2.Association between metabolic syndrome and prostate volume
Chinese Journal of Geriatrics 2012;31(11):935-937
Objective To evaluate the relationship between parameters of MS and prostate volume.Methods A total of 843 men aged 30 to 49 years were enrolled from August 2008 to July 2011.Prostate volume by ultrasonography,serum prostate specific antigen,digital rectal examination,urinary analysis,and MS-related parameters were investigated.We evaluated the correlations of prostate volume with MS and MS components.Results Prostate volume was largerin the MS group (28.3±5.5 ml) than in the non-MS group (23.2±5.6 ml,P<0.05).The prostate volumes in subjects with abnormal levels of fasting plasma glucose (FPG) (25.4±5.5 ml),body mass index (BMI) (25.4±5.3 ml) and waist circumference (30.2±4.8 ml) were increased compared with those of subjects with normal parameters (23.6±5.5 ml,22.6±5.5 and 23.5±5.3 ml,respectively,all P<0.05).The liner regression analysis showed that the FPG,BMI,WC,systolic pressure and triglyceride had a positive correlation with the prostate volume(r=0.216,0.397,0.411,0.170,0.184,respectively; all P<0.05),but negatively related to HDL-C(r=-0.107,P<0.05).Conclusions The patients with abnormal FPG,BMI and waist circumference have larger prostate volume.
3.Strategies of catheter ablation of persistent atrial fibrillation.
Chinese Medical Journal 2013;126(14):2603-2606
4.Case of primary thrombocythemia.
Sheng MA ; Zhiqiang LIU ; Yongchen MA
Chinese Acupuncture & Moxibustion 2015;35(12):1266-1266
5.How to perform the follow-up analysis of visual field test
Ophthalmology in China 1993;0(01):-
In the course of follow-up analyses of visual field test,it should take more than two visual field tests that had similar results as baseline test,and some factors should be taken into account,such as accordant testing conditions,reliable indeces,test errors and fluctuation effects,and so on.The indeces of Mean Deviation(MD)and Pattern Standard Deviation(PSD)could reflect the whole change trend of follow-up visual field test,while sensitivity value of every point and their pattern deviations could help to analyse tiny changes of visual field tests.Those statistic softwares provided by automatic perimetry should be used adequately.Through the follow-up analyses of visual field test,glaucoma doctors could adjust therapy schemes in time in order to obtain objective intraocular pressure and stabilize visual field and glaucoma.
6.Clinical effect of partial reduction orthokeratology and spectacles on high myopia adolescents
Ming, LUO ; Sheng-Sheng, MA ; Hong-Yang, LI
International Eye Science 2015;(1):128-130
Abstract? AlM: To observe the effect of combining partial reduction orthokeratology ( Ortho-K ) and spectacles on slowing myopic progressionin high myopic adolescent.? METHODS: Sixty - nine eyes of 36 high myopic adolescent ( aged 9 ~15 years ) with spherical equivalent refraction ≧-6. 00 diopters ( D) ( spherical component≧-5. 50D) were fitted with custom-made four-zone/five-curve Ortho-K lenses. The target of reduction was to achieve -5. 00D for both eyes. The residual refractive errors after at least one month of Ortho-K wear were corrected with single-vision spectacles for clear vision in the daytime. The unaided visual acuity ( UVA) , refractive error ( RE ) , axial length ( AL ) , and ocular health were assessed before the Ortho-K lens wear, and followed up for 2a after Ortho-K.?RESULTS: ( 1 ) Changes in UVA: The mean UVA was 0. 09±0. 05 at baseline before Ortho-K;the mean UVA was 0. 27 ± 0. 14, 0. 54 ± 0. 18, 0. 78 ± 0. 24, and 0. 81 ± 0. 19, respectively after Ortho-K wear for l night, 1wk, 1, and 3mo. The differences of UVA were significant with baseline (P<0. 05), and became stable 1mo after the treatment. (2) Changes in RE:The mean RE was -6. 82± 0. 71D at baseline before Ortho-K and -6. 86 ± 0. 77D after Ortho-K wear for 1a (P>0. 05 compared to baseline). The mean RE was-7. 11±0. 81D after Ortho-K wear for 2a, and the amount of myopia increased -0. 29 ± 0. 37D compared to baseline (P<0. 05). (3) Changes in AL: The mean AL was 26. 18 ± 0. 57mm at baseline before Ortho-K, and it was not significantly different (P>0. 05) from the AL after Ortho-K wear for 6mo (26. 19±0. 54mm) and for 1a (26. 21± 0. 47mm). The AL was 26. 37±0. 59mm after Ortho-K wear for 2a, and the mean increase was 0. 19 ± 0. 28mm compared to baseline (P<0. 05). (4) Grade 1 corneal staining was observed in some subjects at each visit. However, the staining was improved after lens cleaning, discontinuing lens wear, or applying artificial tears. No other adverse events were reported in all subjects during the 2a study.?CONCLUSlON:Combining partial reduction Ortho-K and spectacles completely slowed myopic progression in high myopic adolescent after receiving the treatment for 1a, and partially reduced myopia progression after 2a of treatment. No severe ocular complications were found throughout the treatment. The combination treatment appeared to be effective and safe, but its long-term effect needs to be further assessed.
7.The expression of SQS1 gene and the content of glycyrrhizic acid of Glycyrrhiza uralensis Fisch. in different concentrations of Mn2+.
Acta Pharmaceutica Sinica 2015;50(1):111-117
The transplants of one-year-old Glycyrrhiza uralensis Fisch. were subjected to five concentrations of MnSO4-H2O (0, 1.81, 18.1, 36.2 and 54.3 mg·L(-1)) culturing in vermiculite. qRT-PCR and HPLC were respectively used to measure the relative expression of SQS1 gene and the content of glycyrrhizic acid of G. uralensis in different concentrations of MnSO4·H2O. This is to explore discuss the effects of the expression of SQS1 gene and the accumulation of glycyrrhizic acid by Mn treatment. The results showed both the expression of SQS1 gene and the content of glycyrrhzic acid of G. uralensis tended to rise after the fall of the first with the increase of concentration of Mn treatment. And they were of very significant positive correlation (P<0.01, r=0.737). Relative expression of SQS1 gene reached the highest 7.90 under 18.1 mg·L(-1) MnSO4·H2O treatment. It was very significantly different between 18.1 mg·L(-1) concentration of MnSO4·H2O treatment and CK (0 mg·L(-1)), 1.81, 36.2 and 54.3 mg·L(-1) (P<0.01), and 1.75, 1.37, 1.37, 2.33 times respectively. The content of glycyrrhizic acid reached the highest under 1.81 and 18.1 mg·L(-1) MnSO4·H2O treatment, and there were not significant difference (P>0.05). It was very significantly different between them and other concentrations of MnSO4·H2O treatment (P<0.01). This study suggests the appropriate concentration of Mn treatment could certain promote the expression of SQS1 gene and the accumulation of glycyrrhizic acid of G. uralensis.
Chromatography, High Pressure Liquid
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Genes, Plant
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Glycyrrhiza uralensis
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chemistry
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genetics
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Glycyrrhizic Acid
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analysis
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Manganese