Objective To evaluate the feasibility, safety and efficacy of ACS MULTI LINK PENTA (PENTA) stent in patients with coronary artery disease.Methods From March to June 2002, thirty PENTA stents were implanted in 28 patients with 30 de novo lesions. For each patient the demographic, interventional and mean 3 month follow up informations were recorded. Results Almost two thirds of patients suffered from hypertension(61%) and half experienced unstable angina (53%). Most target lesions(67%) had unfavorable morphological characteristics (type B2 or C). No stent deployment failure occurred as well as acute or subacute stent thromobis.The major branches compromised after stenting were only in 2 patients. During floow up,no MACE occurred, except reoccurrence of chest pain in 2 patients (7%). Conclusions The PENTA stent appears to be safe and effective in treating coronary artery disease.

Objective To evaluate the therapeutic efficacy of intra aortic balloon supporting in coronary interventions for high risk patients with coronary artery disease(CAD).Methods Sixteen high risk CAD patients accepted percutaneous coronary intervention assisted by intra aortic balloon pumping together with clinical variables, procedural and follow up informations were recorded and evaluated. Results All patients presented with severe left ventricular dysfunction, multi vessel disease and high jeopardy scores. 12 patients acquired complete revascularization. Mean duration of balloon pumping was (31?17) minutes. Aortic diastolic and mean pressures were increased during balloon pumping [diastolic:(69?11)mmHg pre.vs (131?15)mmHg post.; mean:(82?13)mmHg pre.vs (111?7)mmHg post., P

Objective To evaluate coronary flow reserve (CFR) in patients with myocardial bridging.Methods Between September 2000 and January 2003, thirteen patients were detected myocardial bridging(MB) by coronary angiography(MB group). Another 32 patients with normal coronary arteries were served as a control group. Demographic information and CFR were compared between the two groups. Results All patients in MB group were presented with stable angina pectoris, and the systolic and diastolic coronary compressing stenosis were 78%?7% and 15%?5%, respectively. CFR in MB patients was significantly lower compared with the controls(2.0?0.3 vs 3.3?0.6, P

70), hypertension and multi vessel coronary artery disease.Conclusions Selective renal angiography immediately after coronary angiography is feasible and safe, and it exerts great significance of detection of RAS.

Objective To evaluate the long-term effect of coronary stenting in young coronary artery diseased patients (45) undergoing coronary stenting were chosen randomly as the control group. Comparison the general characteristics, coronary angiographies, interventional and follow-up informations between the two groups was undertaken. Results Comparing with the control group, the young group patients presented much more myocardial infarctions (68% vs 35%, P

0.05).Conclusion Early pre-interventional tirofiban therapy for patients with acute STEMI who undergo primary PCI improves patency of infarct-related artery and tissue reperfusion,but its effects on short-term clinical outcomes are similar to routine tirofiban administration in catheter laboratory.

Objective To evaluate the efficacy and safety of percutaneous stent implantation for native aortic coarctation. Methods Five patients with native coarctation of the aorta underwent percutaneous endovascular angioplasty and stenting. Immediate and long-term outcomes were assessed in terms of blood pressure changes, procedure complications, and medications. Results Compared before and after stenting, the pressure gradient associated with the stenotic segment was decreased immediately after stenting [(73?6) mm?Hg vs (8?2) mm?Hg, P

150?mol/L who underwent PTCA and/or coronary stenting were included (renal dysfunction group). Another 25 age and sex matched patients who had normal serum creatinine level and received coronary intervention at the same period were served as a control group. The status of coronary disease, procedural complications and long term prognosis were compared between the two groups. Results The number of patients with multi vessel disease (72% vs 48%, P

Objective To investigate the the expression of soluble Fas (sFas) in the placenta of pregnancy induced hypertension (PIH) patients after perinatal. Methods Expression of sFas were detected by Fluorescent MGB Probe Real-Time PCR in 34 severe PIH patients and 30 healthy pregnant women served as normal controls.Results Expression of placenta sFas in 34 patients were significantly higher than those in normal controls.Conclusion PIH patients' placenta had higher expressiom of sFas; Detection of sFas may be helpful to value PIH degrade and sFas would be become a indicative markers of cell proliferation and apoptosis during the perinatal period.

Objective To investigate the efficacy of interferon alpha (IFNα) plus adefovir dipivoxil (ADV) and tebivudine (LdT) monotherapy for patients with HBeAg positive chronic hepatitis B (CHB) who have poor response to IFNα treatment.Methods A total of 86 HBeAg positive CHB patients admitted to the Sixth People' s Hospital of Shaoxing during February 2010 and April 2013 were enrolled in the study.All the patients received IFNα monotherapy for 24 weeks and had poor responses.The patients were voluntarily divided into three groups:IFNα monotherapy group (n =21),IFNα plus ADV group (n =30) and LdT monotherapy group (n =35).Chi-square test was used to compare ALT normalization rates,rate of HBV DNA load ＜ 500 copies/mL,HBeAg seroconversion and HBsAg seroconversion rates among three groups.Results After 48 weeks of treatment,the ALT normalization rate in IFNα monotherapy group was 52.6％ (10/19),which was lower than those in IFNα plus ADV group (86.7％,26/30) and LdT monotherapy group (84.8％,28/33) (x2 =6.913 and 6.361,P ＜ 0.05).The rate of HBV DNA load ＜500 copies/mL in IFNα monotherapy group was 26.3％ (5/19),which was lower than those in IFNα plus ADV group (60.0％,18/30) and LdT monotherapy group (54.5％,18/33) (x2 =11.33 and 3.895,P ＜0.05).No HBeAg negative conversion or seroconversion was observed in IFNα monotherapy group,but it was observed in 6 (20.0％,6/30) patients in IFNαt plus ADV group and 7 (21.2％,7/33) patients in LdT monotherapy group (x2 =4.330 and 4.657,P ＜ 0.05).No HBsAg seroconversion was observed in three groups.There were no statistical significant differences in ALT normalization rates,rate of HBV DNA load ＜ 500 copies/mL,HBeAg seroconversion and HBsAg seroconversion rates between IFNαt plus ADV group and LdT monotherapy (x2 =0.042,0019 and 0.064,P ＞ 0.05).Conclusion For patients with HBeAg positive CHB who had poor response to IFNα treatment,IFNα plus ADV therapy and LdT monotherapy have the same efficacy in improvement of both liver function and virological response.