1.Discussion on mobile vehicle assembling project for radiation medical examination
Chinese Medical Equipment Journal 2004;0(09):-
The mobile vehicle for radiation medical examination is a necessary equipment out of the hospital.Because there's no canonical standard,every hospital designs and assembles it according to self requirements.Dust pulmonary disease is the most serious disease with the highest incidence in occupational diseases and the high-KV X-ray shoot is an indispensable medical examination for it.This paper makes a series of research for better assembly of high-KV X-ray shoot apparatus,normal X-ray machines and giant mobile vehicles.
2.Discussion on purchase rectification and improvement in hospital equipment department after special treatment
Chinese Medical Equipment Journal 2004;0(08):-
Anti-commercial bribery in medicine and medical appliances trade is the main work of national special treatment in 2006.This paper discusses the improving methods to establish a long-term mechanism to promote fair competition and resist illegal transactions in purchasing medical equipments or materials.
3.Experiences of How to Manage Equipment Maintenance
Chinese Medical Equipment Journal 2009;30(7):90-91
Medical equipment maintenance management as an important part of hospital management has always been a difficulty, particularly in small and medium-sized hospital. Because of their weak technical force and the growing diversity, complexity, high-tech modern medical equipment, methods for scientific and effective management are more important. The experiences of how to manage equipment maintenance are introduced.
4.Interleukin-1 beta gene polymorphisms and variation in whole genomic expression profiles of chronic atrophic gastritis
Shaoying WANG ; Xiaoying SHEN ; Caiyun WU ; Feng PAN ; Yuanyuan SHEN ; Haihui SHENG ; Ximei CHEN ; Hengjun GAO
Chinese Journal of Digestion 2009;29(5):326-330
Objective To investigate the whole genomic expression profiles of chronic atrophic gastritis with interleukin(IL)-1β-31CC/-511TT genotype as measured by oligonucleotide microarray technique.Methods Genomic RNA was extracted from gastric biopsies of 12 patients with chronic atrophic gastritis(6 with IL-1β-31CC/-511TT and 6 with IL-1β-31TT/-511CC).The genomic profiles of IL-1β gene polymorphisms 31CC/-511TT and 31TT/-511CC were compared and tested for differential expressed genes associated with 31CC/-511TT using Agilent human whole genomic oligonucleotide microarrays.The results were further analyzed in terms of gene ontology(GO).Results There were 200 differentially expressed genes associated with IL-1β-31CC/-511TT,159 of which were up-regulated and 41 were down-regulated.These genes mainly involved in macromolecule metabolic process,post-translational protein modification,ubiquitin cycle,and protein kinase cascade.Five genes had biological activities,one of which was down-regulated gene(PCSK5)and 4 were upregulated genes(PRKCA,NPLOC4,TRIB3 and MAPKAPK3).Conclusions The chronic atrophic gastritis with IL-1β-31CC/-511TT genotype has molecular phenotypes which is associated with malignance and inflammation.These individuals are needed more intensive preemptive treatment and dynamic surveillance.
5.Expression and significance of Gab2 in colorectal cancer tissues
Chenbo DING ; Jihong FENG ; Weina YU ; Shaoying GAO ; Lin XU ; Chao CHEN ; Junmin LUO
Chinese Journal of Immunology 2015;(2):160-162,168
Objective:To investigate the expression and significance of Gab 2 in colorectal cancer tissues .Methods:Immuno-histochemistry was used to detect the expression of Gab 2 in 78 cases of colorectal cancer tissues and 46 cases of the adjacent tissues and to analyze the association of Gab2 expression with the clinicopathologic features of colorectal cancer;The expression of Gab2 in samples from 10 cases of colorectal cancer tissues and matched adjacent nontumorous tissues was detected by Western blot .Results: The results of immunohistochemistry demonstrated that the Gab 2 protein positive expression rate in 78 cases of colorectal cancer was 53.85%;whereas was negative expression or weak in the adjacent tissues , showing a significant difference of comparison within this result (P<0.001) .The expression of Gab2 in colorectal cancer was related with TNM stage and lymph node metastasis (P<0.05) , but no relation with the size and differentiation of tumor (P>0.05) .Western blot showed that the Gab2 protein expression of colorectal cancer cases was significantly higher than that of matched adjacent nontumorous tissues ( P<0.05 ).Conclusion: Gab2 was overexpressed in colorectal cancer .Gab2 maybe play an important role in carcinogenesis and progression of colorectal carcinoma .
6.Effects of CTGF on the periodontal tissue remolding during orthodontic tooth movement
Jiangtian HU ; Song LI ; Guojie GAO ; Bing YU ; Shaoying SHEN ; Yali LIU
Journal of Practical Stomatology 2010;26(1):24-28
Objective: To study the effects of CTGF on the periodontal tissue remolding during orthodontic tooth movement. Methods: A mouse model of orthodontic tooth movement was established. The CTGF and NS were injected into the periodontal tissue of the first molar. HE staining, immunohistochemical staining and automatic image analysis system were used to detect the changes of periodontal tissue and the expression of VEGF. Results: The periodontal tissue remolding accompanied the over expression of VEGF during the orthodontic tooth movement. At day 7, the remolding was most active and the expression of VEGF was the highest. CTGF injection induced acceleration of periodontal remolding and up-regulating the expression of VEGF during orthodontic tooth movement, especially at day 7 and day 15 after the orthodontic force were applied. Conclusion: In the mouse model of orthodontic tooth movement, periodontal CTGF injection induces over expression of VEGF and accelerates the periodontal remodeling during orthodontic tooth movement.
7.Tsallis entropy-based prior for PET reconstruction.
Yuanyuan GAO ; Lijun LU ; Jianhua MA ; Zhaoying BIAN ; Qingwen LU ; Lei CAO ; Shaoying GAO
Journal of Biomedical Engineering 2013;30(3):455-459
Maximum a Posteriori (MAP) method has been widely applied to the ill-posed problem of image reconstruction. The choice of prior is the crucial point on MAP methods. However, the most conventional priors will lead to a blurring of the whole image or cause ladder-like artifacts. We therefore proposed a Tsallis entropy-based prior for positron emission tomography (PET) iterative reconstruction in MAP framework. The method uses a Tsallis entropy-based prior to eliminate the uncertainty between prior information and the estimated images. We tested this method in the phantom image, compared it with the traditional prior methods. the results showed that the proposed algorithm could suppress noise and obtain better reconstructed image quality.
Algorithms
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Artifacts
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Entropy
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Image Processing, Computer-Assisted
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methods
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Phantoms, Imaging
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Positron-Emission Tomography
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methods
8.Clinical distribution and drug resistance of 179 isolates of Streptococcus agalactia
Yulan LIN ; Shoutao CHEN ; Zhen XUN ; Zejia ZHANG ; Xiangyu YAN ; Shaoying GUO ; Yufen LIU ; Liqin GAO ; Longjie GAN ; Er HUANG ; Qishui OU ; Bin YANG
International Journal of Laboratory Medicine 2015;(10):1376-1378
Objective To investigated the clinical distributions and antimicrobial susceptibility of Streptococcus agalactia strains isolated from the patients .Methods The identification and susceptibility of the strains were mainly measured by automatic VITEK‐Ⅱ system ,the K‐B disc diffusion tests were used for the resistance test of erythromycin ,meropenem ,and D‐test .Results The iso‐lates were mainly from urine (63 .1% ) ,genital tract(7 .8% ) and wound secretion(6 .7% ) .They were obtained from patients in dif‐ferent situations ,including 110 patients who were older than 50 years old (61 .5% ) ,113 female patients (63 .1% ) ,12 gravidas (6 .7% ) ,3 vertical transmitted newborns(1 .7% ) ,and 82 patients with cancer ,undergoing chemo radiotherapy ,with diabetes ,tuber‐culosis or after operations(45 .8% ) .The resistant rates of the isolated Streptococcus agalactia to erythromycin and clindamycin were 42 .9% -93 .3% and 41 .9% -80 .0% respectively .The positive rate of D‐test was 4 .1% .The strains were highly resistant to tet‐racycline(>80% ) ,while the resistance to penicillin was below 10% except in 2008 .All isolates were susceptible to vancomycin and meropenem .Only one strain was resistant to Quinupristin‐dalfopristin .Conclusion Streptococcus agalactia infection in adults most‐ly cause genitourinary tract ,skin and soft tissue infections .There were more females than males with Streptococcus agalactia infec‐tion .Penicillin andβ‐lactams are still the first choice for the treatment .Erythromycin ,clindamycin and tetracycline should be used with caution under the guidance of laboratory susceptibility test results .
9.Observation of clinical effects of acupoint injection in the treatment of pelvic pain induced by pelvic floor myofascitis
Shaoying YAN ; Zhifang DUAN ; Wei ZHU ; Yanru YIN ; Xuejuan GAO ; Yueqin YU
China Modern Doctor 2015;(15):51-53,56
Objective To explore the clinical effects of transvaginal acupoint injection in the treatment of chronic pelvic pain induced by pelvic floor myofascitis. Methods All 80 patients with pelvic floor myofascitis were randomly assigned to an observation group and a control group, with 40 patients in each group. The observation group was given the treatment of transvaginal pain spot injection, and the control group was given transvaginal non-pain spot injection. Changes of clinical symptoms, signs, pain scores and other indices before the treatment, 1 week and 2 weeks after the treatment between the two groups of patients were observed and compared. Results Comparison of pain scores between the treatment group and the control group before the treatment was not significantly different (P>0.05); pain scores after the treatment in the two groups were significantly lower compared to those before the treatment, and the differences in the two groups were both significant (P<0.01). The curative effects in the treatment group were better than those in the control group (P<0.01). Conclusion Transvaginal acupoint injection is able to significantly alleviate chronic pelvic pain induced by pelvic floor myofascitis, but accurate pain spot injection is required.