With worldwide improvements in the regulations of international and domestic clinical trial conductions, the quality of clinical trials and trial data management are receiving a great deal of attention. To ensure the quality of clinical trials, maintain business flexibilities and effectively utilize internal and external resources, the outsourcing model is used in the management of clinical data in operation of pharmaceutical companies. The essential criteria of a successful outsourcing mode in clinical trial are selection of qualified contract research organizations (CRO); establishment of appropriate outsourcing model, and generation of effective quality control systems to ensure the authenticity, integrity and accuracy of the clinical trial data.
Clinical Trials as Topic ; Data Collection ; methods ; Information Storage and Retrieval ; methods ; Outsourced Services ; Quality Control

Objective The application of modern information technology to manage critical values of clinical examination,in order to improve the management level of patients safety and reduce the medical risk.Methods The critical values reminder in medical security alert system is developed and applied,the core module of the system are warning monitor of equipment record and SMS warning monitor of alerting in testing critical value.Results Through the application of system,the information of testing critical values are obtained duly,comprehensively and accurately,the notification time of clinical testing critical values are abbreviated,the notification scopes are spread and achieved the management of critical value at different levels.Conclusion The application of the system can be perfected the management of critical values,ensured patients safety,improved the medical quality and enhanced the management level of hospital,and then the system has become another example of informationization creating value.

Objects:To investigate the current situation of interpersonal communication inpreparatory students in one Xinjiang medical college from the exchanges between students.Methods:Using self-developed questionnaire,a survey was conducted among 200 preparatory students and depth interviews were conducted for typical cases.Results:Preppies showed a strong willing of interpersonal communication.In the process of students' interaction,some features were presented as followings:pure motives but dissimilarity,narrow range of interactions,lack of interaction ability and the single form of social activities.Conclusion:Based on the above current situation of interpersonal communication in preparatory students,it should enhance the language application ability of preparatory stage,change the idea and attach importance to the education of humanistic quality in preparatory education and train preppy's expression and listening art.

With worldwide improvements in the regulations of international and domestic clinical trial conductions, the quality of clinical trials and trial data management are receiving a great deal of attention. To ensure the quality of clinical trials, maintain business flexibilities and effectively utilize internal and external resources, the outsourcing model is used in the management of clinical data in operation of pharmaceutical companies. The essential criteria of a successful outsourcing mode in clinical trial are selection of qualified contract research organizations (CRO); establishment of appropriate outsourcing model, and generation of effective quality control systems to ensure the authenticity, integrity and accuracy of the clinical trial data.

Objective To investigate the cognitive impairment of middle-aged patients with type 2 diabetes mellitus(T2DM). Methods Wechsler adult intelligence scale-Chinese revised edition (WATS-RC) was used as the tool to examine the cognitive function of middle-aged patients with T2DM and the healthy controls in 51 cases. The t-test was used to compare the differences in score between patients and the control group. The patients were divided into two groups with or without cognitive dysfunction. The logistic regression analysis was made for all the variables to confirm risk factors for the cognitive dysfunction in diabetes. Results The WAITS-RC scores of digit-symbol coding test and block design test were much lower(P<0.05) in diabetes versus control group. The other tests showed no significant difference. The cognitive function was negatively correlated with HbA_1>c and HOMA-IR by logistic regression analysis. Conclusions For middle-aged patients with type 2 diabetes, their cognitive functions such as learning ability, analysis and comprehensive capabilities are impaired. The cognitive function is closely related with HbA_1c and HOMA-IR.

A digital customer service platform in hospital wards is equivalent to a platform to provide convenient, value-added and fine bedside services to in-patients as customers (customers admitted into hospitals and those for physical check inclusive).These services are provided via a set-top box and/or TV set installed with corresponding software.This platform supports such services as bills check, food order, non-medical services, VOD, games and entertainment, as well as commercial services from outside the hospital This article introduces the system structure, functionality, as well as the outcome and value of this platform, pointing out that this platform is an innovation of information technology, and that of hospital management and service mode as well

It is inevitable for hospitals to introduce the concept of hospital client relationship management in order to upgrade service quality．The large population and number of visits of patients have been the bottle-neck for hospitals to implement management of hospital client relationship．Digital technologies make it possible for the hospital to utilize the internal clinical data systems inside the hospital and the communication platforms outside the hospital so as to implement functions of instant interaction and collective management such as one-to-one conversation,SMS,voice messages,emails,etc．This paper has addressed the features of hospital client relationship management,the structure and major functions of a digital platform for hospital client relationship management and its implications and conclusions.

Objective To study the effect of lead exposure in different development periods (father BBLL and mother BBLL,MPBLL,UCBLL,IBLL,CBLL) on children behavior problems. Methods From 1996 to 2004,a nine-year epidemiological cohort study was conducted in a place with severe environmental lead pollution, Guichi district of Chizhou city in Anhui province, China. 210 newly-married couples with the intention to pregnancy and living around a lead and zinc smelt factory from Dec,1996 to Dec,1998 until delivery and then their offspring were chosen. 161 children were investigated through the questionnaires and Achenbach child behavior checklist(CBCL)at Nov,2001 and Aug,2004. Meanwhile, 210 couples baseline blood (father BBLL and mother BBLL), 93 mid-pregnancy blood(MPBLL), 98 umbilical cord blood (UCBLL),165 blood of infants(IBLL), 161 blood of children (CBLL) were collected to determined the levels of lead by PE-AA800 atomic absorption spectrophotometer. Results Geometric mean of mother BBLL, father BBLL, children BLL, infants BLL, UCBLL and MPBLL were (62.71?2.18)?g/L,(72.93?2.06)?g/L, (91.93?1.58)?g/L, (130.39?1.88)?g/L, (54.32?2.11)?g/L and (50.93?1.95)?g/L respectively,and the proportion of blood lead level at which were higher than 100 ?g/L were 32.38%, 38.10%, 45.34%, 43.03%, 10.20%, 9.68% respectively. In 161 infants, the incidence of abnormal behavior problems was 16.1%. The scores of delinquent and abruption in boys were significant higher than those in girls, while the scores of depression and social withdrawal in girls were higher than those in boys. The single correlative and the multiple stepwise regression analysis showed that the score of abruption was positively correlated significantly with MPBLL(?=0.162,P

Objective To investigate the accuracy of 64-detector helical CT in assessing stenoses of coronary arteries. Methods 64-detector helical CT angiography was performed in 128 patients with suspected coronary artery disease,and the results were compared with that of invasive coronary angiography. Results Among 128 patients, 1 724 of 1 920 coronary artery segments were assessable (90%). Overall sensitivity for classifying stenoses was 92%, specificity was 94%, positive predictive value was 82%, and negative predictive value was 96%.Conclusion 64-detector helical CT provides a high diagnostic accuracy in assessing coronary artery stenoses.

OBJECTIVE:To introduce the application of modern information technology in the improvement of management level of TCM decocting center. METHODS:The structure and characteristics of TCM decocting center were analyzed by introducing the implementation of TCM decocting center. The value of TCM decocting center and its need of perfection wer summarized. RESULTS:The application of modern information technology improved the management of TCM decocting center. CONCLUSIONS:Digital management of TCM decocting center is worth of spreading and researching.