1.Grade of membership analysis of multidimensional health status in adult twins
Yan NING ; Wenyan JI ; Yonghua HU ; Yueqin HUANG ; Weihua CAO ; Jun LV ; Ying QIN ; Zengchang PANG ; Shaojie WANG ; Liming LI
Chinese Journal of Disease Control & Prevention 2009;0(02):-
Objective To construct profiles of health status based upon physical,mental and social support items in adult twins of Qingdao.Methods Grade of Membership(GoM) model was applied to a set of 31 indicators to construct ideal profiles.Results Four health profiles were identified: pure type Ⅰ(healthy),pure type Ⅱ(personality disorders),pure type Ⅲ(psychological symptoms) and pure type Ⅳ(physiological symptoms).The most frequently occurring combination in this population was profile Ⅰ,Ⅱ,Ⅳ(14.74%),followed by profile Ⅰ,Ⅱ,Ⅲ,Ⅳ(13.44%),and then type Ⅰ(11.08%).Only 13.56% of subjects fell completely into one single pure type.Conclusions One healthy type and three non-healthy types are determined.Most individuals exhibit some of the characteristics of two or more types,holding partial membership in multiple categories.
3. Association of lipid parameters with insulin resistance in different glycemic among the elderly population
Shaojie PANG ; Qingqing MAN ; Shuang SONG ; Pengkun SONG ; Zhen LIU ; Yuqian LI ; Li HE ; Wenhua ZHAO ; Jian ZHANG
Chinese Journal of Preventive Medicine 2018;52(6):629-635
Objective:
This study was to analyze the association of lipid parameters with insulin resistance of Chinese elderly population in different glycemic status.
Methods:
Data were from China National Chronic Diseases and Nutrition Survey (2015). A total of 15 535 participants aged 60 and above who had completed survey questionnaire, physical examination, fasting blood biochemistry and insulin measurements were included in this study. According to the American Diabetes Association (2010) criteria, the participants were divided into normal glucose regulation, pre-diabetes, newly-diagnosed diabetes and previously-diagnosed diabetes. Multivariable logistic regression was preformed to assess the effects of lipid parameters on insulin resistance in different glycemic among the elderly population.
Results:
The proportion of normal glucose regulation, pre-diabetes, newly-diagnosed diabetes and previously-diagnosed diabetes was 50.46% (
4.A twin study in Qingdao and Lishui:heritability of exercise participation and sedentary behavior
Feng ZHANG ; Wenjing GAO ; Canqing YU ; Jun LYU ; Shengfeng WANG ; Siyan ZHAN ; Yonghua HU ; Zengchang PANG ; Weijian CHEN ; Shaojie WANG ; Rongfu CHEN ; Weihua CAO ; Liming LI
Chinese Journal of Epidemiology 2014;(6):630-634
Objective To investigate both genetic and environmental influences on the exercise participation and sedentary behavior in Qingdao,Shandong province and 326 in Lishui, Zhejiang province. Methods 568 twin pairs,including 242 in Qingdao and 326 in Lishui,were studied. Exercise participation was measured by two questions on the frequency and intensity and then divided into two groups. Sedentary behavior was measured by one question as‘how long do you spend on sitting every day’. Variance component models based on twins was used to estimate the genetic and environmental factors on these traits. Results The average age in monozygotic twins was(41.14 ± 10.11)while in dizygotic twins it was(41.23 ± 9.89). Genetic factors accounted 78%(35%-96%)and 59%(0-94%)for exercise participation variance in Qingdao and Lishui in people aged between 20 and 40. However,there were no heritability noticed on physical activity in people older than 40 years of age. Rates of heritability on sedentary behavior in Qingdao and Lishui were 68%(59%-75%)and 32%(7%-62%),respectively. Conclusion Results from the study suggested that sedentary behavior in Chinese people was influenced by genetic factors,which could also explain much of the exercise participation variance in people aged between 20 and 40.
5.Weight change in association with the incidence of type 2 diabetes in adults from Qingdao, China.
Feng NING ; Shaojie WANG ; Yumei WANG ; Jianping SUN ; Lei ZHANG ; Weiguo GAO ; Hairong NAN ; Jie REN ; Qing QIAO ; Zengchang PANG ; null ; null
Chinese Journal of Epidemiology 2014;35(7):764-768
OBJECTIVESince the incidence rates and risk factor for type 2 diabetes in Chinese populations had not been well known, the aim of this study was to evaluate the impact of weight change and other risk factors on incident type 2 diabetes in Qingdao, China.
METHODSA prospective population-based cohort study was carried out, based on subjects aged 35-74 years who participated in the 'Qingdao Diabetes Survey' in 2006. Subjects were free of diabetes at baseline. A total of 1 294 subjects attended the follow up survey between 2009 and 2011. The diagnostic criteria for Diabetes was classified according to both the World Health Organization and the International Diabetes Federation 2006. A logistic regression was built using the backward stepwise selection to assess the effects of risk factors on the incident type 2 diabetes.
RESULTSDuring a 4-year follow up period, 120 cases with incident type 2 diabetes were identified, with cumulative incidence of diabetes as 11.8% . Participants who developed type 2 diabetes were significantly older, having significantly higher age-adjusted BMI/waist circumference/systolic blood pressure and total cholesterol, than those subjects who remained non-diabetic both in urban and rural areas. Among individuals with no diabetes at the baseline, factors as age, living in the rural areas, baseline BMI and weight change had all independently contributed to the development of diabetes. The multivariate adjusted relative risks (95%CIs) related to the incidence of diabetes were 1.45 (1.13-1.87), 1.93 (1.12-3.34), 1.46 (1.05-2.03) and 1.49 (1.18-1.88), respectively, for a one standard deviation increase in continuous variables. Compared with the reference group of non-obese and with stable weight, factor as weight loss >5% and BMI <28 kg/m² were independently associated with a 67% (RR = 0.33, 95% CI: 0.11-0.97)reduction in the risk of type 2 diabetes, while BMI >28 kg/m² could increase the risk across the levels of weight change. Similar trends were observed in higher waist and weight gain at baseline.
CONCLUSIONThis study confirmed the critical importance of obesity in the development of type 2 diabetes. Baseline BMI and weight gain appeared independent predictors on type 2 diabetes.
Adult ; Aged ; Body Mass Index ; Body Weight ; China ; epidemiology ; Diabetes Mellitus, Type 2 ; epidemiology ; Female ; Follow-Up Studies ; Humans ; Incidence ; Logistic Models ; Male ; Middle Aged ; Prospective Studies ; Risk Factors ; Weight Gain
6.Relationship between finger dermatoglyphics and body size indicators in adulthood among Chinese twin population from Qingdao and Lishui cities.
Luanluan SUN ; Canqing YU ; Jun LYU ; Weihua CAO ; Zengchang PANG ; Weijian CHEN ; Shaojie WANG ; Rongfu CHEN ; Wenjing GAO ; Liming LI
Chinese Journal of Epidemiology 2014;35(1):22-26
OBJECTIVETo study the correlation between fingerprints and body size indicators in adulthood.
METHODSSamples were composed of twins from two sub-registries of Chinese National Twin Registry (CNTR), including 405 twin pairs in Lishui and 427 twin pairs in Qingdao. All participants were asked to complete the field survey, consisting of questionnaire, physical examination and blood collection. From the 832 twin pairs, those with complete and clear demographic prints were selected as the target population. Information of Fingerprints pixel on the demographic characteristics of these 100 twin pairs and their related adulthood body type indicators were finally chosen to form this research. Descriptive statistics and mixed linear model were used for data analyses.
RESULTSIn the mixed linear models adjusted for age and sex, data showed that the body fat percentage of those who had arches was higher than those who did not have the arches (P = 0.002), and those who had radial loops would have higher body fat percentage when compared with ones who did not (P = 0.041). After adjusted for age, there appeared no statistically significant correlation between radial loops and systolic pressure, but the correlations of arches (P = 0.031)and radial loops (P = 0.022) to diastolic pressure still remained statistically significant.
CONCLUSIONStatistically significant correlations were found between fingerprint types and body size indicators, and the fingerprint types showed a useful tool to explore the effects of uterine environment on health status in one's adulthood.
Adult ; Body Size ; Dermatoglyphics ; Diseases in Twins ; epidemiology ; Female ; Health Status ; Humans ; Male ; Surveys and Questionnaires ; Twins
7.A twin study in Qingdao and Lishui: heritability of exercise participation and sedentary behavior.
Feng ZHANG ; Wenjing GAO ; Canqing YU ; Jun LYU ; Shengfeng WANG ; Siyan ZHAN ; Yonghua HU ; Zengchang PANG ; Weijian CHEN ; Shaojie WANG ; Rongfu CHEN ; Weihua CAO ; Liming LI
Chinese Journal of Epidemiology 2014;35(6):630-634
OBJECTIVETo investigate both genetic and environmental influences on the exercise participation and sedentary behavior in Qingdao, Shandong province and 326 in Lishui, Zhejiang province.
METHODS568 twin pairs, including 242 in Qingdao and 326 in Lishui, were studied. Exercise participation was measured by two questions on the frequency and intensity and then divided into two groups. Sedentary behavior was measured by one question as 'how long do you spend on sitting every day'. Variance component models based on twins was used to estimate the genetic and environmental factors on these traits.
RESULTSThe average age in monozygotic twins was (41.14 ± 10.11)while in dizygotic twins it was (41.23 ± 9.89). Genetic factors accounted 78% (35%-96%) and 59% (0-94%) for exercise participation variance in Qingdao and Lishui in people aged between 20 and 40. However, there were no heritability noticed on physical activity in people older than 40 years of age. Rates of heritability on sedentary behavior in Qingdao and Lishui were 68% (59%-75%) and 32% (7%-62%), respectively.
CONCLUSIONResults from the study suggested that sedentary behavior in Chinese people was influenced by genetic factors, which could also explain much of the exercise participation variance in people aged between 20 and 40.
Adult ; China ; Cross-Sectional Studies ; Exercise ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Sedentary Lifestyle ; Surveys and Questionnaires ; Twins ; genetics ; Young Adult
8. A cohort study on the association between dietary patterns which benefit for normal kidney function and the cognitive performance in the Chinese elderly
Zhaoxue YIN ; Zeping REN ; Gang JING ; Dan LIU ; Jian ZHANG ; Zhuoqun WANG ; Mei ZHANG ; Yi ZHAI ; Pengkun SONG ; Yanfang ZHAO ; Shaojie PANG ; Shengquan MI ; Wenhua ZHAO
Chinese Journal of Epidemiology 2019;40(4):427-432
Objective:
To explore the association between dietary pattern which benefit for normal kidney function and the risk of cognitive decline or impairment in the elderly.
Methods:
In 2015, subjects aged 60 and over from four counties in the Nutrition and Chronic Disease Family Cohort project, were followed up in 2017. Cognitive function was repeatedly assessed, using the Mini Mental State Evaluation (MMSE) scale. Dietary pattern that benefit for normal kidney function was extracted, using the reduced rank regression method and followed by logistic regression models to explore the associations between scores that showing the kidney function on dietary patterns and the risk of cognitive deterioration and impairment in two years among those who were with normal cognition in 2015.
Results:
Dietary pattern that benefit for normal kidney function, was characterized by high consumption of cereal, vegetables, legume and fruits but with less meat and soy products. Comparing with the group with lowest score quartile on this dietary pattern, the risk of cognitive deterioration in the highest quartile group was significantly low (
9. Association between fruit consumption and stroke in adults in Qingdao: a prospective study
Xiaocao TIAN ; Shaojie WANG ; Shanpeng LI ; Yu GUO ; Zheng BIAN ; Silu LYU ; Wenying QU ; Jiben LIU ; Ruqin GAO ; Zengchang PANG ; Liming LI ; Zhengming CHEN
Chinese Journal of Epidemiology 2019;40(5):515-520
Objective:
To understand the fruit consumption of adults of Qingdao and examine the association between fruit consumption and stroke.
Methods:
We analyzed baseline data and stroke incidence of the participants who were aged 30-79 years and had been enrolled into the China Kadoorie Biobank (CKB) study from Qingdao city. Cox proportional hazards regression model was conducted to estimate the association of fruit consumption with risk of stroke.
Results:
A total of 35 509 participants were investgated in the baseline survey. Ratio of male to female was 1∶1.27, and the average age was (50.3±10.2) years. Respondents with higher frequency of fruit consumption were younger, more women, with higher education level and higher income (
10. Blood pressure changes in 18-59 years old adults in rural area of Shanxi province, China
Yanfang ZHAO ; Chenglian LI ; Xiangyang WEI ; Yanbin WEN ; Zhuoqun WANG ; Mei ZHANG ; Yi ZHAI ; Jian ZHANG ; Pengkun SONG ; Shaojie PANG ; Zhaoxue YIN ; Shengquan MI ; Wenhua ZHAO
Chinese Journal of Epidemiology 2019;40(5):548-553
Objective:
To analyze the blood pressure changes of adults aged 18-59 years in rural area of Shanxi province based on a cohort study, and provide reference for the study of the blood pressure level of rural residents and hypertension prevention and control in rural areas in China.
Methods:
Data were obtained from Shanxi Nutrition and Chronic Disease Family Cohort from 2002 to 2015. Subjects aged <18 years or ≥60 years and individuals with hypertension at baseline survey in 2002, and those who had taken antihypertensive drugs for nearly two weeks during the follow-up survey in 2015 were excluded from the study. A total of 1 629 subjects aged 18-59 years were included in the analyses of the blood pressure level and its change from the baseline survey in 2002 to follow-up survey in 2015.
Results:
The systolic blood pressure (SBP) of the subjects increased from (122.7±10.4) mmHg in 2002 to (132.8±17.6) mmHg in 2015 and the diastolic pressure (DBP) increased from (72.7±6.9) mmHg in 2002 to (78.8±10.3) mmHg in 2015. The SBP in men and women increased with growth rates of 6.7% and 9.5%. While DBP in men and women increased with growth rates of 9.3% and 7.8%. The SBP levels of those aged 18-, 30-, 40- and 50-59 years increased with growth rates of 5.0%, 6.7%, 9.4% and 11.8%. While the DBP of these age groups increased with growth rates of 12.2%, 8.2%, 8.2% and 6.5%.
Conclusions
The blood pressure of adults aged 18-59 years old in rural area of Shanxi showed a substantially increasing trend. The mean increase level of SBP in women was higher than that in men, and increased with age. While the mean increase level of DBP in men is higher than that in women, and decreased with age.