Objective To investigate the surgical procedure of covering two soft tissue defects on a lower leg simultaneously.Methods 3 cases with two soft tissue defects on a lower leg were treated with two combined fascia pedisled island flaps.The reversed fascia pediclod island flap supplied by perforating branches of anterior tibial artery was combined with that by perforating branches of posterior libial artery,the reversed fascia pedicled island (lap of superior medial malleolus was combined with that uf the post lower leg,and the reversed fascia pedicled island flap of superior medial malleolus was combined with the reversed fascia pedicled island flap supplied by perforating branches of anterior tibial artery.Results All flaps survived and the surfaces of the wounds healed well.Conclusion It is a safe,simple and practical method to cover two soft tissue defects on the lower leg with two fascia pedicled island flaps supplied by perforating branches of main arteries of the leg.

Aim To observe the action of hydroxyanthroquinones from Rheum Palmatum L on reduced jaundice and enzyme in acute jaundice model of rat induced by ANIT.Methods Wistar rats were randomized into five groups: group A in which no treatment was given,group B in which ANIT was given on the eighth day,group C in which high dosage of hydroxyanthroquinones from Rheum Palmatum L was given,group D in which low dosage of hydroxyanthroquinones from Rheum Palmatum L was given,group E in which "Yinzhihuang injection" was given as positive control.Except group A and B,other groups were given corresponding drugs for 7 days and then additionally administered ANIT to induce jaundice on the eighth day.Forty-eight hours later,the rats′ blood was gained from eyes and the serum was separated.The liver functional sign,the activity of SOD,the content of MDA in serum and change in pathology of liver tissue were observed.Results Compared to group B,ALT,AST,TBIL,ALP,?-GT ,MDA of group C and E descended obviously(P0.05).Conclusion Hydroxyanthroquinones from Rheum Palmatum L has the action of reducing serum bilirubin and transaminase and improving liver tissue injury in rats of experimental Cholestasis.

Objective To evaluate the clinical effect of homemade Drug-eluting stent.Methods47 patients were treated with drug-eluting stents(63 stents).All patients who received angiography were followed up for 2~12 months after stents implant.The mortality,target vessel revascularization ratio and major adverse cardiac events were recorded.ResultsFor follow-up 47 patients,the mortality,target vessel revascularization ratio and major adverse cardiac events were 2.1%,2.1%,6.4%.ConclusionHomemade Drug-eluting stent is safe and effective.

Objective To study the diagnostic value in examination of cat scratch disease with CT.Methods The features of contrast enhanced CT scans in 3 cases with cat scratch disease proved by pathology and operation were analysed.Results Three cases all had clear scratches and contact history,lymph node enlargement along the regional lymphatic drainage was seen and presented as circular enhancementon CT.Conclusion To untypical patients with cat-scratch disease the contrast enhanced CT scans can show the local lymphatic pathological change and may help to comfirm the diagnosis.

Objective To share the treatment experience of 56 cases with acute Stanford A aortic dissection in the Xingtai People's Hospital of the past 5 years.Methods Clinical data of 56 cases with Stanford A aortic dissection were retrospective analyzed.Results Before operation,5 patients died,and 3 patients abandoned treatment.Two patients took expectant treatment for one month and finally left hospital.After operation,1 patients abandoned treatment,and 4 patients died.Other 41 patients were cured.After operation,7patients had low cardiac output syndrome,10 patients had severe pulmonary infection,12 patients had brain damage temporarily,2 patients had permanent brain damage,8 patients had renal inadequacy (3 patients had renal failure before operation),and 5 patients were required hemodialysis.Conclusion Surgical treatment is proved to be an effective method to cure patients with Stanford A aortic dissection.

Objective To discuss the microsurgical treatment for tethered cord syndrome (TCS) caused by intraspinal lipomas. Methods Thirty-two patients with intraspinal lipoma TCS were treated microsurgically. On surgery the tethering lesions of lipoma were excised and anomalies restricting the spinal cord were removed. Results Following the operation, cerebrospinal fluid subcutaneous leakage had occurred in 3 patients, who were cured by expectant treatment. The patients were followed for 3~12 months (mean, 6 months). Five patients were cured, 21 got improved, and 6 had no change. Conclusions Application of microsurgical technique for intraspinal lipoma TCS has advantages of fewer complications and better improvement of nerve functions.

Objective To investigate advantages and disadvantages of unilateral hemilaminectomy for the microsurgical removal of cervical intraspinal tumors. Methods Twenty-three patients with cervical intraspinal tumors were treated microsurgically with unilateral hemilaminectomy. In condition that the vertabral lamina was kept intact in bony structure, an opening (key-hole) was made in the unilateral lamina by using a drill or a small-sized bone rongeur. Then cervical intraspinal tumors were removed via the “key-hole”. Results Tumors were completely removed in all the 23 patients and no symptoms relating nerve injuries were observed. Postoperative follow-up for 3~16 months (mean, 8 months) revealed no recurrence and spinal deformity. Conclusions Unilateral hemilaminectomy for the treatment of cervical intraspinal tumors is a mini-invasive procedure which benefits the spinal stability. The pitfall of the technique lies in limited surgical field.

Objective To observe the effects and mechanism of ischemic postconditioning(IPo) on alleviating injuries of small intestine and remote organs induced by intestinal ischemia-reperfusion (IR).Methods A total of 48 rabbits were divided randomly into three groups(n =16 in each):the Sham group,the IR group and the IPo group.After 2 hours of reperfusion,arterial and venous blood and tissues of intestine,liver and lung were harvested.The levels of TNF-α,IL-1β,IL-6 and IL-10 in arterial blood and levels of ALT,AST,BUN,Cr,LDH,CK-MB activity and endotoxin in venous blood were tested.MDA, CAT,SOD and MPO levels in serum,small intestine,liver and lung were also measured.HE staining was performed for observation of injured intestinal mucosa.Bacterial translocation rate was calculated after bac-teria culture.Results Compared with the IR group,MDA and MPO levels in serum,small intestine,liver and lung decreased in the IPo group,while CAT and SOD levels increased obviously.Compared with the IR group,ALT,AST,LDH,CK-MB and BUN levels in the venous blood,and TNF-α,IL-1β,IL-6 and endotox-in levels in arterial blood were all decreased.IL-10 increased and the intestinal mucosal injury score de-creased obviously.Conclusion Ischemic post conditioning can decrease the damage of intestinal mucosa, reduce endotoxin translocation,promote activation of anti-inflammatory cytokines,inhibit excessive release of inflammatory mediators,enhance the antioxidant capacity of intestine and remote organs,reduce injuries to the small intestine and remote organs.

Objective: To summarize the clinical experiences and effect of laparoscopic cholecystectomy(LC)combined with laparoscopic appendectomy(LA). Methods: The clinical data of 92 cases which successfully underwent three-trocar LC and LA was retrospectively analyzed. Results: All operations were performed successfully without complications. The mean operation time was 70 min. The mean hospital stay was 5 days. No complications occurred in the 85 cases who were followed up in 6 months. Conclusion: The simultaneous approach to LC and LA is a safe and effective treatment.