1.Clinical Research on Correlation between SOD and TXB_2/6-k-PGF_(l?) in Stroke Patients
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(11):-
Objective To research the correlation between SOD and TXB2/6-k-PGF1? and relationship with TCM syndrome in stroke patients. Methods A contrast test on blood SOD and plasma TXB2 and 6-k-PGF1? was given separately to two groups, one group was 74 cases with stroke and the control group was 36 cases in health. Results Content of b1ood SOD in stroke group reduced remarkably compared with the health group (P
4.Application of circulating tumor cells detection in non-small cell lung cancer
Hao LI ; Sheng LI ; Baijiang ZHANG
Journal of International Oncology 2015;(4):298-300
Circulating tumor cells(CTCs)are essential for establishing metastasis and recurrence in non-small cell lung cancer(NSCLC). With the development of detection technique,results from recent studies suggest that CTC level could be a supplement for TNM staging system and a prediction marker of prognosis and therapeutic efficacy,and even could be applied for risk assessment of early NSCLC. Furthermore,as a non-invasiveliquid biopsy,detection of CTC can reflect the molecular biology and genetics characteristics of the primary tumor,and subsequently assist in selecting an optimal individualized treatment.
6.The investigation and progress of the cellular and molecular biological mechanisms of Tripterygium wilfordii in treating rheumatoid arthritis.
Zhe CHEN ; Rui-Lin LI ; Sheng-Hao TU
Chinese Journal of Integrated Traditional and Western Medicine 2009;29(2):183-186
Anti-Inflammatory Agents, Non-Steroidal
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pharmacology
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therapeutic use
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Apoptosis
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drug effects
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Arthritis, Rheumatoid
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drug therapy
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immunology
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B-Lymphocytes
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drug effects
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Cytokines
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drug effects
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Drugs, Chinese Herbal
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pharmacology
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therapeutic use
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Humans
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Immunosuppressive Agents
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pharmacology
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therapeutic use
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Phytotherapy
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T-Lymphocytes
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drug effects
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Tripterygium
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chemistry
9.Pulmonary manifestation in children with systemic lupus erythematosus
Sheng HAO ; Juan WANG ; Weixun HE ; Wenyan HUANG ; Guanghua ZHU
Chinese Journal of Applied Clinical Pediatrics 2014;29(21):1628-1631
Objective To observe the incidence,clinical types,and prognosis of pulmonary involvement in children with systemic lupus erythematosus(SLE),and to probe the relationship between the relative factors.Methods The clinical data of 61 children with SLE,who treated in Children's Hospital of Shanghai from Jan.2006 to Dec.2011 were analyzed retrospectively.The lung manifestations of the patients were classified according to their clinical symptoms and signs,and lung imaging examination (chest X-ray and CT).Other data of the SLE patients with lung injury or without lung injury were collected,including the course of the disease,activity index [SLE disease activity index (SLEDAI) scoring 0-4 was divided into no activity,5-9 was divided into low activity,10-14 was divided into moderate activity,and more than 15 as severe activity],blood sedimentation,the values of serum complement and the positive rate of dsDNA in autoantibody,and a comparison was made and statistical analysis was performed.Results Pulmonary injury occurred in 17 cases with an incidence rate of 27.9% (17/61 cases),and the average course of the disease was (8.76 ± 6.96) months.The clinical manifestations of 17 cases included fever,cough,dyspnea,hypoxemia,chest pain,lower breath sound,and lung rale,which were not non-specificity.According to imageological examination,in 17 cases there were 2 cases with pulmonary hypertension (the incidence rate was 11.8%),4 cases with acute lupus pneumonitis (the incidence rate was 23.5%),6 cases with interstitial pneumonia (the incidence rate was 35.3%),7 cases with lesion of pleura (the incidence rate was 41.2%),10 cases with pulmonary infection (the incidence rate was 58.8%).There were no statistical differences between patients with and without lung injury(infectious and non-infectious)in the course,the values of serumn complement,the positive rate of dsDNA and activity index.Lung lesions of the 17 patients recovered quickly after early diagnosis and active treatment.Conclusions Pulmonary manifestation in children with SLE is not uncommon,and it can happen at any stage of the disease,not just on the stage of lupus activity,but it usually indicates disease was not controlled.Pulmonary manifestation of SLE in children involve many parts of lung,including pulmonary parenchyma,interstitial,blood vessels,pleura,etc.Early diagnosis and active treatment can improve the short-term prognosis of lung injury with lupus,and long-term outcome remains to be observed.
10.Military medical literature collection:construction and analysis
Wei LIU ; Jiying HAO ; Li SHENG ; Zhibin YANG ; Songjun WANG
Military Medical Sciences 2014;(10):823-827
Objective To explore the way to compile a global military medical literature collection and perspectives for its research.Methods The names of military medical research institutions and their trends of development were summa-rized via semantic analysis.The collection of retrieval words for military medical research institutions( then the collection) was constructed based on expert consultation.The names of military medical research institutions were collect-ed with manual screening after retrieval withthe collection.The literature collection of military medical research institu-tions was completed with coordinated retrieved of their papers and other publications.Results According to different needs of information analysis, the literature collection of military medical research institutions could be analyzed in terms of their size, types of development, and academic authority.Conclusion Based onthe collection, the military medical research institutions collected in this article included institutions that used to be neglected during the course of information tracking of military medicine.Three kinds of institutions should be paid more attention to.The institutions were the ones with a large number of papers and citations, the ones whose papers increased or decreased dramatically, as well as the ones whose research directions were the priority fields of Chinese PLA.