ObjectiveTo explore the effects of five-tone therapy on preoperative psychological reactions of patients undergoing elective surgery.Methods Totally 120 patients were enrolled in our hospital for elective surgery. They were randomly and equally divided into a control group and an observation group according to the random number table. Patients in the control group was treated with conventional nursing intervention,while patients in the observation group received five-tone surgery on the basis of conventional nursing intervention. Their preoperative anxiety was assessed with Zung′s self-rating anxiety scale(SAS),and their systolic blood pressure (SBP),diastolic blood pressure(DBP) and heart rate(HR) at admission(T1),in postoperative conversation(T2),in the morning on the day of surgery(T3) and 15 minutes after the surgery(T4) were monitored.Results After the intervention,the SAS scores at T2 and T3 of the patients in the observation were(42.2±10.5) and(43.2±10.8), respectively,lower than those of the patients in the control group(t=2.118,2.801;P<0.05). The SBP,DBP and HR at T4 of the patients in the observation group were(122.3±12.5) mmHg,(74.1±8.9) mmHg,and(72.5±7.1) times/min,respectively,which were significantly lower than those of the patients in the control group(t=2.695,2.440, 4.40;P<0.05).Conclusions Five-tone therapy can effectively alleviate the preoperative psychological reactions of patients undergoing elective surgery and stabilize their vital signs.