[Abstraet] Alteplase intravenous thrombolysis is the most effective drug treatment for acute ischemic stroke at present.Hemorrhagic transformation after thrombolysis,especially symptomatic intracranial hemorrhage (sICH),will seriously affect the outcomes after intravenous thrombolysis,and even threaten the life of patients.Therefore,the prediction and treatment of sICH after intravenous thrombolysis is particularly important.This article reviews the prediction and treatment of sICH after intravenous thrombolysis.

Vascular recanalization is an important treatment method for acute ischemic stroke. Antiplatelet drugs combined with intravenous thrombolysis and endovascular therapy have become the research hotspots in recent years. Platelet glycoprotein Ⅱb/Ⅲa receptor antagonist is a new class of antiplatelet drugs that work by inhibiting the last common pathway in the platelet aggregation process. Its safety and effectiveness in the treatment of acute coronary syndrome have been proven, but its application in patients with acute ischemic stroke is still in the exploratory stage. This article reviews the application of tirofiban in the treatment of acute ischemic stroke reperfusion.