Abstract? AlM: To observe the effect of combining partial reduction orthokeratology ( Ortho-K ) and spectacles on slowing myopic progressionin high myopic adolescent.? METHODS: Sixty - nine eyes of 36 high myopic adolescent ( aged 9 ~15 years ) with spherical equivalent refraction ≧-6. 00 diopters ( D) ( spherical component≧-5. 50D) were fitted with custom-made four-zone/five-curve Ortho-K lenses. The target of reduction was to achieve -5. 00D for both eyes. The residual refractive errors after at least one month of Ortho-K wear were corrected with single-vision spectacles for clear vision in the daytime. The unaided visual acuity ( UVA) , refractive error ( RE ) , axial length ( AL ) , and ocular health were assessed before the Ortho-K lens wear, and followed up for 2a after Ortho-K.?RESULTS: ( 1 ) Changes in UVA: The mean UVA was 0. 09±0. 05 at baseline before Ortho-K;the mean UVA was 0. 27 ± 0. 14, 0. 54 ± 0. 18, 0. 78 ± 0. 24, and 0. 81 ± 0. 19, respectively after Ortho-K wear for l night, 1wk, 1, and 3mo. The differences of UVA were significant with baseline (P<0. 05), and became stable 1mo after the treatment. (2) Changes in RE:The mean RE was -6. 82± 0. 71D at baseline before Ortho-K and -6. 86 ± 0. 77D after Ortho-K wear for 1a (P>0. 05 compared to baseline). The mean RE was-7. 11±0. 81D after Ortho-K wear for 2a, and the amount of myopia increased -0. 29 ± 0. 37D compared to baseline (P<0. 05). (3) Changes in AL: The mean AL was 26. 18 ± 0. 57mm at baseline before Ortho-K, and it was not significantly different (P>0. 05) from the AL after Ortho-K wear for 6mo (26. 19±0. 54mm) and for 1a (26. 21± 0. 47mm). The AL was 26. 37±0. 59mm after Ortho-K wear for 2a, and the mean increase was 0. 19 ± 0. 28mm compared to baseline (P<0. 05). (4) Grade 1 corneal staining was observed in some subjects at each visit. However, the staining was improved after lens cleaning, discontinuing lens wear, or applying artificial tears. No other adverse events were reported in all subjects during the 2a study.?CONCLUSlON:Combining partial reduction Ortho-K and spectacles completely slowed myopic progression in high myopic adolescent after receiving the treatment for 1a, and partially reduced myopia progression after 2a of treatment. No severe ocular complications were found throughout the treatment. The combination treatment appeared to be effective and safe, but its long-term effect needs to be further assessed.

Adenocarcinoma, Clear Cell ; pathology ; Adult ; Female ; Humans ; Thyroid Neoplasms ; pathology

Adult ; Aged ; Body Mass Index ; Case-Control Studies ; Humans ; Male ; Middle Aged ; Neck ; anatomy & histology ; Sleep Apnea, Obstructive ; pathology ; physiopathology ; Young Adult

Adolescent ; Electrocardiography ; Female ; Humans ; Myocarditis ; complications ; physiopathology ; Tachycardia, Ventricular ; etiology ; physiopathology

Objective To analyze the clinical features,etiology and antibiotics-resistance in purulent meningitis cases identified in our hospital during the recent 5 years.Methods Clinical data were collected and the etiology and antibiotics-resistance were analyzed in 36 children with purulent meningitis during Jan 2007 to Oct 2011,and all cases were identified by a positive cerebrospinal fluid culture.Results There were 2 267 cerebrospinal fluid samples cultured and only 36 samples showed positive results and the rate was 1.6％,and 27 strains (75.0％,27/36) were Gram positive cocco bacteria.The most common bacterium was coagulase negative Staphylococcus and the ratio was 50.0％ (18/36),followed by Escherichia coli ( 13.9％,5/36),Streptococcus pneumonia ( 11.1％,4/36) and Staphylococcus aureus ( 8.3％,3/36).Drug sensitive test showed that 95.2％ of the Staphylococcus was β-lactamase positive and resistant to penicillin,and 33.3％ were sensitive to oxacillin.The death rate was 13.9％ (5/36).Conclusion Staphylococcus,Escherichia coli and Streptococcus pneumonia are the top three pathogens causing purulent meningitis in children in our hospital,and clinicians should choose antibiotics according to the result of drug sensitive test.

ObjectiveTo study the factors associated with meningioma peritumoral edema.MethodsPeritumoral edema of 18 patients was assessed on a semi - quantitative form from preoperative radiography. All the patients' clinical information( tumor size, tumor envelope damage, brain surface vein compression, pathological type), malignancy of tumor tissue, vascular endothelial growth factor(VEGF), immuno-histo-chemisty stain were studied to find out the correlation with peritumoral edema. Results There was no correlation between tumor size, pathological type and brain vein compression with peritumoral edema。 Tumor envelope damage and VEGF immunoreactivity were strongly associated with peritumoral edema. ConclusionThese data suggest that meningioma peritumoral edema may bea result of tumor cell producing VEGF in combination with tumor envelope damage, which lead to the damage of normal blood brain barrier and the enterance of edema-causing chemical factor.

Objective To explore the safety and invasion of endoscopic thyroidectomy(ET).Methods A total of 156 cases of benign thyroid diseases were surgically treated from January 2003 to December 2005,including 64 cases of endoscopic thyroidectomy(Endoscopic Group) and 92 cases of traditional thyroidectomy(Traditional Group).The operation time,hemorrhage volume,length of incision,Visual Analogue Scale(VAS) scores for pain severity and cosmetic appearance,analgesic requirements,postoperative hospital stay,hospitalization costs,wound infection rate,and recurrent rate were compared between the two groups,respectively.Results The operation was successfully completed in both of groups.No hemorrhage,hoarseness,or hypocalcemia was encountered.Wound hydrops occurred in 4 cases in the Traditional Group.As compared with the Traditional Group,the Endoscopic Group had less blood loss(15?10 ml vs 20?15 ml;t=-2.330,P=0.021),lower VAS pain scores(2.5?1.0 vs(5.0?)1.6;t=-11.079,P=0.000),higher VAS cosmetic scores(8.0?1.5 vs 2.0?1.2;t=27.696,P=0.000),and less analgesic requirements(10 cases vs 28 cases;?~2=4.493,P=0.034),but longer operation time(80?20 min vs 70?30 min;t=2.330,P=0.021) and higher hospitalization costs(5 352.7?978 yuan vs 4 738.5?672 yuan;t=4.651,P=0.000).Follow-up observations for 2~30 months(mean,13 months) revealed recurrence in 2 cases in the Endoscopic Group and 3 cases in the Traditional Group.Conclusions As compared with traditional operation,endoscopic thyroidectomy has advantages of minimal invasion,early recovery,short hospitalization time,and high safety,being an ideal option for benign thyroid diseases.

Objective: To study the clinical features of depressive patients consulting neurological clinics in a general hospital and the therapeutic effect of Paroxetine in treatment of depression in this group Methods: 46 patients with depressive symptoms were collected consecutively, 24 among them were treated by Paroxetine The changes of scores of HAMD and Clinical Global Impression(CGI) before and after treatment were used to assess the therapeutic effect Results: Patients complained a variety of somatic symptoms involved nearly all systems, After four weeks’treatment of Paroxetine, both HAMD and CGI scores decreased dramatically The change of HAMD became significant at the end of the first week of treatment Conclusion: Depressive patients consulting general hospital have many somatic complaints Paroxetine has both anxioletic and antidepressant effects in this group of patients

Objective To explore the feasibility and reliability of laparoscopic assisted thyroidectomy. Methods A transversal 2.0 cm incision was made at the site 1.0 cm above the sternal notch. By using a harmonic scalpel under a 5 mm laparoscope, the thyroid glands and involving blood vessels were dealt with by either “coagulation-dissection-suction” technique or “dissection-coagulation-disconnection” technique to complete thyroid enucleation or lobectomy. Results There were 20 cases of adenoma (nodule) excision and 6 cases of unilateral lobectomy. The operation time was 80~130 min (mean, 100 min). The intraoperative blood loss was 10~40 ml (mean, 20 ml). No surgical complications occurred. Follow-up checkups in 23 cases for 1~)20 months (mean, 9 months) found a satisfactory cosmetic result and no recurrence. Conclusions Thyroidectomy under laparoscope is safe and reliable. This procedure offers a shorter incision, less invasion and better cosmetic results as compared with conventional thyroidectomy.

Objective To report and evaluate the treatment results of unstable distal radial fractures with volar locking compression plate (LCP). Methods 46 cases of unstable fractures of distal radius were treated with open reduction and LCP fixation through volar approach from April 2002 to May 2004. 14 of which underwent bone graft and 12 postoperative immobilization with plaster sprint. Results A follow-up of 6 to 30 (mean 21) months revealed bone union in all cases with a mean volar deviation angle of 9.7?and a mean ulna deviation of 21.3?of the distal radius. The wrist functions were evaluated by the modified Gartland and Werley system only to find 32 excellent cases, 11 good ones, 2 fair ones, and 1 poor one. Conclusions The unstable distal radial fractures can effectively be treated with open reduction and LCP fixation through volar approach. The subsidence of the radial articular surface can well be prevented and bone healing accelerated with supplementary bone graft.