1.Cardiopulmonary resuscitation in China, 2002 - 2012.
Chinese Medical Journal 2012;125(20):3603-3605
6.Observation of patients' clinical characteristics during recovery period in low flow and circulation closed pattern anesthesia by ZEUS with isoflurane
Kaihua SHENG ; Zhiyi GONG ; Xuehua CHEN
Cancer Research and Clinic 2012;24(8):537-539
Objective To explore the clinical characteristics of patients during recovery period in low flow and circulation closed pattern anesthesia by ZEUS with isoflurane.Methods During elective gynecologic surgery,35 ASA Ⅰ or Ⅱ patients were anesthetized with isoflurane under general anesthesia with tracheal intubation.The ventilation was used with the closed circuit breathing mode (Autocontrol) of ZEUS anesthesia machine.The time of inhale drug,exhale drug and eyes-opend,consumption of drug and complication were recorded during the process.The values of NT stage (NTS),NT index (NTI),the final endexpiratory concentration of isoflurane (EXP),MAC and hemodynamic parameters were recorded during the time of isoflurane stopping inhale,recovery of spontaneous respiration,eyes opening.Results The values of NTI (50±7,74±12,86±10,t =-9.382,t =-16.682,P < 0.01),the EXP [(0.9±0.0)%,(0.1±0.1)%,0,z =-7.262,z =-7.835],MAC [(1.2±0.1)%,(0.2±0.2)%,0,z =-7.186,z =-7.728,P < 0.01] and hemodynamic parameters (SBP,DBP,MAP,HR) [(108.1±13.4) mm Hg (1 mm Hg =0.133 kPa),(66.3±12.1) mm Hg,(84.3± 12.5) mm Hg,(69.8±12.5) /min and (124.6±17.9) mm Hg,(75.7±14.5) mm Hg,(96.0±14.6) mm Hg,(82.8±15.0)/min and (128.0±16.3) mm Hg,(77.1±15.0) mm Hg,(99.8±15.3) mm Hg,(85.2±18.5) bpm] (t =-4.365,t =-2.951,t =-3.574,t =-3.921; t =-5.554,t =-3.309,t =-4.642,t =-4.085,P <0.01) during the time of recovery of spontaneous respiration and tracheal extubation were statistically significant compared to the time of isoflurane stopping (P< 0.01).None of patients experienced intraoperative was awareness.Conclusion Isoflurane can be used for closed circuit breathing mode of ZEUS anesthesia machine,but consciousness recovery need a long time.
7.Role of Oxygen Radicals in Acute Lung Injury Induced by Burns Complicated by Cndotoxemia in Rats
Huiqing SHENG ; Xiaoqi GONG ; Yafei ZHANG
Academic Journal of Second Military Medical University 1985;0(05):-
An animal model of acute lung injury was reproduced by intravenous injection of E. coli endotoxin to burned rats. The histological changes of lung were studied using transmission electron microscope. It was found that leukocytes accumulated in the pulmonary capillaries and adhered to endothelia. The WBC count decreased gradually. The level of MDA, lung coefficient and lung water content were increased. The SOD activity was decreased. Pretreatment with SOD could improve the changes mentioned above. This study suggests that oxygen radicals play an important role in acute lung injury induced by burns complicated by endotoxemia.
8.Analysis the Related Factors Associated with Meningioma Peritumoral Edema
Junyang, GONG ; Jiankang, SHENG ; Qizhong, LUO
Journal of Shanghai Jiaotong University(Medical Science) 2000;20(4):331-333
ObjectiveTo study the factors associated with meningioma peritumoral edema.MethodsPeritumoral edema of 18 patients was assessed on a semi - quantitative form from preoperative radiography. All the patients' clinical information( tumor size, tumor envelope damage, brain surface vein compression, pathological type), malignancy of tumor tissue, vascular endothelial growth factor(VEGF), immuno-histo-chemisty stain were studied to find out the correlation with peritumoral edema. Results There was no correlation between tumor size, pathological type and brain vein compression with peritumoral edema。 Tumor envelope damage and VEGF immunoreactivity were strongly associated with peritumoral edema. ConclusionThese data suggest that meningioma peritumoral edema may bea result of tumor cell producing VEGF in combination with tumor envelope damage, which lead to the damage of normal blood brain barrier and the enterance of edema-causing chemical factor.