ObjectiveTo observe the status and related factors of depression symptoms in elders.MethodsRandomized multi-stage sampling method was used to select subjects.504 elders ( aged ≥65 years) in Jining were investigated and assessed by using the scales of Geriatric Depression Scale15 ( GDS-15 ),Katz-activity of daily liying (Katz-ADL) and Lawton instrumental ADL (IADL).ResultsThe GDS scores of males (2.24 ±2.12 ) were significantly lower than that of females ( 3.35 ± 3.49) ( t '=4.236,P ＜ 0.01 ).There were significant differences in GDS scores among different subgroups of age,single or not,physical activity,sleep quality,self-reported health,living condition,economic status and lonely feeling.GDS scores were significantly correlated to lonely feeling,IADL,living condition,economic status,self-reported health and age (F =27.47,P ＜ 0.001 ; R2 =0.372,R'2 =0.358 ),with the total contribution of 35.8％.ConclusionAmong elders,the main factors influencing depression symptoms are lonely feeling,IADL,female,health condition,economic condition and single,respectively.Enhancing IADL of elders can contribute to reduce the risk factors of depression.

ObjectiveTo investigate the application effect of doctor-nurse-patient-family four-in-one integrated home care in treatment and rehabilitation of patients with reflux esophagitis.Methods A total of 138 patients with reflux esophagitis,treated in Department of Spleen and Stomach Disease in the Hospital of Shanxi University of TCM from March to October 2016,were selected and divided into control group and observation group according to randomized grouping method and program SAS 8.2 proc uniform. Totals of 69 patients in the control group received conventional nursing care,while other 69 in the observation group were intervened by the doctor-nurse-patient-family four-in-one integrated home care (RE-HC). After completion of the 12-week intervention,total score of symptoms,total effective rate of the clinical treatment,comprehensive score of nursing management effect and quality of life score were compared between the two groups.Results Total score of symptoms in the observation group (16.54±4.82) was obviously lower than that in the control group (28.65±6.55) (Z=12.37,P<0.01). In the observation group,total effective rate of the clinical treatment was 97.10%,the score of nursing management effect was (125.98±3.46),and the total score of quality of life was (86.31±5.80),all higher than those in the control group (χ2/Z=5.90,68.03,1.41;P<0.05).Conclusions In treatment of patients with reflux esophagitis,the doctor-nurse-patient-family four-in-one integrated home care can remarkably improve the patients' symptom score,total effective rate,nursing management effect and the patients' quality of life.

OBJECTIVETo identify the endophytic fungal strain PR35 separated from Paeonia delavayi and study chemical constituents of its secondary metabolites.

METHODThe fungal strain PR35 was identified by morphological observation and ITS rDNA sequence analysis. Various chromatographic methods were adopted to separate and purify its secondary metabolites, and their structures were identified by physiochemical properties and spectral data

RESULTThe fungal strain PR35 was identified as Trichoderma longibrachiatum. Five compounds were separated from fermentation products of fungal strain PR35 and identified as 1-(2,6-dihydroxyphenyl)-3-hydroxybutan-1-one (1), 1-(2,6-dihydroxypheny) propan-1-one (2), 1-(2,4,6-trihydroxyphenyl) butan-1-one (3), 4-methoxy-1-naphthol (4), and cerevisterol (5). Among them, compounds 1-3 showed notable antifungal activities against Botrytis cinerea, Fusarium avenaceum and Hormodendrum compactum.

CONCLUSIONThe endophytic fungus T. longibrachiatum was separated from the plant P. delavayi for the first time. Five compounds were first separated from endophytic fungus of P. delavayi. Among them, compound 4 was separated from microbial fermentation products for the first time.

DNA, Fungal ; genetics ; DNA, Intergenic ; genetics ; Endophytes ; classification ; genetics ; isolation & purification ; metabolism ; Paeonia ; microbiology ; Phylogeny ; Trichoderma ; classification ; genetics ; isolation & purification ; metabolism