Objective To explore the significance of video-electroencephalography (VEEG)monitoring in the diagnosis of pediatric epilepsy.Methods One hundred and twenty patients undiagnosed pediatric epilepsy were under VEEG and conventional electroencephalography (EEG) monitoring,comparative analysis of these two results,and application of VEEG to determine the type of children with seizure.Results Conventional EEG monitoring detected the clinical onset of 21 cases (17.5％,21/120),epileptiform discharges of 30 cases (25.0％,30/120).VEEG monitoring detected the clinical onset of 55 cases (45.8％,55/120),epileptiform discharges of 89 cases (74.2％,89/120).There was significant difference in the monitoring results between two methods (P ＜0.05).VEEG monitoring of 120 patients undiagnosed pediatric epilepsy,final diagnosis of 87 cases with pediatric epilepsy,and the type were tonic and (or) clonic seizures 25 cases,simple partial seizures 13 cases,breath holding attacks 9 cases,absence petit mal 18 cases,complex partial seizures 10 cases,myoclonic seizures 12 cases.Conclusion VEEG has high sensitivity for the diagnosis of pediatric epilepsy,and can determine the type of seizures to provide help for the treatment.

Objective To explore the relapse type pediatric primary nephrotic syndrome happened related influencing factors,and to provide the reference of the clinical prevention and control.Methods Participants included 120 cases of primary nephrotic syndrome patients,according to its whether for relapse type divided into two groups,a detailed record of two groups of patients with basic information,the application of multiple factors regression analysis with factor analysis.Results 120 cases of primary nephrotic syndrome in children with 20 cases follow-up of 1 year relapse occurred,the recurrence rate was 16.7％.Single factor analysis results show that repeated infection,use of albumin was 2 times,use short treatment,the serum albumin level and IgG levels and relapse type pediatric primary nephrotic syndrome happened there was a close correlation,there was difference between the two groups (P ＜ 0.05).Multiple factors analysis results showed that repeated infection,use of albumin was 2 times and the low level of albumin is cause recrudesce type pediatric primary nephrotic syndrome happened independent risk factors (P ＜ 0.05).Conclusion Pediatric primary nephrotic syndrome recurrence occurred independent risk factors include repeated infection,use of albumin was 2 times and albumin level is low,in the clinical work for the above can intervention risk factors necessary intervention has important meaning,can reduce the risk of recurrence of children.

Objeaive To study the value ofvideo-electroencephalography(VEEG) for the diagnosis of children with non-epileptic seizures (NES).Methods A retrospective analysis was carried out in 280 patients with NES diagnosed by VEEG surveillance.All the patients underwent routine electroencephalography (EEG),VEEG,CT and MRI examination.Results Routine EEG was normal in 183 cases,and abnormal in 97 cases.VEEG recording was normal in 207 cases(73.9％,207/280),and abnormal in 73 cases(26.1％,73/280).The somatic NES was in 210 cases (75.0％,210/280),and psychogenic NES was in 70 cases (25.0％,70/280).NES combined with epilepsy were in 22 cases,MRI found 20 cases (90.9％,20/22) and head CT found 14 cases (63.6％,14/22).In the combined diagnosis,MRI was higher than CT in detecting focus (P ＜ 0.05).Conclusions VEEG is the important means of diagnosing children with NES,which is also important to differentiate with epilepsy.Combined with cranial imaging studies,it improves the identification of abnormal discharge and epilepsy,and further reveals the structural features of the epileptic discharge lesions is an important qualitative means of epilepsy etiological diagnosis.

Objective To observe the clinical effect of interferon aerpsp; in the treatment of pediatric viral upper respiratory tract infection disease.Methods 60 children with upper respiratory tract infection were divided randomly into two groups.The observation group were treated with interferon-α1b high atomization treatment of patients in the control group,with ribavirin injection treatment,two groups of patients were treated for 7 days.After a comparison of clinical outcomes.Results The total efficiency of the observation group was 90％,which was significantly higher than that of the control group(70％) (x2 =5.684,P ＜0.05) ; The fever retrcating time in observation group was (16.39 ± 5.34) h,whichwas significantly shorter than that in control group[(16.39 ± 5.34) h] (t =3.584,P ＜ 0.05).Conclusion For children virus upper respiratory tract infection treated by interferon treatment,atomization,having remarkable curative effect,and can effectively reduce the adverse reaction,enhance safety,clinical is a recommendable method.

Objective To analyze the value of video electroencephalogram (VEEG) and brain imaging in diagnosis of epilepsy.Methods The routine electroencephalogram (REEG),VEEG,brain MRI and CT results of 112 patients with epilepsy were compared.Results In 112 epilepsy patients,39 patients (34.8％) showed epileptic focus in REEG,and 87 patients (77.7％) showed epileptic focus in VEEG.Seventy patients (62.5％) revealed lesions by brain MRI examination,37 patients (33.0％) revealed lesions by brain CT examination.Focal abnormal rate of brain MRI examination had significant difference between focal discharge patients and diffuse discharge patients [58.9％ (43/73) vs.21.4％ (3/14)] (P ＜0.01).Positioning accuracy had significant difference between temporal lobe discharge and outside temporal lobe discharge [53.1％(17/32) vs.26.8％(11/41)](P＜ 0.01).Conclusions Rate of epileptic discharge found by VEEG is significantly higher than that by REEG.Brain MRI displays epileptic discharge lesions better than brain CT,and MPd is an important method to find epileptic focus localization.It has a certain relationship between these two methods.It has a very important significance to combine with both methods in diagnosis of epilepsy.

OBJECTIVE To explore the drug resistance rate and risk factor of Pseudomonas aeruginosa against ceftazidime in a certain hospital,and provide scientific basis for preventing the P.aeruginosa infections.METHODS A total of 109 P.aeruginosa strains,which were isolated from sputum cultures in patients in a certain hospital in 2005,were identified with VITEK GNI+ automation system.The possible risk factors and underlying diseases were investigated by reviewing patients′ medical records.Multiple Logistic regression models were used for statistical analyses by SPSS software(13.0).RESULTS The resistant ratios against ceftazidime was 38.5%.P.aeruginosa resistant ratios in ICU and the neurosurgery ward were 78.57% and 54.84%,respectively,and higher than others.Treatment days before infection in hospital(over two days),staying at the ICU or neurosurgery ward,using breathing machine,were associated with the sensitivity to ceftazidime for P.aeruginosa.CONCLUSIONS In order to prevent and reduce the drug resistant ratios for P.aeruginosa,we should pay more attention to the patients admitted in ICU and neurosurgery wards.Risk factors,such as treatment days in hospital,living in different wards and using breathing machine,were associated with the resistant ratios for P.aeruginosa against ceftazidime.

Objective To analyze the cause of poor stumps and to introduce the methods of treatment, so that the rate of poor stump would be decreased. Methods We evaluate 109 cases of lower limb amputees with a total of 110 residual limbs. Evaluation content included: Skin (scars, dermatitis, folliculitis, open wounds, tactile and pain sensation); characteristics of residual limb shape (conical, bulbous, edematous cylindrical); strength of the stump; range of motion of the residual limb; muscle tone; strength of the stump and phantom pain. Results Forty-six cases out of 110 are unqualified. All poor stumps can be fit with the prosthetic through rehabilitation care. Conclusion Poor stumps are those unsuitable for fitting of the prosthetic. Special treatments are required to fit them with prosthetic. Because of the improvement of the prosthetic technology, length of the residual limb is no longer the main obstruction for fitting prosthetic. Instead the skin soft tissue condition of the stump is becoming the main reason of failure in fitting the prosthetic.

Objective To study the best method for myoelectric feedback training and evaluate the effectiveness of myoelectric artificial hand. Methods Fourteen cases of upper limb amputees (11 male, 3 female, aged 25?8.69 years, right side 13, left side 3,totally 16 myoelectric artificial hands) were recruited for this study. The biofeedback training process was divided into three steps: basic signal of myoelectric feedback training, visible feedback training, and ADL function training. Results After the training, 16 myoelectric artificial hands could grasp, pinch and rotate wrist, and could perform ADL such as dressing, eating, cleaning. Conclusion To achieve the goal set for the myoelectric artificial hand, emphasis should be on locating the most stronger myoelectric signal of the stump and strengthening the feedback training.

OBJECTIVE:To establish a HPLC method for determining the content of fluvastatin sodium in fluvastatin sodium extended-release tablets. METHODS:An Agilent SB-C18 column was used and the mobile phase was CH3CN-0.1% phosphate acid, 50∶50. Flow rate was 1mL?min-1, wavelength was 234nm and the sample size was 20?L. RESULTS:The fluvastatin sodium concentration had good liner relationship from 4.84～96.8?g?mL-1(r=0.999 9), and the average recovery was 100.1%,RSD=0.9%. CONCLUSION:This method was simple, fast, accurate, and precise, could be used to determine content in fluvastatin sodium extended-release tablets.

Objective To analyze the effect of different methods of anesthesia maintenance on clinical efficacy and postoperative recovery in elderly patients with gynecological diseases undergoing laparoscopic surgery.Methods A total of 80 elderly patients with gynecological diseases scheduled for laparoscopic surgery were enrolled in this study in our hospital from January 2015 to December 2016.All the patients were randomly divided into two groups of anesthesia maintenance:an intravenous anesthesia alone (n=40) and a combined intravenous and inhaled anesthesia (n =40).The pre-and post-anesthesia changes in arterial blood gas,blood pressure,heart rate and cognitive function,and postoperative complications were analyzed and compared between the two groups.Results There were no significant differences between the two groups in the times of palinesthesia,extubation and talking (all P＞ 0.05).After anesthesia,the levels of arterial blood gas,the blood pressure and the heart rate were relatively stable in both groups,and their differences between the two groups were without statistically significant (all P ＞ 0.05).While,the postoperative cognitive function recovered more rapidly in patients receiving intravenous anesthesia alone for anesthesia maintenance than in those receiving a combined intravenous and inhaled anesthesia,especially at 6 h after extubation.The Mini-mental State Examination (MMSE) score was significantly higher in patients receiving intravenous anesthesia alone (28.8 ± 0.5) than in patients receiving a combined intravenous and inhaled anesthesia (25.1 ±0.6),with statistically significant difference (P＜ 0.05).In addition,there was no statistical difference between the two groups in the incidence of complications.Conclusions As anesthesia maintenance,both an intravenous anesthesia alone and a combined intravenous and inhaled anesthesia can ensure a successfully laparoscopic surgery for gynecological diseases in elderly patients.However,the impact on cognitive function after laparoscopic surgery is smaller in the maintenance of intravenous anesthesia alone than in a combined intravenous and inhaled anesthesia in elderly patients.Intravenous anesthesia alone can be used in elderly patients to receive laparoscopic surgery as routine anesthesia maintenance.