Objectives To investigate the relations between serum E2,T level and vascular dementia (VD) and therapy effect of Chinese medicine.Methods Seventy patients were selected and randomly divided into two groups:experimental group,which was treated with Chinese medicine and control group with western medicine.Results There was marked difference in E2 of female patient and E2,E2/T and T of male patient between experimental group and control group (P

FDP/FIP (88.8%), respectively; (3) The diagnostic positivity of combination assay was 80.0% in low or negative AFP producing HCC, while 95.7% in those with elevated AFP. Our data suggested that the combination assay of serum tumor enzyme markers was valuable in the diagnosis of HCC, especially in low or negative AFP HCC patients

The widespread application of adjuvant therapy has shown clear benefits in the treatment of operable breast cancer. It is essential for the clinicians to select appropriate adjuvant regimens for this heterogeneous group of patients. Recent data from clinical trials evaluating the utility of adjuvant therapy were reviewed.

Building a digitized and customer-oriented hospital customer service system is conducive to better service at the hospital.Such a system is an open customer service and management system,comprising digitized customer relation management and service platform,digital intelligent IVR customer service system,video interaction service system for hospital wards,IOT-based health management and service system,and 3G-based seamless pre-hospital and post-hospital green emergency rescue system,as well as other customer service systems including the outpatient auto-calling,self-service,information release,payment management,and IOT-based customer management system.By means of thorough customer analysis,automatic service trigger-off mechanism and considerate customer service,digitized hospital customer service system realized value of the hospital while providing the customers with valuable services.

Objective To investigate the expression of serum vascular endothelial growth factor(VEGF) in patient with bladder transitional cell carcinoma (BTCC) and its relationship with clinicopathological parameters.Methods The clinical data of 68 patients with BTCC who underwent surgical treatment was retrospectively analyzed,the healthy subjects was considered as control group,the serum VEGF levels of patient with BTCC and healthy subjects were detected by ELISA and compared.Results The VEGF levels of bladder cancer group was (317.62 ±89.47) ng/L,and was significantly higher than that of the control group [(53.08 ± 17.40) ng/L] (t =16.017,P ＜0.01).The VEGF levels of invasive cancer group and pathological grading of high-level group were respectively higher than the superficial tumor group and pathological grading of low-level group,compared the difference was significant (t =8.191,6.230,all P ＜0.01).The VEGF level was not significantly difference between the different age groups,gender groups and tumor size groups(t =0.423,0.528,1.307,all P ＞ 0.05).Conclusion The serum VEGF levels are high expression in patients with BTCC,the VEGF levels are closely related to clinical stage and histological grade.The high expression of serum VEGF shows the invasion and progression of BTCC.

Objective To observe the efficacy and safety of Ginkgo biloba extract combined with Nimodipine on patients with acute cerebral infarction.Methods 106 cases of acute cerebral infarction were randomly divided into two groups(control group and treatment group),the control group was given Nimodipine on the basis of regular treatment,and the treatment group was given Ginkgo biloba extract combined with Nimodipine on the basis of regular treatment.Results The total effective rate of treatment group was higher than that of the control group (x2 =3.62,P ＜0.05),improvement of neurological deficit was better than that of the control group (t =2.57,5.32,all P ＜ 0.05),Plasma TC and TG levels were significantly lower than that of the control group(t =4.23,6.43,all P ＜ 0.05).During treatment,patients had no serious adverse reactions.Conclusion Ginkgo biloba extract and Nimodipine have synergistic effects,the two combined treatment of acute cerebral infarction have significantly effects,which is safe and reliable.

Objective To compare the effect of zinc distribution of particles and acetaminophen treats pediatric fever.Methods 108 children with fever were randomly divided into the observation group and the control group,54 cases in each group.The control group was given paracetamol,the observation group was given cloth compound of zinc particles.Efficacy of temperature changes,seizures and the incidence of adverse reaction were compared in two groups.Results The total effective was 96.30％ (52/54) in the observation group,the control group was 81.48％ (44/54),there were no significant differences (x2 =5.86,P ＜ 0.05).The body temperature is remarkably reduced after taking medicine for 0.5h in the observation group (P ＜ 0.05).The body temperature is remarkably reduced after taking medicine for lh in the control group (P ＜ 0.05).The body temperature is remarkably reduced after taking medicine for 0.5,1,2,4 h in the observation group which were lower than those of the control group (P ＜0.05).The incidence of adverse reactions was 12.96％ (7/54) in the control group,which was 11.11％ (6/54) in the observation group,there were no significant differences (P ＞ 0.05).The convulsion rate ioas 3.70％ (2/54) in the observation group,which was 14.81％ (8/54) in the control group,there were no significant differences (P ＜0.05).Conclusion It is faster,longer duration,seizure occurs at a low rate for the cloth compound of zinc particles treats pediatric fever than acetaminophen antipyretic.It is worthy of clinical application.

ObjectiveTo evaluate the efficacy and safety of ibutilide for conversion of paroxysmal and persistent atrial fibrillation.Methods31 patients with atrial fibrillation duration less than 90 days were included into amiodrone or ibutilide group.16 patients were intravenously administer with amiodrone and 15 patients with ibutilide separately.Conversion rate,time needed to converse and adverse effects were compared between two groups.ResultsThe total conversion rate of ibutilide group was significantly higher than that of amiodrone group (66.7％ vs 37.5％,x2 =1.98,P ＜ 0.05 ).Time needed to converse was significantly shortened in ibutilide group compared with amiodrone group [ ( 31.75 ± 7.39 ) min vs ( 51.87 ± 9.26 ) min,t =3.67,P ＜ 0.05 ].No clinical significant adverse effects were observed in ibutilide group.ConclusionIntravenous administration of ibutilide in cardioversion of paroxysmal and persistent atrial fibrillation was more safe and effective than amiodrone.

ObjectiveTo observe the effect of amlodipine besylate combined with benazepril in treatment of old patients with primary hypertension and left ventricular hypertrophy,and analyze the safety.MethodsOne hundred and eight old patients with primary hypertension and left ventricular hypertrophy were divided into observation group(54 cases) and control group(54 cases) by random digits table.The patients in observation group were treated with amlodipine besylate combined with benazepril and the patients in control group were only treated with amlodipine besylate.The levels of blood pressure,interventricular septal thickness(IVST),left ventricular posterior wall (LVPW),left ventricular end-diastolic dimension (LVEDD) and left ventficular mass index(LVMI) before and after treatment for 6 months were measured and compared between two groups.The adverse effects after treatment were compared too.ResultsAfter treatment,the levels of 24hSBP,24hDBP,IVST,LVPW,LVEDD and LVMI were significantly decreased in both groups (P ＜ 0.05).Moreover,the levels of 24hSBP,24hDBP,IVST,LVPW,LVEDD and LVMI after treatment in observation group were significantly lower than those in control group(P ＜ 0.05).There was 1 case ( 1.9％ ) of dry cough,2 cases (3.7％) of mild ankle edema in observation group,while only 2 cases (3.7％) of mild ankle edema in control group.There was no significant difference in adverse effects between two groups (P ＞ 0.05).ConclusionsCompared with amlodipine besylate single treatment,amlodipine besylate combined with benazepril in treatment of old patients with primary hypertension and left ventricular hypertrophy can more effectively control blood pressure and reverse left ventricular hypertrophy.The adverse effects are not increased,which can be applied in clinic.