Objective To investigate the clinical features and treatment ofBrucellosis disease in children in recent years.Methods The clinical data of 24 children withBrucellosis disease admitted during January 2011 to December 2015 were retrospectively analyzed.Results In 24 children, 18 was male and 6 was female and average age was 9.8±3.13 years (4-14 years). Twenty-four children were diagnosed withBrucellosis disease by positive tiger red plate agglutination tests and their antibody titer was 1:800-1:100. The children lived mainly in the pastoral areas; four cases (16.67%) had sick family members and cattle and sheep; three cases (12.5%) had histoty of contact only with sick family members; 12 cases (50.00%) had cattle and sheep exposure history; 3 cases (12.5%) had raised cattle or sheep at home in the past 2 years; 2 cases (8.33%) had not have clear transmission route. The onset of the disease occurred year round, with the highest incidence in June and July. The common clinical symptoms were fever, arthralgia, weak, sweat, and anorexia, combined with hepatomegaly and splenomegaly. Patients younger than 8 years old were treated with rifampin and sulfamethoxazole. Patients equal to or older than 8 years old were treated with doxycycline and rifampin. Twenty-three children had been cured after treatment. Only one child stopped taking the drugs 3 weeks after discharge, which resulted in recurrence.Conclusion For children living in pasturing area suffered with unexplained recurrent fever, brucellosis disease should be considered and ruled out.

Objective To establish the WeChat platform of transitional care for the puerperal period,and to evaluate the application effect of the platform in improving neonatal care ability of primipara.Methods A total of 300 cases of primipara after spontaneous labor in the Third Affiliated Hospital of Zhengzhou University from September 2016 to September 2017 were selected as the research subjects.All the subjects were divided into observation group and control group by random number table method,with 150 cases in each group.During hospitalization,two groups of primipara received one-on-one health education.After discharge,the control group received the health guidance by telephone follow-up.The observation group received transitional care from WeChat platform.The neonatal growth status 42 days after delivery and the breast-feeding in 6 months were compared between the two groups.Results The duration of neonatal jaundice and umbilical cord separation in the observation group were shorter than those in the control group,and the differences were statistically significant (P＜0.05).There was no significant difference in umbilical cord infection between the two groups (P＞0.05).There were statistically significant differences between the two groups in neonatal care knowledge and breastfeeding rate at 6 months after delivery (P＜0.05).Conclusions Transitional care based on WeChat platform can improve newborn care ability of primipara and promote breastfeeding,which is worthy of clinical application.

ObjectiveTo explore the nursing students' experience of participation in group resuscitation workshop. MethodsFrom July to September of 2018,12 nursing interns in the Emergency Department of a Class Ⅲ Grade A hospital in Zhengzhou were recruited to participate in the study by purposive sampling and semi-structured interviews were conducted. The data obtained were analyzed by Colaizzi method. ResultsNursing students' experience of participation in the team recovery workshop can be summarized into three themes:teamwork awareness, independent learning ability and confidence,and stress and response. ConclusionsThe workshop promotes nursing students' sense of teamwork and stimulates their subjective initiative and ability to learn. It is suggested that nursing clinical education workers should attach importance to the various pressures faced by students and provide support from various angles.

BACKGROUND: Perioperative treatment has become an increasingly important aspect of the management of patients with non-small cell lung cancer (NSCLC). Small-scale clinical studies performed in recent years have shown improvements in the major pathological remission rate after neoadjuvant therapy, suggesting that it will soon become an important part of NSCLC treatment. Nevertheless, neoadjuvant immunotherapy may be accompanied by serious adverse reactions that lead to delay or cancelation of surgery, additional illness, and even death, and have therefore attracted much attention. The purpose of the clinical recommendations is to form a diagnosis and treatment plan suitable for the current domestic medical situation for the immune-related adverse event (irAE). METHODS: This recommendation is composed of experts in thoracic surgery, oncologists, thoracic medicine and irAE related departments (gastroenterology, respirology, cardiology, infectious medicine, hematology, endocrinology, rheumatology, neurology, dermatology, emergency section) to jointly complete the formulation. Experts make full reference to the irAE guidelines, large-scale clinical research data published by thoracic surgery, and the clinical experience of domestic doctors and publicly published cases, and repeated discussions in multiple disciplines to form this recommendation for perioperative irAE. RESULTS: This clinical recommendation covers the whole process of prevention, evaluation, examination, treatment and monitoring related to irAE, so as to guide the clinical work comprehensively and effectively. CONCLUSIONS Perioperative irAE management is an important part of immune perioperative treatment of lung cancer. With the continuous development of immune perioperative treatment, more research is needed in the future to optimize the diagnosis and treatment of perioperative irAE.