1.Curative efficacy of Yixin Bardiranjibuya Keli in treatment of somatoform disorders
Chinese Journal of Biochemical Pharmaceutics 2017;37(4):75-77
Objective To evaluate the clinical efficacy of Yixin Bardiranjibuya Keli combined with escitalopram in the treatment of somatoform disorders.Methods 90 patients with somatoform disorders from March 2014 to March 2015,were recruited in our hospital as the subjects of this study.According to the random number method,the observation group and the control group were divided into observation group(45 cases)and control group(45 cases).The control group was treated with escitalopram,and the observation group was treated with Yixin Bardiranjibuya Keli on the basis of the control group.(SCL-90),Hamilton Depression Rating Scale(HAMD),Hamilton Anxiety Scale(HAMA),Health Status Questionnaire(SF-36PCS),Mental Health Overall Evaluation(SF-36PCS)before and after treatment,MCS score,adverse reaction,and curative effect.Results After treatment,the scores of SCL-90,HAMD and HAMA in the observation group were significantly lower than those in the control group [(2.40±0.53)vs.(2.47±0.56),(7.32±1.08)vs.(13.69±2.81),(4.82±1.21)vs.(9.93±2.02)],respectively(P<0.05),and the scores of SF-36PCS and MCS were significantly higher than those of the control group(P<0.05).The total effective rate was 95.55(48.38±11.02)points(P<0.05),and the adverse reactions were significantly lower than those in the control group [8.88%(4/45)vs 24.44%(11/45)%,Significantly higher than the control group 73.33%(P<0.05).Conclusion Yixin Bardiranjibuya Keli combined with escitalopram for the treatment of somatosensory disorder is significant and effective in relieving anxiety and depression of the patients and improving the physical symptoms of the patients,which can be used as the first choice of treatment.
2.Diffusion and distribution of imported Oncomelania snails in non-endemic areas of schistosomiasis
Zhishan ZHOU ; Shaoyu HUANG ; Chusheng LI ; Rongxing LIN ; Qiming ZHANG
Chinese Journal of Schistosomiasis Control 2010;22(1):69-71
Objecitve To observe the diffusion and distribution of imported Oncomdania snails in non-endemic areas of schistosomiasis.so as to provide scientific basis for developing the scheme of snail surveillance.Methods Oncomelania snails from the msrshland of Dongting Lake were imported in a waste land in March,2008,Qingxin County,which belonged to non-endemic areas of schistosomiasis.and their diffusion and distribution condition were observed from May to December in the same year.Resuits A total of 1 600 Oncomelania snails were imported.The occurrence rate of frame with snails in sunny days and cloudy rainy days were22.88%and 29.24%,respectively,and there was a statistically significant difference between them(χ~2=4.113,P=0.043).Those in waste Land and the sides/bottoms of the ditches were 9.38%and 35.99%,respectively,and the difference between them also showed a statistical significance(χ~2=67.246,P<0.001).The average density of living snails in sunny days and cloudy rainy days were 0.79 and 1.11 No./0.1 m~2,respectively,and those in waste land and the sides/bottoms of the ditches were0.11 and 1.34 No./0.1 m~2.The furthest diffusion distance of snailswas 4.5 m.Conclusions The detective opportunity of imported snails is relatively high in cloudy rainy days,which mainly distribute at the sides/bottoms of ditches and diffuse along the ditches.
3.Reforming and implementation of culturing program for nursing undergraduates with internationalized vision
Zhifen LI ; Jianrong ZHOU ; Chen XU ; Long YUAN ; Shaoyu MU
Chinese Journal of Medical Education Research 2011;10(11):1302-1304
With the internationalization of nursing education,one major project facing higher nursing education is to foster lots of high quality nursing specialists,with properties of international vision,development prospect,and adaptation to international nursing positions.Chongqing Medical University engaged in reforming and implementation of talents culturing and yielded significant effect along with the main competency ideology of humanistic caring,critical thinking,evidence-based nursing,practicing and international competition.
4.Peripheral blood stem cell transplantation for treating nervous system disease: Possibility, feasibility, and confidence
Shaoyu ZHOU ; Chengwen ZHANG ; Bijia TANG ; Xianzhi ZENG
Chinese Journal of Tissue Engineering Research 2010;14(1):142-146
BACKGROUND: Peripheral blood stem cells (PBSCs) can be enhanced and differentiates into all kinds of neural cells and produce several kinds of neural growth factors in vitro, and have been used to treat several kinds of neural diseases and they showed satisfactory outcomes. It is now a research focus to optimize the culture conditions to induce the stem cell to differentiate into neural cells. On the other hand, it also becomes a focus of its amplification and differentiation. OBJECTIVE: To make a review on researches on treating brain lesion, genetic defection or degenerating diseases using PBSCs during recent years.METHODS: Researching Pubmed database(1999-01/2009-09), using "peripheral blood stem cell, neural, repair" as research words and these Chinese words in CNKI database(1999-01/2009-09). RESULTS AND CONCLUSION: 221 articles were collected altogether including 41 Chinese articles and 180 English articles. Totally 27 articles were adapted altogether after rejecting published early, repeat and similar articles. PBSCs can be enhanced and differentiates into all kinds of neural cells in vitro, and delivered into central neural system and improve the function of lesion neural area. It is not fully understood the differentiation mechanism of peripheral blood stem cells, but numerous studies have shown that surface marker antigen of peripheral blood stem cells is closely associated with its biological characteristics. There are many studies addressing surface marker of peripheral blood stem cells, but researchers cannot identify a reliable marker that can directly label peripheral blood stem cells. Function of CD34 remains unclear, so the principle of CD34 as a marker of hematopoietic stem cells receives challenge. It is necessary to do further researches on issues on how to enhance survival rate of PBSCs in vivo and the tendency to differentiate into neural cells.
5.Discussions on patients' safety education in the nursing undergraduate education
Wenfen ZHU ; Bing YANG ; Hengyu ZHOU ; Jianrong ZHOU ; Shaoyu MU ; Zhifen LI
Chinese Journal of Medical Education Research 2013;(9):940-942
Patients' safety is a hot topic of hospital management all over the word. Strengthening the patients' safety education for medical students and nursing students is an effective measure to protect patients' safety. In nursing school of Chongqing Medical University,patients' safety education was con-ducted through the course of undergraduate education. Contents of patients' safety education were com-bined with the professional courses,which are taught step by step in the professional course learning phase for different grades. Patients' safety education took a lot of teaching forms to cultivate the students' patient safety consciousness and preliminary results were achieved.
6.Investigation into the advanced training status for emergency department nurses in Chongqing
Shaoyu MU ; Fuying LI ; Yanhan CHEN ; Manping GU ; Zhifen LI ; Jianrong ZHOU
Chinese Journal of Medical Education Research 2012;11(3):243-245
ObjectiveTo study the advanced training status for emergency department nurses in Chongqing,and to improve the training program.MethodsThe basic and professional information of 208 emergency department nurses who obtained advanced training for emergency nursing in the previous 5 years was analyzed and the self-designed Satisfaction Survey on Teaching and Self-evaluation on Training Outcome were applied to learn about the feedback of trainees.ResultsThe average age of trainees was ( 29.24 ± 5.44 ),among whom 65.86% with junior college education experience,49.51% with 2-5 years of working experience,50.48% at primary professional rank,61.53% from second level hospitals.Their average score ( 77.91 ± 7.69 ),and teaching satisfaction score was ( 87.01 ± 7.63 ).The survey indicated that self-evaluation on training outcome was significant to enhance emergency nursing knowledge and skills,while weak to improve research and managing capability.ConclusionNurses attending advanced training for emergency nursing are characterized with short working time,low professional ranks,jagged education experiences and various levels of hospital. It is suggested to adopt leveled training in accordance with education experience and working hospital of trainees,and to strengthen nursing research and team managing competencies.
7.Study on feedback of operating room specialty certified nurse theoretical training and quality improvement
Yuerong LI ; Fengqiong YI ; Qinghua ZHAO ; Jianrong ZHOU ; Shaoyu MOU ; Zhifen LI ; Hongyan CHEN
Chinese Journal of Medical Education Research 2015;(1):94-98
Objective To explore curriculum and faculty qualification of Chongqing operating room (OR) specialty certified nurse theoretical tralning program by feedback of students, and to im-prove the quality of tralning. Method Relying on the national key project of the First Affiliated Hos-pital of Chongqing Medical University, Chongqing Health administration OR nurse specialist tralning program set additional courses related to research, teaching, patient safety and first ald tralning based on operation room specialist nurse tralning outline. 81 participants were given questionnalres issued by college of nursing after the 7th OR specialist nurse theoretical tralning, and statistics analysis was made of it. Result Effective questionnalres was100%. The overall judgment on theory tralning was high, with 92.60%of the students giving overall score above 150 points (out of 170);93.84%of students sat-isfied on teaching staff ratio while 95.06% students satisfied on course content. For the 17 items, the majority scores given by the students were ≥ 9 points (a 10-points scale), on the top of the list were item “Theoretical tralning helps to enhance professional theoretical level and guide clinical practice”“Teaching content meet needs of OR specialist nurses” “Teaching content is helpful to improve the core competence of specialist nurses” (all 96.30%, 78 out of 81), while the bottom was “Instructor create an environment which fosters student participation”(85.19%, 69 out of 81). Conclusion Chong-qing OR specialist theoretical tralning has good practical and guidance property, the content meet OR nurses needs, instructor ratio is reasonable, and students are highly satisfied with it. Instructors need to encourage students' participation in class interaction, and pay attention to improving their research capabilities.
8.Percutaneous Insertion of the Inferior Vena Cava Filter
Ruming ZHOU ; Minhua LIU ; Shuibo QIU ; Jiaying ZHU ; Shaoyu ZHUANG ; Huijun YANG
Journal of Practical Radiology 2000;0(02):-
Objective To evaluate the clinical indicat ion and effect of inferior vena cava filter. Methods 17 cases of deep venous thrombosis were treated w ith insertion of the inferior vena cava filter. In 4 cases the thrombosis were d rawn by Hydrolyser catheter with popliteal vein punction, in another the thrombo sis were analysed by Urokinase with vena dorsalis pedis injection.Results The filters were successfully inserted. No seious complication were observed. The thrombosis were discharged in 2 cases with Hydr olyser catheter ,and in 4 cases with Urokinase analyse. No pulmonary thromboembo lism was observed.Conclusion The inferior vena cava filter insertion is a e ffective method to provent pulmonary thromboembolism, and a safe step for the in tervenional therapy to the deep venous thrombosis.
9.Quantitative Assessment of Brain Damage in Acute Phase Carbon Monoxide Poisoning Using Intravoxel Incoherent Motion Imaging
Yanli ZHANG ; Tianhong WANG ; Xiaoxue TIAN ; Chaoning ZHOU ; Zhaodong LIU ; Shaoyu WANG ; Junqiang LEI
Chinese Journal of Medical Imaging 2017;25(3):185-189,195
Purpose To quantitatively evaluate the severity of brain damage in the acute phase of CO poisoning using intravoxel incoherent motion imaging.Materials and Methods MRI scans were performed in 26 patients with CO intoxication of acute stage and 18 healthy controls with matched age and gender.The difference of D value,D* value and f value in different ROIs between the poisoning and the control groups were compared,and the best cut-off values were determined.The correlation between the consciousness state and the D value as well as f value in the vulnerable area of the brain (globus pallidus) was analyzed.Results Compared with control group,the D and F value of the poisoning group were decreased in multiple ROIs,of which statistical significance was observed in the f values in the centrum semiovale,globus pallidus and thalamus,and the D values in the centrum semiovale,lateral ventricle,globus pallidus and corpus callosum splenium (P<0.05).The best cut-off value,sensitivity and specificity were as follows:fcs=51%,77%,73%;fga=61%,77%,83%;ft=80%,85%,64%;D,=0.69×10-3 mm2/s,85%,83%;Dlv=0.65× 10-3 mm2/s,73%,89%;Dga=0.68× 10-3 mm2/s,62%,83%;Dccs=0.70× 10-3mm2/s,81%,89%.The disturbance of consciousness was positively correlated with decrease of D value and f value (rD=0.828,rf=0.745,P<0.05).Conclusion The D and f values of intravoxel incoherent motion imaging can quantitatively evaluate the brain damage severity in acute CO poisoning.
10.Nodular lesion on the tonsil
Lijuan HU ; Ping WEI ; Wei LIU ; Shaoyu CHEN ; Xiaoge ZHOU
Chinese Journal of Pathology 2019;48(1):48-50