1.Magnetic resonance diffusion tensor imaging of cervical cord in healthy children
Acta Anatomica Sinica 2014;(3):364-368
Objective To investigate the development of the cervical cord in children by using diffusion tensor imaging.Methods Ninety healthy children were undergone with diffusion tensor imaging of the cervical cord by using single-shot spin-echo echo planar image sequence.The values of apparent diffusion coefficients (ADC), fractional anisotropy (FA), average length(Ltract) and volume of tracts(Vtract) were measured in the cervical regions.Results The measurements of each group were as follow:ADC value:0.9747 ±0.2777,0.8493 ±0.2236,0.8210 ±0.1432,0.9198 ± 0.1444,0.9048 ±0.1676;FA value:0.4117 ±0.0391,0.4712 ±0.0199,0.4944 ±0.0439,0.5608 ±0.0443,0.6169 ± 0.0551;Ltract:25.61 ±8.63,24.66 ±7.14,27.03 ±7.23,34.93 ±10.99,37.63 ±10.22;Vtract:3.07 ±1.49,3.00 ± 1.52,3.81 ±1.33,5.41 ±2.35,6.64 ±2.84.FA value, Ltract and Vtract showed significance in different age groups , while ADC value was found no difference ( P<0.001) .Post-Hoc test revealed that FA value was significantly different between age group I and Ⅱ.FA value, Ltractand Vtract presented significantly different between group ⅢandⅣ.FA value difference was also found between group Ⅳand V.FA value, Ltract and Vtract were all positively corelative with age (F=1.758, P=0.145 ) .Conclusion Development of the cervical cord shows periodicity with periodic features .Diffusion Tensor Imaging can be used as a tool to observe and evaluate development of the cervical cord in children .
2.Role of SOCS-3 on leptin resistant and obesity
Academic Journal of Second Military Medical University 2001;0(09):-
The new protein suppressors of cytokine signaling(SOCS) as negative regulators of signaling pathways involve in the cellular actions of many cytokines, including leptin. It regulates intracellular signal transduction cascades such as the JAK STAT pathway. SOCS is now evident of leptin resistance and has close relation with obesity. We reviewed the structure and function of SOCS 3 and the mechanism in leptin signaling pathway,providing data for the potential effect of SOCS 3 in the treatment of obesity.
3.Genetic studies of short stature
International Journal of Pediatrics 2015;(4):400-404
Human height is mainly regulated by the hypothalamus-pituitary-growth hormone axis, and also affected by other factors,such as nutrition and physical activity. Genetic factor is thought to be the main fac-tor,and genetic degree is about 80%. At present,genetic analysis in short stature has made great progresses both at home and abroad,and genes related to the height are more than 180. The article reviews some of the major genes related to the short stature,including the genes related to the adenohypophysis development,the genes re-lated to the GHRH-GH-IGF1 axis,as well as other related gene mutations and performance.
5.Expressions of leptin receptor mRNA and neuropeptide Y mRNA in the hypothalamic arcuate nucleus of obese rat induced by high fat diet
Chinese Journal of Endocrinology and Metabolism 1986;0(03):-
The rat model of obesity was induced by high fat diet and in situ hybridization was performed with oligonucleotide probes.The results showed that expressions of leptin receptor mRNA and neuropeptide Y mRNA were significantly increased, suggesting that these increments might be related to leptin resistance.
6.Method and Practice of Operation and Management Improvement in Clinical Department of Public Hospitals
Chongwei XU ; Junxue SHEN ; Liai ZOU
Chinese Health Economics 2013;(10):66-67
There is room for improvement in the clinical department operation of public hospitals. Therefore, through exampling the practice of a public hospital’ s clinical department, to propose the methods in improving the department management.
7.Foreign body in parotid gland: a case report.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(4):273-274
A 44-year-old male complained recurrent swelling and pain in the left pre-auricular mass over 4 years, which aggravated for 4 months. Ultrasonography revealed a mixed mass echo in the left parotid gland. Computed tomography showed an enlarged parotid gland and a 1.5 cm x 0.9 cm low density shadow in the superficial lobe area with strip high-density shadow in the edge. Although the facial nerves of the patient were found adhered to the foreign body during the operation, the foreign body in parotid gland was removed surgically without any injure to them due to facial nerves protection. In conclusion, facial nerves dissection is necessary to avoid the postsurgical facial paralysis in the surgical removal of foreign bodies in parotid gland.
Adult
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Facial Nerve
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Foreign Bodies
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Humans
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Male
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Parotid Gland
8.A case report of a secondary tonsil follicular dendritic sarcoma after non-Hodgkin's lymphoma.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(6):428-429
Follicular dendritic sarcoma is a rare and low-grade malignant soft tissue tumors , often occurs in the lymph nodes, we report a case of tonsil follicular dendritic sarcoma which occured after Non-Hodgkin's lymphoma had be cured. The chief complaint was oropharyngeal foreign body sensation with hemoptysis three years, found in the left neck mass increased with more than 4 months. The left side of the pharyngeal wall thickening and disappearance of parapharyngeal space with the surrounding lymph nodes extremely enlarged and integrated was demonstrated by the contrast-enhanced CT of neck. Finally,the pathological diagnosis was tonsil follicular dendritic sarcoma.
Female
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Humans
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Lymph Nodes
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pathology
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Lymphoma, Non-Hodgkin
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therapy
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Neck
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Oropharyngeal Neoplasms
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diagnostic imaging
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pathology
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Palatine Tonsil
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diagnostic imaging
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pathology
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Radiography
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Sarcoma
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diagnostic imaging
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pathology
9.Clinical Observation on Combined Use of Urapidil Hydrochloride(Lixiding)and Dobutamine in Treatment of Severe Acute Congestive Heart Failure
Xiaopeng JIA ; Lianyu SHEN ; Guoding ZOU
China Pharmacy 2001;0(07):-
OBJECTIVE:To observe the therapeutic effects of Lixiding(LXD)plus dobutamine(DBT)on severe acute congestive heart failure.METHODS:A total of40patients,including25patients with coronary heart disease,10hypertensive cardiopathy and5ectatic myocardiopathy,were enrolled in this study.Before and after combined use of LXD and DBT,the SBP,DBP,HR,CI,PCWP,TPR and LVEF were measured and the data obtained were detected with t test.RESULTS:After use of drugs,the SBP,DBP,HR,PCWP and TPR significantly decreased in comparison with those before medication(P
10.Efficacy and safety of ropivacaine combined with lidocaine in caudal block for pediatric laparoscopic hernia surgery
Shumin JI ; Yanping SHEN ; Wenhang ZOU
Chinese Journal of Biochemical Pharmaceutics 2016;36(11):100-102
Objective To evaluate the anesthetic effect and safety of ropivacaine combined with lidocaine caudal block in the treatment of pediatric laparoscopic hernia surgery.Methods A total of 70 cases with pediatric hernia surgery in Ningbo Women and Children’s Hospital from May 2014 to October 2015 in this study were divided into control group and experimental group with 35 cases in each group.The patients in the both groups were given routine examination, preoperative anesthesia induction, adopted 7 scalp injection needles to prick into the hiatus sacralis,patients in control group were treated by 1% lidocaine hydrochloride injection mixed liquid 1 mL/kg;patients in the experimental group were treated by 0.25%lidocaine hydrochloride injection and 0.25% ropivacaine hydrochloric injection mixed liquid 1 mL/kg; pediatric hernia surgery, intraoperative continuous pumped into propofol injection 4-6 mL/kg and maintain the mask to the oxygen.The visual analog pain scored( VAS) , visual satisfaction scored ( VSS) and adverse reactions were compared at the end of operation, after operation 0 h,0.5 h,1 h,2 h,4 h,8 h and 24 h.Results The sensory and motor block effective time in the experimental group were later than the control group, the sensory and motor block duration time were shorter than the control group (P<0.05).VAS score of the experimental group was significant lower than control group after operation 2 h ( P<0.05 ) . After operation, postoperative 0.5 h, postoperative 1 h, the VSS score of the experimental group was significant lower than control group ( P<0.05 ) .Lower limbs numbness discomfort duration time of the experimental group was significant lower than control group after operation ( P<0.05 ) . Postoperative agitation rate of the experimental group 8.57% was significant lower than the control group 34.29% (P<0.05).The incidence of adverse reactions of experimental group 5.71% was significant lower than the control group 25.71% ( P<0.05 ) .Conclusion Ropivacaine combined with lidocaine caudal block in the treatment of pediatric hernia surgery has the remarkable effect, with high safety.