1.Investigation into long-term effect of extra-trabeculotomy on congenital glaucoma
Chinese Journal of Experimental Ophthalmology 2001;19(1):70-71
ObjectiveTo evaluate the long term effect of extra-trabeculotomy on congenital glaucoma.MethodsThe curative effect in 49 eyes of 29 cases with congenital glaucoma,which underwent extra-trabeculotomy in the same hospital in the last 25 years,were retrospectively studied.The average time of post-operation was 92 months.The intraocular pressure and corneal diameter were recorded.ResultsThe final intraocular pressure in 45 of 49 eyes (91.84%)was less than 21 mmHg.The mean postoperative IOP was (16.84±4.11) mmHg.No serious complications occurred.Conclusion This study showed that treating congenital glaucoma by extra-trabeculotomy can control its progresson and attain a long-term satisfactory effectiveness.
2.The effect of triamcinolone acetonide by single intravitreous injection or repeatedly sub-Tenoninfusion on relieving diabetic macular oedema
Hongling LIU ; Guangzhong FENG ; Jianju LIU ; Hao CUI ; Shaoying FU
Ophthalmology in China 2009;18(4):246-250
Objective To study the efficacy of intravitreous injection (IVI) or sub-Tenaninfusion (STi) of triamcinolone acetonide (TA) for diabetic macular oedema. Design Retrospective cases series. Participants 37 cases (37 eyes) with diabetic macular oedema confirmed by fundus fluorescence angiography (FFA) and optical coherence tomography (OCT). Methods Patients were received 4mg TA by single intravitreous injection or 40mg TA by three times sub-Tenoninfusion at 0d, 2w, 4w. The best corrected visual acuity, fundus examination, intraocular pressure, fundus fluorescence angiography were further analyzed, and the retinal thickness of macular fovea were measured by OCT. Main Outcome Measures The visual acuity, thickness of retinal macular fovea, ocular pressure was measured. Results 32 cases (32 eyes) completed the 24 week followed-up. In group IVI, the visual acuity before and after injection was 0.10±0. 03, 0.24±0.06(F=15.459, P=0.000) respectively; and retinal thickness of macular fovea is(460.73±46.33)μm,(394.53±41.43)μm (F=25. 282, P=0.0000) respectively. But in group STi, the visual acuity before and after injection is 0.11±0.04, 0.18±0.07(F=6.989, P=0.000) accordingly; and retinal thickness of maculur fovea is (454.76±56.28)μm,(424.94±42.69)μm (F=5.145, P=0.000) respectively. There was obvious statistical significance between two methods at same time point(all P<0.05). The serious, irreversible complications had not been found in all patients during follow-up. Conclusion Triamcinolone acetonide by single intravitreous injection or repeatedly sub-Tenoninfasion are good ways to relieve diabetic macular oederna, IVA-TA is more effective, and STi-TA safer. (Ophthaimol CHN, 2009, 18: 246-250)
3.Microvascular decompression in treating cranial nerve diseases
Zhiqiang ZHANG ; Tao HUANG ; Xiaochuan LUO ; Caijun XIE ; Shaoying XIE ; Youbi SHEN ; Lisen SUI ; Fu HAN
Clinical Medicine of China 2008;24(9):926-928
Objective To study the efficacy of microvascular decompression in treating cranial nerve diseases. Methods 156 patients were treated with microvaseular decompression,of whom 119 were with trigeminal neuralgia,34 with hemifacial spasm and three with glossopharyngeal neuralgia.Rusults The overall effective rate was 96.8%(151/156) and the corresponding effective rate for the above three conditions were 94.2%,97.1% and 66.7%. Conlusions Mierovaseular decompression iS an effective treatment for cranial nerve diseases.
4.Data mining of Yuan-Shaoying's experience on chronic prostatitis based on UPOINT phenotype system
Xujun YOU ; Wei FU ; Qing ZHANG ; Shaoying YUAN
International Journal of Traditional Chinese Medicine 2020;42(8):787-792
Objective:To discusses the medication rules of Professor Yuan-Shaoying in the treatment of chronic prostatitis (CP), and to explore the relationship between TCM Syndrome Types and UPOINT system classification. Methods:The TCM syndrome type frequency, UPOINT system classification frequency, drug frequency, four Qi and five flavor meridian tropism frequency were counted by using TCM inheritance auxiliary platform (v2.5). The TCM Syndrome Types and TCM of each type in UPOINT system were obtained according to complex system entropy clustering.Results:A total of 123 prescriptions were included, involving 9 TCM syndrome types, of which the top five were dampness heat stasis syndrome, qi stagnation and blood stasis syndrome, kidney deficiency and blood stasis syndrome, dampness heat downpour syndrome, liver depression and kidney deficiency syndrome. The majority of patients with damp heat stasis syndrome were U-type (urination symptoms) and I-type (infection symptoms), liver depression and kidney deficiency syndrome were mainly p-type (psychological symptoms) and N-type (neural symptoms), most of qi stagnation and blood stasis syndrome were O-type (organ-specific symptoms) and T-type (pelvic floor muscle pain). There were 123 kinds of herbs, and the top five are Shixiaosan ( Wulingzhi + Puhuang), Yanhusuo, licorice, wild grape root and Salvia miltiorrhiza. The drugs mainly include promoting blood circulation and removing blood stasis, clearing heat and tonifying deficiency. The channels of meridian are mainly liver, spleen and kidney. Cold and flat properties are common, while bitter, sweet and pungent are common. According to the U-type classification, the Chinese medicines for clearing heat and detoxification, promoting blood circulation and removing blood stasis were the main drugs, and the top three Chinese medicines were wild grape root, snake berry and licorice root; the P-type was mainly composed of soothing the liver and relieving depression, promoting blood circulation and tonifying the kidney; the top three used frequency were bupleurum, licorice and Paeonia Alba; the O-type was mainly used for promoting Qi, promoting blood circulation, dredging collaterals and relieving pain, and the top three were used frequently. According to the I-type, the main TCMs were clearing heat and activating blood circulation, removing dampness and removing dampness. The top three kinds of TCM were wild grape root, Shixiaosan and liquorice. The N-type was mainly composed of soothing the liver and dredging collaterals, promoting blood circulation and tonifying the kidney, and the top three were bupleurum, Sparganium and Salvia miltiorrhiza; the T-type was mainly the TCM of promoting blood circulation and relieving pain, tonifying liver and kidney; and Yanhusuo, Shixiaosan and Salvia miltiorrhiza were the top three Chinese medicines used frequently. Conclusions:Professor Yuan-Shaoying often takes "promoting Qi, activating blood circulation and removing blood stasis "as the main treatment principle of CP, focusing on regulating the three meridians of liver,spleen and kidney. The relationship between UPOINT system and TCM syndrome types were warranted in further.