1.Investigation in mental health level and coping style in emergency nurses
Qunying TANG ; Sheng LE ; Famei LIU
Chinese Journal of Practical Nursing 2009;25(12):3-5
Objective To investigate of mental health level and coping style in emergency nurses. Methods Investigations were conducted in 78 emergency nurses who had been m the emergency department over one year from 4 general hospitals in Huizhou using general condition questionnaire, symptom checklist 90 (SCL-90) and simple coping style questionnaire, the results underwent analysis. Results The subfactor score of SCL- 90 was significantly higher than that of Chinese norm. Emergency nurses adopted positive coping style more then conunon adillt group. The positive coping style of nurses was negatively correlated with the total score of SCL-90, somatization, interpersonal relationship, depression and anxiety factor of SCL-90. The negative coping style was positively correlated with the total score, sornatization, depression and anxiety factor of SCL-90.Conchusions Emergency nurses have poor mental health. We must adopt effective means to improve theirs mental health level.
2.Application of biomarkers in research of breast cancer
ping, GU ; shi-le, SHENG ; gang, HUANG
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(11):-
Breast cancer is by far the most common cancer for females.The recent researches focus on early diagnosis,optimal adjuvant therapy and curative effect surveillance.The paper summarizes the application of tissue and fluid tumor markers in the diagnosis,treatment,curative effect surveillance and prognostic prediction of breast cancer,which include widely-accepted estrogen receptors,HER2-neu and CA15-3,and novel ones such as Cyclin E,TIMP-1,RAR-?,hK10 and BRCA-1.
3.Clinical Study on Infantile Congenital and Non-Congenital Cytomegalovirus Infection
rong, MI ; fang-sheng, XU ; cong-le, ZHOU
Journal of Applied Clinical Pediatrics 2006;0(22):-
Objective To learn the damage on infants and effect of treatment of congenital cytomegalovirus(CMV) infection and non-congenital cytomegalovirus infection which included perinatal infection and postnatal infection.Methods According to the diagnosis standard of cytomegalovirus infection in China,46 infants diagnosed CMV infection were retrospectively reviewed.In this research,CMV infection was diagnosed if serum CMV-IgM or CMV-pp65 in polymorphous leukocytes was positive.According to beginning time of CMV infection symptom,46 cases were divided into 2 groups: congenital infection and non-congenital infection,clinical features of 2 groups were compared.Ganciclovir was given to the infants with infantile hepatic syndrome of 2 groups,and compared liver transaminases and bilirulin with itself after treatment,side-effect was observed.Infants of 2 groups were followed up,and prognosis was compared.Results In 46 infants,21 were enrolled congenital infection group,25 were non-congenital infection group.CMV-IgM was positive in 38 cases of 46 patients,CMV-pp65 was positive in 19 cases of 43 patients,both CMVIgM and CMV-pp65 were positive in 11 cases.More congenital malformation were found in congenital group than non-congenital group,there was significant difference between 2 groups((P
4.Genetics and clinical features of dystonia
xiao-jie, ZHANG ; sheng, CHEN ; wei-dong, LE
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(07):-
Dystonia is a common movement disorder characterized by abnormal gestures and involuntary movement as a result of incoordinate contraction of agonistic and antagonistic muscles.The underlying pathogenesis is very complicated and there are various clinical manifestations.The recent findings in genetics and clinical features of primary dystonia,dystonia-plus syndrome and heredodegenerative dystonia are introduced in this paper.
5.On Construction of Art Mass Organization in Medical Colleges
Dan BA ; Le-Ban NONG ; Hua-Sheng WANG ;
Chinese Journal of Medical Education Research 2006;0(07):-
The construction of art mass organization in medical colleges can consummate quality education system,make up insufficiency of the classroom teaching,promote medical students' comprehensive development and innovative ability and mold fine mind and lofty medical ethics.Therefore,it has important theoretical and practical significance to study existing problems and find out the ways to improve art mass organization construction of medical schools.
6.Ethological changes in rats with chronic stress-induced anxiety and interventional effect of Danzhixiaoyao Powder
Ning LI ; Qi-Sheng TANG ; Rui-Zhen ZHAO ; Sheng-Le GOU
Journal of Beijing University of Traditional Chinese Medicine 2009;32(12):826-829
Objective To investigate the interventional effect of Danzhixiaoyao Powder from the aspect of ethology in rats with chronic stress-induced anxiety.Methods The rat model of chronic stress-induced anxiety was established by using the stimulation of uncertainty empty bottle.The changes of exploratory,grooming and attack behaviors were observed when rats were stimulated by empty bottle.After the stress the ethology of rats were reviewed by applying international elevated plus-maze(EPM)test.The interventional effect of Danzhxiaoyao Powder was observed.Results The rats were irritable after the stress and had frequency grooming and attack behaviors.The result of EPM test showed that the rats were not wiBing to enter or stay in the open arm,but tended to explore the block arm and stay in there for a longer time.The motor activity of the rats decreased.After the intervene of Danzhixiaoyao Powder the grooming and attack behaviors of rats were reduced significantly,the total motor activity increased,and exploring times and stay time in the open ann were improved.Conclusion The model of chronic psychological stress by the stimulation of uncertainty empty bottle simulates well the anxiety in rats etiologically.Danzhxiaoyao Powder has a significant anti-anxiety effect.
7.Expression of cancer stem cell antigens, prostate stem cell antigen and Oct-4, and its clinicopatholgical significances in benign and malignant lesions of gallbladder.
Le-Ping YANG ; Zhu-Lin YANG ; Jiang-Sheng HUANG ; Xi FU
Chinese Journal of Pathology 2008;37(1):56-57
Antigens
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immunology
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Antigens, Neoplasm
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drug effects
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immunology
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metabolism
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Gallbladder Neoplasms
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immunology
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metabolism
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pathology
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Gene Expression Regulation, Neoplastic
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Humans
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Male
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Neoplastic Stem Cells
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immunology
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Octamer Transcription Factor-3
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genetics
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metabolism
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Prostatic Neoplasms
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genetics
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metabolism
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pathology
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Tumor Cells, Cultured
9.Effects of Hypericum perforatum L. extract on anti-stress response. In normal mice and antioxidant activity in exhaustive exercise mice.
Ting-Ting YE ; Le LI ; Ying-Ying LIAO ; Ji-Zhong YAN ; Sheng-Qiang TONG
Chinese Journal of Applied Physiology 2014;30(4):332-334
Animals
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Antioxidants
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metabolism
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Fatigue
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blood
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Female
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Hypericum
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chemistry
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Male
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Mice
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Mice, Inbred ICR
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Physical Conditioning, Animal
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Plant Extracts
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pharmacology
10.A new cyclic diarylheptanoid from the bark of Myrica rubra.
Sheng-nan SHEN ; Fang-bo XIA ; He LI ; Ya-min LIU ; Rui-le PAN
Acta Pharmaceutica Sinica 2015;50(6):746-748
To study the chemical constituents from the bark of Myrica rubra, fourteen compounds were isolated from the methanolic extract using various chromatographic techniques, including silica gel, Sephadex LH-20 and preparative HPLC. Their structures were identified on the basis of chemical properties and spectroscopic data, as 3, 5-dimethoxy-4-hydroxymyricanol (1), myricanol (2), myricanone (3), myricanol 11-sulfate (4), myricitrin (5), quercetin (6), quercetin-3-rhamnoside (7), tamarixol (8), uvaol (9), ursolic acid (10), taraxerol (11), myricadiol (12), β-sitosterol (13) and β-daucosterol (14). Among them, compound 1 is a new compound, named as 3, 5-dimethoxy-4-hydroxymyricanol, compounds 8, 9 were isolated from the genus Myrica for the first time.
Diarylheptanoids
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chemistry
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isolation & purification
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Myrica
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chemistry
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Phytochemicals
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chemistry
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isolation & purification
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Plant Bark
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chemistry