can suppress the tumor cells metastasis. and significantly reduces the metastasis without affecting tumor growth. The relevant mechanism(s)may be related to intercellular communication, phosphoinositide signal transduction and interaction with NF-KB, and so on. Therefore, exploring the mechanisms of inhibition of tumor metastasis might be helpful for use of BRMS1 as tumor gene therapy.
3.Signal processing of totally digitalized B-ultrasonography
International Journal of Biomedical Engineering 2006;0(06):-
Totally digitalized B-ultrasonography is the tendency of the development of ultrasonic medical instruments. Its basic technical characteristic is realizing real-time processing of the extremely huge ultrasonic data with digital electric circuit. This paper summarized the tendency of development and the primary techniques of signal processing, which including dynamic filtering, log amplification, envelope detection and secondary sampling. Furthermore, various techniques in different procedure of signal processing are introduced in detail.
6.Development of hospital infection data sharing platform based on J2EE technique
Peng, ZHOU ; Xin, ZHOU ; Dong-Sheng, ZHAO
Bulletin of The Academy of Military Medical Sciences 2009;33(6):561-563,566
Objective:To establish hospital infection data sharing and service platform for collecting and issuing the hospital infection data. Methods:The relational database was used to realize data storage and J2EE light structure was employed to enhance the development and the operating efficiency and flexibility of the system according to the principles of Web information system.Results and Conclusion:An open and sharing hospital infection data platform for data processing, retrieving and analyzing was established. The established hospital infection data set and surgery infection data set contained more than 20 000 records. The system provided an effective software platform support for the utilization of hospital infection data and the prevention and control of hospital infection. This article introduces key technologies of the design and realization of the system.
7.Application of transbronchial lung biopsy in pneumoconiosis diagnosis.
Lin MAO ; Ze-sheng ZHOU ; Jin SHI
Chinese Journal of Industrial Hygiene and Occupational Diseases 2012;30(4):301-304
Adult
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Biopsy
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methods
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Bronchoscopy
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Humans
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Lung
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pathology
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Male
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Middle Aged
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Pneumoconiosis
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diagnosis
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pathology
8.Building a nursing team at a new hospital
Jiehua SHENG ; Minyan ZHOU ; Xiulan SHEN
Chinese Journal of Hospital Administration 2013;(1):48-51
The paper described the building of a nursing team in a newly built hospital.The process consists of setting up the nursing department in advance and developing rules and regulations;enhancing nurse rotations and training to enhance their professionalism; building a seamless communication to make a supportive environment and sense of belongings; enhancing education of professional spirit to train the nurses to respect their career.All these provide the hospital with solid support of nursing team building.
9.Analysis of Cis-acting Elements on Respiratory Mucin MUC5AC Expression and Regulation in Pulmonary A549 Cell Line
Sheng-Jin LI ; Xiang-Dong ZHOU ;
China Biotechnology 2006;0(02):-
Objective:To study the mechanisms of neutrophil elastase (NE) induced expression of respiratory mucin MUC5AC. Methods:Using gene recombination techniques,four luciferase reporter gene plasmids containing different length of human MUC5AC gene promoter were constructed.Site-directed mutagenesis technique was used to establish mutants of Sp-l and NF-?B site in MUC5AC gene promoter; the relative luciferase activities were detected in the transfected human pulmonary A549 cells. Results:Series of luciferase reporter gene containing different sequences of human MUC5AC promotor were constructed successfully.NE could increase the expression of luciferase reporter gene plasmid containing -1300bp,-689bp and-324bp version of MUC5AC promoter in the transfected A549 cells (P
10.Clinical manifestations and laryngoscopic characteristics of the laryngeal amyloidosis
Tao ZHOU ; Jianfei SHENG ; Yang JIANG ;
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(11):-
OBJECTIVE TTo evaluate the clinical manifestations of the laryngeal amyloidosis and its laryngoscopic characteristics.METHODS The clinical data of 11 cases with laryngeal amyloidosis confirmed pathologically was studied retrospectively. RESULTS There were 4 males and 7 females in this study.The age of the patients ranged from 16 to 64 years old (average 43.36?4.16).The duration of symptoms was 4 months to 10 years (average 2.85?0.87 years).Hoarseness presented in 10 patients (90.90%) and dyspnea in 4 patients.The false vocal cord was involved in 8 patients,laryngeal ventricle in 6 patients,true vocal cord in 5 patients and subglottic area in 3 patients observed with fibrolaryngoscope. The appearance of the lesions was mainly described as waxy yellow or yellow-gray submucosal plaques and nodules without ulceration of the overlying mucosa.The laryngostroboscopy demonstrated that the wave of the mucosa and vibration of the involved vocal cords were adynamic or disappeared.CONCLUSION The chief complaint of the laryngeal amyloidosis was hoarseness. Laryngeal amyloidosis is a slowly progressive disease. The lesions commonly involve the false vocal cord, laryngeal ventricle,true vocal cord and subglottic area.