Surazepam ( Sur ) is a benzodiazepine derivative. Sur ( 0.2~0.27m-mol/L ) inhibited the contraction of isolated cervices uteri of rats and human beings induced by oxytocin and Ca2+ after high K+ concentration depolarization Sur ( 3.5~ 4 mg/kg ) iv could also inhibit the spontaneous contraction of uterus of rabbit in situ. The cumulative dose-response curves for Sur and CaCl2 exhibited non-competition.Both Sur and nifedipine markedly inhibited extracellular and intra-cellular Ca2+ dependent contraction induced by oxytocin.

Methoxyadiantifoline 10 mg/kg i.v. significantly increased the arrhythmia- inducing dose of aconitine in anaesthetized rats, and that of ouabain in anaesthetized guinea pigs. It markedly prevented ventr icular fibrillation induced by chloroform. Methoxyadiantifoline is also effective in preventing reperfusion-induced arrhythmias in anaesthetized rats. It was demonstrated that methoxyadiantifoline slowed heart rate significantly, and prolonged P-R and Q-Tc interval of ECG in rats.

Objective To study the method and ability of multi-slice CT isotropic scan and post-processing in displaying the anatomy of cervical vertebrae.Methods The normal cervical spines in 53 cases were scanned with isotropic parameters using 16-slice-helical CT.All the images were post-processed with the methods of MPR,MIP,SSD and VRT and each other were compared between them,then the best one was selected to compare with axial CT images and plain films.The abilities in displaying inter-vertebrae disc,spinal canal longtitude,vertebrae body,vertebral arch,zygapophyseal joint and inter-vertebrae foramen were compared among the 3D reconstruction,direct CT scan and X-ray plain film including post-anterior,lateral,left-anterior oblique and right-anterior position project.Results The quality of isotropic post-processing images had no remarkable differences with that of direct CT scan in showing inter-vertebrae disc,but it was better than X-ray plain film and conventional CT scan mode in showing other structures.Conclusion The multi-slice helical isotropic CT scan and post-processing images are of great value in the study of cervical spine.